Deciphering the hierarchy of angiohematopoietic progenitors from human pluripotent stem cells

por Slukvin, Igor I.
Publicado 2013

CRISPR/Cas9 genome editing to create nonhuman primate models for studying stem cell therapies for HIV infection

por Schmidt, Jenna Kropp, Reynolds, Matthew R., Golos, Thaddeus G., Slukvin, Igor I.
Publicado 2022

A Defined, Feeder-Free, Serum-Free System to Generate In Vitro Hematopoietic Progenitors and Differentiated Blood Cells from hESCs and hiPSCs

por Salvagiotto, Giorgia, Burton, Sarah, Daigh, Christine A., Rajesh, Deepika, Slukvin, Igor I., Seay, Nicholas J.
Publicado 2011

UM171 expands distinct types of myeloid and NK progenitors from human pluripotent stem cells

por Mesquitta, Walatta-Tseyon, Wandsnider, Matthew, Kang, HyunJun, Thomson, James, Moskvin, Oleg, Suknuntha, Kran, Slukvin, Igor I.
Publicado 2019

GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells

por D'Souza, Saritha S., Maufort, John, Kumar, Akhilesh, Zhang, Jiuchun, Smuga-Otto, Kimberley, Thomson, James A., Slukvin, Igor I.
Publicado 2016

GATA2 Is Dispensable for Specification of Hemogenic Endothelium but Promotes Endothelial-to-Hematopoietic Transition

por Kang, HyunJun, Mesquitta, Walatta-Tseyon, Jung, Ho Sun, Moskvin, Oleg V., Thomson, James A., Slukvin, Igor I.
Publicado 2018

Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits

por Schmidt, Jenna Kropp, Kim, Yun Hee, Strelchenko, Nick, Gierczic, Sarah R., Pavelec, Derek, Golos, Thaddeus G., Slukvin, Igor I.
Publicado 2023

Nonirradiated NOD,B6.SCID Il2rγ(−/−)Kit(W41/W41) (NBSGW) Mice Support Multilineage Engraftment of Human Hematopoietic Cells

por McIntosh, Brian E., Brown, Matthew E., Duffin, Bret M., Maufort, John P., Vereide, David T., Slukvin, Igor I., Thomson, James A.
Publicado 2015

Brown-like adipose progenitors derived from human induced pluripotent stem cells: Identification of critical pathways governing their adipogenic capacity

por Hafner, Anne-Laure, Contet, Julian, Ravaud, Christophe, Yao, Xi, Villageois, Phi, Suknuntha, Kran, Annab, Karima, Peraldi, Pascal, Binetruy, Bernard, Slukvin, Igor I., Ladoux, Annie, Dani, Christian
Publicado 2016

Specification and Diversification of Pericytes and Smooth Muscle Cells from Mesenchymoangioblasts

por Kumar, Akhilesh, D’Souza, Saritha Sandra, Moskvin, Oleg V., Toh, Huishi, Wang, Bowen, Zhang, Jue, Swanson, Scott, Guo, Lian-Wang, Thomson, James A., Slukvin, Igor I.
Publicado 2017

Genome editing of CCR5 by CRISPR-Cas9 in Mauritian cynomolgus macaque embryos

por Schmidt, Jenna Kropp, Strelchenko, Nick, Park, Mi Ae, Kim, Yun Hee, Mean, Katherine D., Schotzko, Michele L., Kang, Hyun Jun, Golos, Thaddeus G., Slukvin, Igor I.
Publicado 2020

SOX17 integrates HOXA and arterial programs in hemogenic endothelium to drive definitive lympho-myeloid hematopoiesis

por Jung, Ho Sun, Uenishi, Gene, Park, Mi Ae, Liu, Peng, Suknuntha, Kran, Raymond, Matthew, Choi, Yoon Jung, Thomson, James A., Ong, Irene M., Slukvin, Igor I.
Publicado 2021

SOX18-enforced expression diverts hemogenic endothelium-derived progenitors from T towards NK lymphoid pathways

por Jung, Ho Sun, Suknuntha, Kran, Kim, Yun Hee, Liu, Peng, Dettle, Samuel T., Sedzro, Divine Mensah, Smith, Portia R., Thomson, James A., Ong, Irene M., Slukvin, Igor I.
Publicado 2023

Assessment of safety and immunogenicity of MHC homozygous iPSC-derived CD34(+) hematopoietic progenitors in an NHP model

por D’Souza, Saritha S., Kumar, Akhilesh, Maufort, John, Weinfurter, Jason T., Raymond, Matthew, Strelchenko, Nick S., Perrin, Elizabeth, Coonen, Jennifer, Mejia, Andres, Simmons, Heather A., Torbett, Bruce E., Reynolds, Matthew, Thomson, James A., Slukvin, Igor I.
Publicado 2022

Allogeneic MHC-matched T-cell receptor α/β-depleted bone marrow transplants in SHIV-infected, ART-suppressed Mauritian cynomolgus macaques

por Weinfurter, Jason T., D’Souza, Saritha S., Matschke, Lea M., Bennett, Sarah, Kelnhofer-Millevolte, Laurel E., Suknuntha, Kran, Kumar, Akhilesh, Coonen, Jennifer, Capitini, Christian M., Hematti, Peiman, Golos, Thaddeus G., Slukvin, Igor I., Reynolds, Matthew R.
Publicado 2022

Generation of anti-GD2 CAR macrophages from human pluripotent stem cells for cancer immunotherapies

por Zhang, Jue, Webster, Sarah, Duffin, Bret, Bernstein, Matthew N., Steill, John, Swanson, Scott, Forsberg, Matthew H., Bolin, Jennifer, Brown, Matthew E., Majumder, Aditi, Capitini, Christian M., Stewart, Ron, Thomson, James A., Slukvin, Igor I.
Publicado 2023

Cymerus™ iPSC-MSCs significantly prolong survival in a pre-clinical, humanized mouse model of Graft-vs-host disease

por Ozay, E. Ilker, Vijayaraghavan, Jyothi, Gonzalez-Perez, Gabriela, Shanthalingam, Sudarvili, Sherman, Heather L., Garrigan, Daniel T., Chandiran, Karthik, Torres, Joe A., Osborne, Barbara A., Tew, Gregory N., Slukvin, Igor I., Macdonald, Ross A., Kelly, Kilian, Minter, Lisa M.
Publicado 2019

NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells

por Uenishi, Gene I., Jung, Ho Sun, Kumar, Akhilesh, Park, Mi Ae, Hadland, Brandon K., McLeod, Ethan, Raymond, Matthew, Moskvin, Oleg, Zimmerman, Catherine E., Theisen, Derek J., Swanson, Scott, J. Tamplin, Owen, Zon, Leonard I., Thomson, James A., Bernstein, Irwin D., Slukvin, Igor I.
Publicado 2018