MiMIR: R-shiny application to infer risk factors and endpoints from Nightingale Health’s (1)H-NMR metabolomics data

por Bizzarri, D, Reinders, M J T, Beekman, M, Slagboom, P E, van den Akker, E B
Publicado 2022

1H-NMR metabolomics-based surrogates to impute common clinical risk factors and endpoints

por Bizzarri, D., Reinders, M.J.T., Beekman, M., Slagboom, P.E., BBMRI-NL, van den Akker, E.B.
Publicado 2021

How to deal with the early GWAS data when imputing and combining different arrays is necessary

por Uh, Hae-Won, Deelen, Joris, Beekman, Marian, Helmer, Quinta, Rivadeneira, Fernando, Hottenga, Jouke-Jan, Boomsma, Dorret I, Hofman, Albert, Uitterlinden, André G, Slagboom, P E, Böhringer, Stefan, Houwing-Duistermaat, Jeanine J
Publicado 2012

Non-response to (statin) therapy: the importance of distinguishing non-responders from non-adherers in pharmacogenetic studies

por Trompet, S., Postmus, I., Slagboom, P. E., Heijmans, B. T., Smit, R. A. J., Maier, A. B., Buckley, B. M., Sattar, N., Stott, D. J., Ford, I., Westendorp, R. G. J., de Craen, A. J. M., Jukema, J. W.
Publicado 2015

Genomics of human longevity

por Slagboom, P. E., Beekman, M., Passtoors, W. M., Deelen, J., Vaarhorst, A. A. M., Boer, J. M., van den Akker, E. B., van Heemst, D., de Craen, A. J. M., Maier, A. B., Rozing, M., Mooijaart, S. P., Heijmans, B. T., Westendorp, R. G. J.
Publicado 2011

Anxiety and depression in children and adults: influence of serotonergic and neurotrophic genes?

por Middeldorp, C M, Slof-Op 't Landt, M C T, Medland, S E, van Beijsterveldt, C E M, Bartels, M, Willemsen, G, Hottenga, J-J, de Geus, E J C, Suchiman, H E D, Dolan, C V, Neale, M C, Slagboom, P E, Boomsma, D I
Publicado 2010

Human longevity is characterised by high thyroid stimulating hormone secretion without altered energy metabolism

por Jansen, S. W., Akintola, A. A., Roelfsema, F., van der Spoel, E., Cobbaert, C. M., Ballieux, B. E., Egri, P., Kvarta-Papp, Z., Gereben, B., Fekete, C., Slagboom, P. E., van der Grond, J., Demeneix, B. A., Pijl, H., Westendorp, R. G. J., van Heemst, D.
Publicado 2015

Serum fatty acid chain length associates with prevalent symptomatic end-stage osteoarthritis, independent of BMI

por Meessen, J. M. T. A., Saberi-Hosnijeh, F., Bomer, N., den Hollander, W., van der Bom, J. G., van Hilten, J. A., van Spil, W. E., So-Osman, C., Uitterlinden, A. G., Kloppenburg, M., Nelissen, R. G. H. H., van Duijn, C. M., Slagboom, P. E., van Meurs, J. B. J., Meulenbelt, I.
Publicado 2020

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts

por van Leeuwen, N., Nijpels, G., Becker, M. L., Deshmukh, H., Zhou, K., Stricker, B. H. C., Uitterlinden, A. G., Hofman, A., van ’t Riet, E., Palmer, C. N. A., Guigas, B., Slagboom, P. E., Durrington, P., Calle, R. A., Neil, A., Hitman, G., Livingstone, S. J., Colhoun, H., Holman, R. R., McCarthy, M. I., Dekker, J. M., ’t Hart, L. M., Pearson, E. R.
Publicado 2012

Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains

por Kananen, L., Enroth, L., Raitanen, J., Jylhävä, J., Bürkle, A., Moreno-Villanueva, M., Bernhardt, J., Toussaint, O., Grubeck-Loebenstein, B., Malavolta, M., Basso, A., Piacenza, F., Collino, S., Gonos, E. S., Sikora, E., Gradinaru, D., Jansen, E. H. J. M., Dollé, M. E. T., Salmon, M., Stuetz, W., Weber, D., Grune, T., Breusing, N., Simm, A., Capri, M., Franceschi, C., Slagboom, P. E., Talbot, D. C. S., Libert, C., Koskinen, S., Bruunsgaard, H., Hansen, ÅM., Lund, R., Hurme, M., Jylhä, M.
Publicado 2021

Genetic association analysis of LARS2 with type 2 diabetes

por Reiling, E., Jafar-Mohammadi, B., van ’t Riet, E., Weedon, M. N., van Vliet-Ostaptchouk, J. V., Hansen, T., Saxena, R., van Haeften, T. W., Arp, P. A., Das, S., Nijpels, G., Groenewoud, M. J., van Hove, E. C., Uitterlinden, A. G., Smit, J. W. A., Morris, A. D., Doney, A. S. F., Palmer, C. N. A., Guiducci, C., Hattersley, A. T., Frayling, T. M., Pedersen, O., Slagboom, P. E., Altshuler, D. M., Groop, L., Romijn, J. A., Maassen, J. A., Hofker, M. H., Dekker, J. M., McCarthy, M. I., ’t Hart, L. M.
Publicado 2009

Short telomere length is associated with impaired cognitive performance in European ancestry cohorts

por Hägg, S, Zhan, Y, Karlsson, R, Gerritsen, L, Ploner, A, van der Lee, S J, Broer, L, Deelen, J, Marioni, R E, Wong, A, Lundquist, A, Zhu, G, Hansell, N K, Sillanpää, E, Fedko, I O, Amin, N A, Beekman, M, de Craen, A J M, Degerman, S, Harris, S E, Kan, K-J, Martin-Ruiz, C M, Montgomery, G W, Adolfsson, A N, Reynolds, C A, Samani, N J, Suchiman, H E D, Viljanen, A, von Zglinicki, T, Wright, M J, Hottenga, J-J, Boomsma, D I, Rantanen, T, Kaprio, J A, Nyholt, D R, Martin, N G, Nyberg, L, Adolfsson, R, Kuh, D, Starr, J M, Deary, I J, Slagboom, P E, van Duijn, C M, Codd, V, Pedersen, N L
Publicado 2017

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

por Panoutsopoulou, K, Southam, L, Elliott, K S, Wrayner, N, Zhai, G, Beazley, C, Thorleifsson, G, Arden, N K, Carr, A, Chapman, K, Deloukas, P, Doherty, M, McCaskie, A, Ollier, W E R, Ralston, S H, Spector, T D, Valdes, A M, Wallis, G A, Wilkinson, J M, Arden, E, Battley, K, Blackburn, H, Blanco, F J, Bumpstead, S, Cupples, L A, Day-Williams, A G, Dixon, K, Doherty, S A, Esko, T, Evangelou, E, Felson, D, Gomez-Reino, J J, Gonzalez, A, Gordon, A, Gwilliam, R, Halldorsson, B V, Hauksson, V B, Hofman, A, Hunt, S E, Ioannidis, J P A, Ingvarsson, T, Jonsdottir, I, Jonsson, H, Keen, R, Kerkhof, H J M, Kloppenburg, M G, Koller, N, Lakenberg, N, Lane, N E, Lee, A T, Metspalu, A, Meulenbelt, I, Nevitt, M C, O'Neill, F, Parimi, N, Potter, S C, Rego-Perez, I, Riancho, J A, Sherburn, K, Slagboom, P E, Stefansson, K, Styrkarsdottir, U, Sumillera, M, Swift, D, Thorsteinsdottir, U, Tsezou, A, Uitterlinden, A G, van Meurs, J B J, Watkins, B, Wheeler, M, Mitchell, S, Zhu, Y, Zmuda, J M, Zeggini, E, Loughlin, J
Publicado 2010

Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes

por Albrechtsen, A., Grarup, N., Li, Y., Sparsø, T., Tian, G., Cao, H., Jiang, T., Kim, S. Y., Korneliussen, T., Li, Q., Nie, C., Wu, R., Skotte, L., Morris, A. P., Ladenvall, C., Cauchi, S., Stančáková, A., Andersen, G., Astrup, A., Banasik, K., Bennett, A. J., Bolund, L., Charpentier, G., Chen, Y., Dekker, J. M., Doney, A. S. F., Dorkhan, M., Forsen, T., Frayling, T. M., Groves, C. J., Gui, Y., Hallmans, G., Hattersley, A. T., He, K., Hitman, G. A., Holmkvist, J., Huang, S., Jiang, H., Jin, X., Justesen, J. M., Kristiansen, K., Kuusisto, J., Lajer, M., Lantieri, O., Li, W., Liang, H., Liao, Q., Liu, X., Ma, T., Ma, X., Manijak, M. P., Marre, M., Mokrosiński, J., Morris, A. D., Mu, B., Nielsen, A. A., Nijpels, G., Nilsson, P., Palmer, C. N. A., Rayner, N. W., Renström, F., Ribel-Madsen, R., Robertson, N., Rolandsson, O., Rossing, P., Schwartz, T. W., Slagboom, P. E., Sterner, M., Tang, M., Tarnow, L., Tuomi, T., van’t Riet, E., van Leeuwen, N., Varga, T. V., Vestmar, M. A., Walker, M., Wang, B., Wang, Y., Wu, H., Xi, F., Yengo, L., Yu, C., Zhang, X., Zhang, J., Zhang, Q., Zhang, W., Zheng, H., Zhou, Y., Altshuler, D., ‘t Hart, L. M., Franks, P. W., Balkau, B., Froguel, P., McCarthy, M. I., Laakso, M., Groop, L., Christensen, C., Brandslund, I., Lauritzen, T., Witte, D. R., Linneberg, A., Jørgensen, T., Hansen, T., Wang, J., Nielsen, R., Pedersen, O.
Publicado 2012