The concept of gene therapy for glaucoma: the dream that has not come true yet

por Sulak, Robert, Liu, Xiaonan, Smedowski, Adrian
Publicado 2023

Atypical Regressive Corneal Endothelial Cysts in Long-Term Confocal Follow-Up: A Case Report

por Smedowski, Adrian, Wylegala, Edward, Wojcik, Lukasz, Tarnawska, Dorota
Publicado 2015

A rat experimental model of glaucoma incorporating rapid-onset elevation of intraocular pressure

por Smedowski, Adrian, Pietrucha-Dutczak, Marita, Kaarniranta, Kai, Lewin-Kowalik, Joanna
Publicado 2014

Molecular Mechanisms Underlying Age-Related Ocular Diseases

por Amadio, Marialaura, Kaarniranta, Kai, Xu, Heping, Smedowski, Adrian, Ferrington, Deborah A.
Publicado 2018

The Role of Endogenous Neuroprotective Mechanisms in the Prevention of Retinal Ganglion Cells Degeneration

por Pietrucha-Dutczak, Marita, Amadio, Marialaura, Govoni, Stefano, Lewin-Kowalik, Joanna, Smedowski, Adrian
Publicado 2018

Metallothioneins, a Part of the Retinal Endogenous Protective System in Various Ocular Diseases

por Jamrozik, Daniel, Dutczak, Radosław, Machowicz, Joanna, Wojtyniak, Alicja, Smędowski, Adrian, Pietrucha-Dutczak, Marita
Publicado 2023

Predegenerated Schwann cells–a novel prospect for cell therapy for glaucoma: neuroprotection, neuroregeneration and neuroplasticity

por Smedowski, Adrian, Liu, Xiaonan, Pietrucha-Dutczak, Marita, Matuszek, Iwona, Varjosalo, Markku, Lewin-Kowalik, Joanna
Publicado 2016

Candidate proteins from predegenerated nerve exert time-specific protection of retinal ganglion cells in glaucoma

por Pietrucha-Dutczak, Marita, Smedowski, Adrian, Liu, Xiaonan, Matuszek, Iwona, Varjosalo, Markku, Lewin-Kowalik, Joanna
Publicado 2017

FluoroGold-Labeled Organotypic Retinal Explant Culture for Neurotoxicity Screening Studies

por Smedowski, Adrian, Pietrucha-Dutczak, Marita, Maniar, Ruchi, Ajeleti, Michael, Matuszek, Iwona, Lewin-Kowalik, Joanna
Publicado 2018

Surgical Menopause Impairs Retinal Conductivity and Worsens Prognosis in an Acute Model of Rat Optic Neuropathy

por Olakowska, Edyta, Rodak, Piotr, Pacwa, Anna, Machowicz, Joanna, Machna, Bartosz, Lewin-Kowalik, Joanna, Smedowski, Adrian
Publicado 2022

Rodent Models of Diabetic Retinopathy as a Useful Research Tool to Study Neurovascular Cross-Talk

por Polewik, Karolina, Kosek, Maciej, Jamrozik, Daniel, Matuszek, Iwona, Smędowski, Adrian, Lewin-Kowalik, Joanna, Pietrucha-Dutczak, Marita
Publicado 2023

A unique pre-endothelial layer at the posterior peripheral cornea: ultrastructural study

por Akhtar, Saeed, Samivel, Ramachandran, Smedowski, Adrian, Alkanaan, Aljoharah, Masmali, Ali, Kirat, Omar, Khan, Adnan Ali, Almubrad, Turki
Publicado 2022

Different Impacts of Luminosity on Contrast Vision in Eyes with Transparent Optic Media and with Cataract Simulation

por Smedowski, Adrian, Mikus-Zagorska, Karolina, Jakubowska, Agnieszka, Piotrowska-Gwozdz, Anna, Piotrowska-Seweryn, Agnieszka, Orchel, Patrycja, Pojda-Wilczek, Dorota
Publicado 2015

Ultrastructural study of collagen fibrils, proteoglycans and lamellae of the cornea treated with iontophoresis – UVA cross-linking and hypotonic riboflavin solution

por Almubrad, Turki, Mencucci, Rita, Smedowski, Adrian, Samivel, Ramachandran, Almutleb, Essam, Alkanaan, Aljoharah, Khan, Adnan Ali, Masmali, Ali, Akhtar, Saeed
Publicado 2021

Deficiency of the RNA-binding protein ELAVL1/HuR leads to the failure of endogenous and exogenous neuroprotection of retinal ganglion cells

por Pacwa, Anna, Machowicz, Joanna, Akhtar, Saeed, Rodak, Piotr, Liu, Xiaonan, Pietrucha-Dutczak, Marita, Lewin-Kowalik, Joanna, Amadio, Marialaura, Smedowski, Adrian
Publicado 2023

SCD1-Fatty Acid Desaturase Inhibitor MF-438 Alleviates Latent Inflammation Induced by Preservative-Free Prostaglandin Analog Eye Drops

por Pacwa, Anna, Machowicz, Joanna, Wojtyniak, Alicja, Pietrucha-Dutczak, Marita, Toropainen, Elisa, Koskela, Ali, Mrukwa-Kominek, Ewa, Lewin-Kowalik, Joanna, Smedowski, Adrian
Publicado 2022

Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells

por Koskela, Ali, Manai, Federico, Basagni, Filippo, Liukkonen, Mikko, Rosini, Michela, Govoni, Stefano, Monte, Massimo Dal, Smedowski, Adrian, Kaarniranta, Kai, Amadio, Marialaura
Publicado 2022

Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38(MAPK), and JNK Kinase Pathways

por Marchesi, Nicoletta, Thongon, Natthakan, Pascale, Alessia, Provenzani, Alessandro, Koskela, Ali, Korhonen, Eveliina, Smedowski, Adrian, Govoni, Stefano, Kauppinen, Anu, Kaarniranta, Kai, Amadio, Marialaura
Publicado 2018

Electrical synapses interconnecting axons revealed in the optic nerve head – a novel model of gap junctions’ involvement in optic nerve function

por Smedowski, Adrian, Akhtar, Saeed, Liu, Xiaonan, Pietrucha‐Dutczak, Marita, Podracka, Lucia, Toropainen, Elisa, Alkanaan, Aljoharah, Ruponen, Marika, Urtti, Arto, Varjosalo, Markku, Kaarniranta, Kai, Lewin‐Kowalik, Joanna
Publicado 2019

Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration

por Felszeghy, Szabolcs, Viiri, Johanna, Paterno, Jussi J., Hyttinen, Juha M.T., Koskela, Ali, Chen, Mei, Leinonen, Henri, Tanila, Heikki, Kivinen, Niko, Koistinen, Arto, Toropainen, Elisa, Amadio, Marialaura, Smedowski, Adrian, Reinisalo, Mika, Winiarczyk, Mateusz, Mackiewicz, Jerzy, Mutikainen, Maija, Ruotsalainen, Anna-Kaisa, Kettunen, Mikko, Jokivarsi, Kimmo, Sinha, Debasish, Kinnunen, Kati, Petrovski, Goran, Blasiak, Janusz, Bjørkøy, Geir, Koskelainen, Ari, Skottman, Heli, Urtti, Arto, Salminen, Antero, Kannan, Ram, Ferrington, Deborah A., Xu, Heping, Levonen, Anna-Liisa, Tavi, Pasi, Kauppinen, Anu, Kaarniranta, Kai
Publicado 2018