Abdominal fat depots associated with insulin resistance and metabolic syndrome risk factors in black African young adults

por De Lucia Rolfe, Emanuella, Ong, Ken K., Sleigh, Alison, Dunger, David B., Norris, Shane A.
Publicado 2015

Simple and effective exercise design for assessing in vivo mitochondrial function in clinical applications using (31)P magnetic resonance spectroscopy

por Sleigh, Alison, Lupson, Victoria, Thankamony, Ajay, Dunger, David B., Savage, David B., Carpenter, T. Adrian, Kemp, Graham J.
Publicado 2016

(31)P magnetization transfer measurements of P(i)→ATP flux in exercising human muscle

por Sleigh, Alison, Savage, David B., Williams, Guy B., Porter, David, Carpenter, T. Adrian, Brindle, Kevin M., Kemp, Graham J.
Publicado 2016

Defective Mitochondrial Function In Vivo in Skeletal Muscle in Adults with Down’s Syndrome: A (31)P-MRS Study

por Phillips, Alexander C., Sleigh, Alison, McAllister, Catherine J., Brage, Soren, Carpenter, T. Adrian, Kemp, Graham J., Holland, Anthony J.
Publicado 2013

Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications

por Stovell, Matthew G., Yan, Jiun-Lin, Sleigh, Alison, Mada, Marius O., Carpenter, T. Adrian, Hutchinson, Peter J. A., Carpenter, Keri L. H.
Publicado 2017

Corrigendum: Assessing Metabolism and Injury in Acute Human Traumatic Brain Injury with Magnetic Resonance Spectroscopy: Current and Future Applications

por Stovell, Matthew G., Yan, Jiun-Lin, Sleigh, Alison, Mada, Marius O., Carpenter, T. Adrian, Hutchinson, Peter J. A., Carpenter, Keri L. H.
Publicado 2017

Compositional marker in vivo reveals intramyocellular lipid turnover during fasting-induced lipolysis

por Thankamony, Ajay, Kemp, Graham J., Koulman, Albert, Bokii, Vlada, Savage, David B., Boesch, Chris, Hodson, Leanne, Dunger, David B., Sleigh, Alison
Publicado 2018

Validity of ultrasonography to assess hepatic steatosis compared to magnetic resonance spectroscopy as a criterion method in older adults

por De Lucia Rolfe, Emanuella, Brage, Soren, Sleigh, Alison, Finucane, Francis, Griffin, Simon J., Wareham, Nick J., Ong, Ken K., Forouhi, Nita G.
Publicado 2018

Dyslipidemia, Insulin Resistance, Ectopic Lipid Accumulation, and Vascular Function in Resistance to Thyroid Hormone β

por Moran, Carla, McEniery, Carmel M, Schoenmakers, Nadia, Mitchell, Catherine, Sleigh, Alison, Watson, Laura, Lyons, Greta, Burling, Keith, Barker, Peter, Chatterjee, Krishna
Publicado 2021

Accumulation of saturated intramyocellular lipid is associated with insulin resistance

por Savage, David B., Watson, Laura, Carr, Katie, Adams, Claire, Brage, Soren, Chatterjee, Krishna K., Hodson, Leanne, Boesch, Chris, Kemp, Graham J., Sleigh, Alison
Publicado 2019

Liver fat accumulation is associated with reduced hepatic insulin extraction and beta cell dysfunction in healthy older individuals

por Finucane, Francis M, Sharp, Stephen J, Hatunic, Mensud, Sleigh, Alison, De Lucia Rolfe, Ema, Aihie Sayer, Avan, Cooper, Cyrus, Griffin, Simon J, Wareham, Nicholas J
Publicado 2014

The metabolic syndrome- associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion

por Rocha, Nuno, Payne, Felicity, Huang-Doran, Isabel, Sleigh, Alison, Fawcett, Katherine, Adams, Claire, Stears, Anna, Saudek, Vladimir, O’Rahilly, Stephen, Barroso, Inês, Semple, Robert K.
Publicado 2017

Constitutive Activation of AKT2 in Humans Leads to Hypoglycemia Without Fatty Liver or Metabolic Dyslipidemia

por Minic, Marina, Rocha, Nuno, Harris, Julie, Groeneveld, Matthijs P., Leiter, Sarah, Wareham, Nicholas, Sleigh, Alison, De Lonlay, Pascale, Hussain, Khalid, O’Rahilly, Stephen, Semple, Robert K.
Publicado 2017

Intrahepatic Lipid Content and Insulin Resistance Are More Strongly Associated with Impaired NEFA Suppression after Oral Glucose Loading Than with Fasting NEFA Levels in Healthy Ol...

por Finucane, Francis M., Sharp, Stephen J., Hatunic, Mensud, Sleigh, Alison, De Lucia Rolfe, Ema, Sayer, Avan Aihie, Cooper, Cyrus, Griffin, Simon J., Savage, David B., Wareham, Nicholas J.
Publicado 2013

Mitochondrial Oxidative Phosphorylation Is Impaired in Patients with Congenital Lipodystrophy

por Sleigh, Alison, Stears, Anna, Thackray, Kerrie, Watson, Laura, Gambineri, Alessandra, Nag, Sath, Campi, V. Irene, Schoenmakers, Nadia, Brage, Soren, Carpenter, T. Adrian, Murgatroyd, Peter R., O'Rahilly, Stephen, Kemp, Graham J., Savage, David B.
Publicado 2012

Randomized controlled trial of the efficacy of aerobic exercise in reducing metabolic risk in healthy older people: The Hertfordshire Physical Activity Trial

por Finucane, Francis M, Horton, Jessica, Purslow, Lisa R, Savage, David B, Brage, Soren, Besson, Hervé, Horton, Kenneth, Rolfe, Ema De Lucia, Sleigh, Alison, Sharp, Stephen J, Martin, Helen J, Sayer, Avan Aihie, Cooper, Cyrus, Ekelund, Ulf, Griffin, Simon J, Wareham, Nicholas J
Publicado 2009

Insulin resistance uncoupled from dyslipidemia due to C-terminal PIK3R1 mutations

por Huang-Doran, Isabel, Tomlinson, Patsy, Payne, Felicity, Gast, Alexandra, Sleigh, Alison, Bottomley, William, Harris, Julie, Daly, Allan, Rocha, Nuno, Rudge, Simon, Clark, Jonathan, Kwok, Albert, Romeo, Stefano, McCann, Emma, Müksch, Barbara, Dattani, Mehul, Zucchini, Stefano, Wakelam, Michael, Foukas, Lazaros C., Savage, David B., Murphy, Rinki, O’Rahilly, Stephen, Barroso, Inês, Semple, Robert K.
Publicado 2016

(31)P magnetic resonance spectroscopy in skeletal muscle: Experts' consensus recommendations

por Meyerspeer, Martin, Boesch, Chris, Cameron, Donnie, Dezortová, Monika, Forbes, Sean C., Heerschap, Arend, Jeneson, Jeroen A.L., Kan, Hermien E., Kent, Jane, Layec, Gwenaël, Prompers, Jeanine J., Reyngoudt, Harmen, Sleigh, Alison, Valkovič, Ladislav, Kemp, Graham J., Baligand, Céline, Carlier, Pierre G., Chatel, Benjamin, Damon, Bruce, Heskamp, Linda, Hájek, Milan, Jooijmans, Melissa, Krssak, Martin, Reichenbach, Juergen, Schmid, Albrecht, Slade, Jill, Vandenborne, Krista, Walter, Glenn A., Willis, David
Publicado 2020

Human biallelic MFN2 mutations induce mitochondrial dysfunction, upper body adipose hyperplasia, and suppression of leptin expression

por Rocha, Nuno, Bulger, David A, Frontini, Andrea, Titheradge, Hannah, Gribsholt, Sigrid Bjerge, Knox, Rachel, Page, Matthew, Harris, Julie, Payne, Felicity, Adams, Claire, Sleigh, Alison, Crawford, John, Gjesing, Anette Prior, Bork-Jensen, Jette, Pedersen, Oluf, Barroso, Inês, Hansen, Torben, Cox, Helen, Reilly, Mary, Rossor, Alex, Brown, Rebecca J, Taylor, Simeon I, McHale, Duncan, Armstrong, Martin, Oral, Elif A, Saudek, Vladimir, O’Rahilly, Stephen, Maher, Eamonn R, Richelsen, Bjørn, Savage, David B, Semple, Robert K
Publicado 2017