Development and application of a pediatric mechanistic kidney model

por Salem, Farzaneh, Small, Ben G., Johnson, Trevor N.
Publicado 2022

Increasing application of pediatric physiologically based pharmacokinetic models across academic and industry organizations

por Johnson, Trevor N., Small, Ben G., Rowland Yeo, Karen
Publicado 2022

Physiologically Based Pharmacokinetic Modelling to Predict Imatinib Exposures in Cancer Patients with Renal Dysfunction: A Case Study

por Rowland Yeo, Karen, Hatley, Oliver, Small, Ben G., Johnson, Trevor N.
Publicado 2023

A best practice framework for applying physiologically‐based pharmacokinetic modeling to pediatric drug development

por Johnson, Trevor N., Small, Ben G., Berglund, Eva Gil, Rowland Yeo, Karen
Publicado 2021

Integration of Omics Data Sources to Inform Mechanistic Modeling of Immune‐Oncology Therapies: A Tutorial for Clinical Pharmacologists

por Lazarou, Georgia, Chelliah, Vijayalakshmi, Small, Ben G., Walker, Michael, van der Graaf, Piet H., Kierzek, Andrzej M.
Publicado 2020

Efficient discovery of anti-inflammatory small molecule combinations using evolutionary computing

por Small, Ben G, McColl, Barry W, Allmendinger, Richard, Pahle, Jürgen, López-Castejón, Gloria, Rothwell, Nancy J, Knowles, Joshua, Mendes, Pedro, Brough, David, Kell, Douglas B
Publicado 2011

A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins

por Kierzek, Andrzej M., Hickling, Timothy P., Figueroa, Isabel, Kalvass, J. Cory, Nijsen, Marjoleen, Mohan, Krithika, Veldman, Geertruida M., Yamada, Akihiro, Sayama, Hiroyuki, Yokoo, Sachiko, Gulati, Abhishek, Dhanikula, Renu S., Gokemeijer, Jochem, Leil, Tarek A., Thalhauser, Craig J., Giorgi, Mario, Swat, Maciej J., Chelliah, Vijayalakshmi, Small, Ben G., Benson, Neil, Walker, Michael, Gadkar, Kapil, Quarmby, Valerie, Deng, Rong, Ferrante, Andrea, Dickinson, Gemma L., Van Der Walt, Jan‐Stefan, Zhou, Lian, Chen, Xiaoying, Jones, Hannah M., Narula, Jatin, Tourdot, Sophie, Lavé, Thierry, Ribba, Benjamin, van der Graaf, Piet H.
Publicado 2019