Alcohol modulation of G-protein-gated inwardly rectifying potassium channels: from binding to therapeutics

por Bodhinathan, Karthik, Slesinger, Paul A.
Publicado 2014

Dual activation of neuronal G protein-gated inwardly rectifying potassium (GIRK) channels by cholesterol and alcohol

por Glaaser, Ian W., Slesinger, Paul A.
Publicado 2017

A Discrete Alcohol Pocket Involved in GIRK Channel Activation

por Aryal, Prafulla, Dvir, Hay, Choe, Senyon, Slesinger, Paul A.
Publicado 2009

Cell-based reporters reveal in vivo dynamics of dopamine and norepinephrine release in murine cortex

por Muller, Arnaud, Joseph, Victory, Slesinger, Paul A., Kleinfeld, David
Publicado 2014

Organotypic Cerebellar Cultures: Apoptotic Challenges and Detection

por Hurtado de Mendoza, Tatiana, Balana, Bartosz, Slesinger, Paul A., Verma, Inder M.
Publicado 2011

The Role of the Cytoplasmic Pore in Inward Rectification of Kir2.1 Channels

por Kurata, Harley T., Cheng, Wayland W., Arrabit, Christine, Slesinger, Paul A., Nichols, Colin G.
Publicado 2007

Structural insights into GIRK2 channel modulation by cholesterol and PIP(2)

por Mathiharan, Yamuna Kalyani, Glaaser, Ian W., Zhao, Yulin, Robertson, Michael J., Skiniotis, Georgios, Slesinger, Paul A.
Publicado 2021

Ras-Association Domain of Sorting Nexin 27 Is Critical for Regulating Expression of GIRK Potassium Channels

por Balana, Bartosz, Bahima, Laia, Bodhinathan, Karthik, Taura, Jaume J., Taylor, Natalie M., Nettleton, Margaret Y., Ciruela, Francisco, Slesinger, Paul A.
Publicado 2013

Dynamic role of the tether helix in PIP(2)-dependent gating of a G protein–gated potassium channel

por Lacin, Emre, Aryal, Prafulla, Glaaser, Ian W., Bodhinathan, Karthik, Tsai, Eric, Marsh, Nidaa, Tucker, Stephen J., Sansom, Mark S.P., Slesinger, Paul A.
Publicado 2017

Precise Therapeutic Targeting of Distinct NRXN1(+/−) Mutations

por Fernando, Michael B., Fan, Yu, Zhang, Yanchun, Kammourh, Sarah, Murphy, Aleta N., Ghorbani, Sadaf, Onatzevitch, Ryan, Pero, Adriana, Padilla, Christopher, Cao, Lei, Williams, Sarah, Fang, Gang, Slesinger, Paul A., Brennand, Kristen J.
Publicado 2023

Induction of Dopaminergic Neurons for Neuronal Subtype-Specific Modeling of Psychiatric Disease Risk

por Powell, Samuel K., O’Shea, Callan, Townsley, Kayla, Prytkova, Iya, Dobrindt, Kristina, Elahi, Rahat, Iskhakova, Marina, Lambert, Tova, Valada, Aditi, Liao, Will, Ho, Seok-Man, Slesinger, Paul A., Huckins, Laura M., Akbarian, Schahram, Brennand, Kristen J.
Publicado 2023

An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells

por TCW, Julia, Wang, Minghui, Pimenova, Anna A., Bowles, Kathryn R., Hartley, Brigham J., Lacin, Emre, Machlovi, Saima I., Abdelaal, Rawan, Karch, Celeste M., Phatnani, Hemali, Slesinger, Paul A., Zhang, Bin, Goate, Alison M., Brennand, Kristen J.
Publicado 2017

5. Collaborative Study on the Genetics of Alcoholism: Functional genomics

por Gameiro‐Ros, Isabel, Popova, Dina, Prytkova, Iya, Pang, Zhiping P., Liu, Yunlong, Dick, Danielle, Bucholz, Kathleen K., Agrawal, Arpana, Porjesz, Bernice, Goate, Alison M., Xuei, Xiaoling, Kamarajan, Chella, Tischfield, Jay A., Edenberg, Howard J., Slesinger, Paul A., Hart, Ronald P.
Publicado 2023

The collaborative study on the genetics of alcoholism: Genetics

por Johnson, Emma C., Salvatore, Jessica E., Lai, Dongbing, Merikangas, Alison K., Nurnberger, John I., Tischfield, Jay A., Xuei, Xiaoling, Kamarajan, Chella, Wetherill, Leah, Rice, John P., Kramer, John R., Kuperman, Samuel, Foroud, Tatiana, Slesinger, Paul A., Goate, Alison M., Porjesz, Bernice, Dick, Danielle M., Edenberg, Howard J., Agrawal, Arpana
Publicado 2023

Alcohol reverses the effects of KCNJ6 (GIRK2) noncoding variants on excitability of human glutamatergic neurons

por Popova, Dina, Gameiro-Ros, Isabel, Youssef, Mark M., Zalamea, Petronio, Morris, Ayeshia D., Prytkova, Iya, Jadali, Azadeh, Kwan, Kelvin Y., Kamarajan, Chella, Salvatore, Jessica E., Xuei, Xiaoling, Chorlian, David B., Porjesz, Bernice, Kuperman, Samuel, Dick, Danielle M., Goate, Alison, Edenberg, Howard J., Tischfield, Jay A., Pang, Zhiping P., Slesinger, Paul A., Hart, Ronald P.
Publicado 2022

ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex

por Fulton, Sasha L., Bendl, Jaroslav, Gameiro-Ros, Isabel, Fullard, John F., Al-Kachak, Amni, Lepack, Ashley E., Stewart, Andrew F., Singh, Sumnima, Poller, Wolfram C., Bastle, Ryan M., Hauberg, Mads E., Fakira, Amanda K., Chen, Min, Cuttoli, Romain Durand-de, Cathomas, Flurin, Ramakrishnan, Aarthi, Gleason, Kelly, Shen, Li, Tamminga, Carol A., Milosevic, Ana, Russo, Scott J., Swirski, Filip, Blitzer, Robert D., Slesinger, Paul A., Roussos, Panos, Maze, Ian
Publicado 2023

Structure of human GABA(B) receptor in an inactive state

por Park, Jinseo, Fu, Ziao, Frangaj, Aurel, Liu, Jonathan, Mosyak, Lidia, Shen, Tong, Slavkovich, Vesna N., Ray, Kimberly M., Taura, Jaume, Cao, Baohua, Geng, Yong, Zuo, Hao, Kou, Yongjun, Grassucci, Robert, Chen, Shaoxia, Liu, Zheng, Lin, Xin, Williams, Justin P., Rice, William J., Eng, Edward T., Huang, Rick K., Soni, Rajesh K., Kloss, Brian, Yu, Zhiheng, Javitch, Jonathan A., Hendrickson, Wayne A., Slesinger, Paul A., Quick, Matthias, Graziano, Joseph, Yu, Hongtao, Fiehn, Oliver, Clarke, Oliver B., Frank, Joachim, Fan, Qing R.
Publicado 2020