IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages

por Smallie, Tim, Ricchetti, Giuseppe, Horwood, Nicole J., Feldmann, Marc, Clark, Andrew R., Williams, Lynn M.
Publicado 2010

Bruton's tyrosine kinase regulates TLR7/8-induced TNF transcription via nuclear factor-κB recruitment

por Page, Theresa H., Urbaniak, Anna M., Espirito Santo, Ana I., Danks, Lynett, Smallie, Timothy, Williams, Lynn M., Horwood, Nicole J.
Publicado 2018

Expression of chemokines CXCL4 and CXCL7 by synovial macrophages defines an early stage of rheumatoid arthritis

por Yeo, L, Adlard, N, Biehl, M, Juarez, M, Smallie, T, Snow, M, Buckley, C D, Raza, K, Filer, A, Scheel-Toellner, D
Publicado 2016

Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E(2), dual specificity phosphatase 1 and tristetraprolin

por Tang, Tina, Scambler, Thomas E., Smallie, Tim, Cunliffe, Helen E., Ross, Ewan A., Rosner, Dalya R., O’Neil, John D., Clark, Andrew R.
Publicado 2017

Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to Lipopolysaccharide

por Smallie, Tim, Ross, Ewan A., Ammit, Alaina J., Cunliffe, Helen E., Tang, Tina, Rosner, Dalya R., Ridley, Michael L., Buckley, Christopher D., Saklatvala, Jeremy, Dean, Jonathan L., Clark, Andrew R.
Publicado 2015

Gain-of-Function Mutation of Tristetraprolin Impairs Negative Feedback Control of Macrophages In Vitro yet Has Overwhelmingly Anti-Inflammatory Consequences In Vivo

por O'Neil, John D., Ross, Ewan A., Ridley, Michael L., Ding, Qize, Tang, Tina, Rosner, Dalya R., Crowley, Thomas, Malhi, Deepak, Dean, Jonathan L., Smallie, Tim, Buckley, Christopher D., Clark, Andrew R.
Publicado 2017

Dominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin

por Ross, Ewan A., Smallie, Tim, Ding, Qize, O’Neil, John D., Cunliffe, Helen E., Tang, Tina, Rosner, Dalya R., Klevernic, Iva, Morrice, Nicholas A., Monaco, Claudia, Cunningham, Adam F., Buckley, Christopher D., Saklatvala, Jeremy, Dean, Jonathan L., Clark, Andrew R.
Publicado 2015

Treatment of inflammatory arthritis via targeting of tristetraprolin, a master regulator of pro-inflammatory gene expression

por Ross, E A, Naylor, A J, O'Neil, J D, Crowley, T, Ridley, M L, Crowe, J, Smallie, T, Tang, T J, Turner, J D, Norling, L V, Dominguez, S, Perlman, H, Verrills, N M, Kollias, G, Vitek, M P, Filer, A, Buckley, C D, Dean, J L, Clark, A R
Publicado 2017