Narrowing the knowledge gaps for melanoma

por Slipicevic, Ana, Herlyn, Meenhard
Publicado 2012

MX2 mediates establishment of interferon response profile, regulates XAF1, and can sensitize melanoma cells to targeted therapy

por Juraleviciute, Marina, Nsengimana, Jérémie, Newton‐Bishop, Julia, Hendriks, Gert J., Slipicevic, Ana
Publicado 2021

Expression of CDK1(Tyr15), pCDK1(Thr161), Cyclin B1 (Total) and pCyclin B1(Ser126) in Vulvar Squamous Cell Carcinoma and Their Relations with Clinicopatological Features and Progno...

por Wang, Zhihui, Slipicevic, Ana, Førsund, Mette, Trope, Claes G., Nesland, Jahn M., Holm, Ruth
Publicado 2015

Cellular localization of CIP2A determines its prognostic impact in superficial spreading and nodular melanoma

por Flørenes, Vivi Ann, Emilsen, Elisabeth, Dong, Hiep Phuc, Førsund, Mette, Holm, Ruth, Slipicevic, Ana
Publicado 2015

Evaluation of CHK1 activation in vulvar squamous cell carcinoma and its potential as a therapeutic target in vitro

por Wang, Zhihui, Førsund, Mette S., Trope, Claes G., Nesland, Jahn M., Holm, Ruth, Slipicevic, Ana
Publicado 2018

Novel Peptide-drug Conjugate Melflufen Efficiently Eradicates Bortezomib-resistant Multiple Myeloma Cells Including Tumor-initiating Myeloma Progenitor Cells

por Byrgazov, Konstantin, Besse, Andrej, Kraus, Marianne, Slipicevic, Ana, Lehmann, Fredrik, Driessen, Christoph, Besse, Lenka
Publicado 2021

High Expression of Wee1 Is Associated with Poor Disease-Free Survival in Malignant Melanoma: Potential for Targeted Therapy

por Magnussen, Gry Irene, Holm, Ruth, Emilsen, Elisabeth, Rosnes, Anne Katrine Ree, Slipicevic, Ana, Flørenes, Vivi Ann
Publicado 2012

The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells

por Slipicevic, Ana, Jørgensen, Kjersti, Skrede, Martina, Rosnes, Anne Katrine Ree, Trøen, Gunhild, Davidson, Ben, Flørenes, Vivi Ann
Publicado 2008

Cytoplasmic BRMS1 expression in malignant melanoma is associated with increased disease-free survival

por Slipicevic, Ana, Holm, Ruth, Emilsen, Elisabeth, Ree Rosnes, Anne Katrine, Welch, Danny R, Mælandsmo, Gunhild M, Flørenes, Vivi Ann
Publicado 2012

Combined inhibition of the cell cycle related proteins Wee1 and Chk1/2 induces synergistic anti-cancer effect in melanoma

por Magnussen, Gry Irene, Emilsen, Elisabeth, Giller Fleten, Karianne, Engesæter, Birgit, Nähse-Kumpf, Viola, Fjær, Roar, Slipicevic, Ana, Flørenes, Vivi Ann
Publicado 2015

Melphalan flufenamide inhibits osteoclastogenesis by suppressing proliferation of monocytes

por Byrgazov, Konstantin, Lind, Thomas, Rasmusson, Annica J., Andersson, Claes, Slipicevic, Ana, Lehmann, Fredrik, Gullbo, Joachim, Melhus, Håkan, Larsson, Rolf, Fryknäs, Mårten
Publicado 2021

P598: DISRUPTION IN ONE-CARBON METABOLISM THROUGH MTHFD1 INHIBITION AS NOVEL THERAPEUTIC STRATEGY IN CHRONIC LYMPHOCYTIC LEUKEMIA

por Viry, Elodie, Duculty, Chloé, Kiweler, Nicole, Pulido, Coralie, Oudin, Anais, Slipicevic, Ana, Henriksson, Martin, Meise, Johannes, Helleday, Thomas, Moussay, Etienne, Paggetti, Jérôme
Publicado 2023

PB2071: SENSITIVITY OF MULTIPLE MYELOMA TO MELFLUFEN ASSOCIATES WITH DECREASED P53 ACTIVITY AND ENRICHMENT OF DNA DAMAGE REPAIR PATHWAY GENES

por Miettinen, Juho, Sergeev, Philipp, Adhikari, Sadiksha, Huppunen, Maiju-Emilia, Suvela, Minna, Slipicevic, Ana, Nupponen, Nina N, Acs, Klara, Lehmann, Fredrik, Heckman, Caroline
Publicado 2023

Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide

por Byrgazov, Konstantin, Anderson, Claes, Salzer, Benjamin, Bozsaky, Eva, Larsson, Rolf, Gullbo, Joachim, Lehner, Manfred, Lehmann, Fredrik, Slipicevic, Ana, Kager, Leo, Fryknäs, Mårten, Taschner-Mandl, Sabine
Publicado 2020

Melflufen, a peptide‐conjugated alkylator, is an efficient anti‐neo‐plastic drug in breast cancer cell lines

por Schepsky, Alexander, Traustadottir, Gunnhildur Asta, Joelsson, Jon Petur, Ingthorsson, Sævar, Kricker, Jennifer, Bergthorsson, Jon Thor, Asbjarnarson, Arni, Gudjonsson, Thorkell, Nupponen, Nina, Slipicevic, Ana, Lehmann, Fredrik, Gudjonsson, Thorarinn
Publicado 2020

Growth Response and Differentiation of Bone Marrow-Derived Mesenchymal Stem/Stromal Cells in the Presence of Novel Multiple Myeloma Drug Melflufen

por Gebraad, Arjen, Ohlsbom, Roope, Miettinen, Juho J., Emeh, Promise, Pakarinen, Toni-Karri, Manninen, Mikko, Eskelinen, Antti, Kuismanen, Kirsi, Slipicevic, Ana, Lehmann, Fredrik, Nupponen, Nina N., Heckman, Caroline A., Miettinen, Susanna
Publicado 2022

The Peptide–Drug Conjugate Melflufen Modulates the Unfolded Protein Response of Multiple Myeloma and Amyloidogenic Plasma Cells and Induces Cell Death

por Flanagan, Ken, Kumari, Romika, Miettinen, Juho J., Haney, Staci L., Varney, Michelle L., Williams, Jacob T., Majumder, Muntasir M., Suvela, Minna, Slipicevic, Ana, Lehmann, Fredrik, Nupponen, Nina N., Holstein, Sarah A., Heckman, Caroline A.
Publicado 2022

Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells

por Li, Xiaoran, Lu, Jie, Kan, Quancheng, Li, Xiaoli, Fan, Qiong, Li, Yaqing, Huang, Ruixia, Slipicevic, Ana, Dong, Hiep Phuc, Eide, Lars, Wang, Junbai, Zhang, Hongquan, Berge, Viktor, Goscinski, Mariusz Adam, Kvalheim, Gunnar, Nesland, Jahn M., Suo, Zhenhe
Publicado 2017

Aminopeptidase Expression in Multiple Myeloma Associates with Disease Progression and Sensitivity to Melflufen

por Miettinen, Juho J., Kumari, Romika, Traustadottir, Gunnhildur Asta, Huppunen, Maiju-Emilia, Sergeev, Philipp, Majumder, Muntasir M., Schepsky, Alexander, Gudjonsson, Thorarinn, Lievonen, Juha, Bazou, Despina, Dowling, Paul, O`Gorman, Peter, Slipicevic, Ana, Anttila, Pekka, Silvennoinen, Raija, Nupponen, Nina N., Lehmann, Fredrik, Heckman, Caroline A.
Publicado 2021

Formate overflow drives toxic folate trapping in MTHFD1 inhibited cancer cells

por Green, Alanna C., Marttila, Petra, Kiweler, Nicole, Chalkiadaki, Christina, Wiita, Elisée, Cookson, Victoria, Lesur, Antoine, Eiden, Kim, Bernardin, François, Vallin, Karl S. A., Borhade, Sanjay, Long, Maeve, Ghahe, Elahe Kamali, Jiménez-Alonso, Julio J., Jemth, Ann-Sofie, Loseva, Olga, Mortusewicz, Oliver, Meyers, Marianne, Viry, Elodie, Johansson, Annika I., Hodek, Ondřej, Homan, Evert, Bonagas, Nadilly, Ramos, Louise, Sandberg, Lars, Frödin, Morten, Moussay, Etienne, Slipicevic, Ana, Letellier, Elisabeth, Paggetti, Jérôme, Sørensen, Claus Storgaard, Helleday, Thomas, Henriksson, Martin, Meiser, Johannes
Publicado 2023