Monitoring the transition of patients on biologics in rheumatoid arthritis: Consensus guidance for pharmacists

por Choquette, Denis, Chan, Jonathan, Bardi, Mohammad, Whiskin, Carolyn, Torani, Gabriel, Smith, Brennan K., Sihota, Aaron
Publicado 2021

Insulin Injection Practices in a Population of Canadians with Diabetes: An Observational Study

por Bari, Basel, Corbeil, Marie-Andrée, Farooqui, Hena, Menzies, Stuart, Pflug, Brian, Smith, Brennan K., Vasquez, Arthur, Berard, Lori
Publicado 2020

Rapid Repression of ADP Transport by Palmitoyl-CoA Is Attenuated by Exercise Training in Humans: A Potential Mechanism to Decrease Oxidative Stress and Improve Skeletal Muscle Insu...

por Ludzki, Alison, Paglialunga, Sabina, Smith, Brennan K., Herbst, Eric A.F., Allison, Mary K., Heigenhauser, George J., Neufer, P. Darrell, Holloway, Graham P.
Publicado 2015

The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration

por Villani, Linda A., Smith, Brennan K., Marcinko, Katarina, Ford, Rebecca J., Broadfield, Lindsay A., Green, Alex E., Houde, Vanessa P., Muti, Paola, Tsakiridis, Theodoros, Steinberg, Gregory R.
Publicado 2016

The AMPK activator R419 improves exercise capacity and skeletal muscle insulin sensitivity in obese mice

por Marcinko, Katarina, Bujak, Adam L., Lally, James S.V., Ford, Rebecca J., Wong, Tammy H., Smith, Brennan K., Kemp, Bruce E., Jenkins, Yonchu, Li, Wei, Kinsella, Todd M., Hitoshi, Yasumichi, Steinberg, Gregory R.
Publicado 2015

Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

por Pinkosky, Stephen L., Newton, Roger S., Day, Emily A., Ford, Rebecca J., Lhotak, Sarka, Austin, Richard C., Birch, Carolyn M., Smith, Brennan K., Filippov, Sergey, Groot, Pieter H.E., Steinberg, Gregory R., Lalwani, Narendra D.
Publicado 2016

Salsalate reduces atherosclerosis through AMPKβ1 in mice

por Day, Emily A., Ford, Rebecca J., Smith, Brennan K., Houde, Vanessa P., Stypa, Stephanie, Rehal, Sonia, Lhotak, Sarka, Kemp, Bruce E., Trigatti, Bernardo L., Werstuck, Geoff H., Austin, Richard C., Fullerton, Morgan D., Steinberg, Gregory R.
Publicado 2021

The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids

por Desjardins, Eric M., Smith, Brennan K., Day, Emily A., Ducommun, Serge, Sanders, Matthew J., Nederveen, Joshua P., Ford, Rebecca J., Pinkosky, Stephen L., Townsend, Logan K., Gutgesell, Robert M., Lu, Rachel, Sakamoto, Kei, Steinberg, Gregory R.
Publicado 2022

Maternal obesity alters fatty acid oxidation, AMPK activity, and associated DNA methylation in mesenchymal stem cells from human infants

por Boyle, Kristen E., Patinkin, Zachary W., Shapiro, Allison L.B., Bader, Carly, Vanderlinden, Lauren, Kechris, Katerina, Janssen, Rachel C., Ford, Rebecca J., Smith, Brennan K., Steinberg, Gregory R., Davidson, Elizabeth J., Yang, Ivana V., Dabelea, Dana, Friedman, Jacob E.
Publicado 2017

The Pesticide Chlorpyrifos Promotes Obesity by Inhibiting Diet-Induced Thermogenesis

por Wang, Bo, Zhang, Shuman, Llanos, Andrea, Tsakiridis, Evangelia E, Desjardins, Eric M, Yabut, Julian M, Green, Alexander E, Day, Emily A, Smith, Brennan K, Lally, James S V, Raphenya, Amogelang R, Srinivasan, Krishna A, McArthur, Andrew G, Kajimura, Shingo, Patel, Jagdish Suresh, Wade, Michael Gordon, Morrison, Katherine Mary, Holloway, Alison, Steinberg, Gregory R
Publicado 2021

Consensus‐based recommendations for titrating cannabinoids and tapering opioids for chronic pain control

por Sihota, Aaron, Smith, Brennan K., Ahmed, Sana‐Ara, Bell, Alan, Blain, Allison, Clarke, Hance, Cooper, Ziva D., Cyr, Claude, Daeninck, Paul, Deshpande, Amol, Ethans, Karen, Flusk, David, Le Foll, Bernard, Milloy, M‐J, Moulin, Dwight E., Naidoo, Vernon, Ong, May, Perez, Jordi, Rod, Kevin, Sealey, Robert, Sulak, Dustin, Walsh, Zachary, O’Connell, Colleen
Publicado 2020

Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1-isoforms

por Pinkosky, Stephen L., Scott, John W., Desjardins, Eric M., Smith, Brennan K., Day, Emily A., Ford, Rebecca J., Langendorf, Christopher G., Ling, Naomi X. Y., Nero, Tracy L., Loh, Kim, Galic, Sandra, Hoque, Ashfaqul, Smiles, William J., Ngoei, Kevin R.W., Parker, Michael W., Yan, Yan, Melcher, Karsten, Kemp, Bruce E., Oakhill, Jonathan S., Steinberg, Gregory R.
Publicado 2020

Consensus recommendations on dosing and administration of medical cannabis to treat chronic pain: results of a modified Delphi process

por Bhaskar, Arun, Bell, Alan, Boivin, Michael, Briques, Wellington, Brown, Matthew, Clarke, Hance, Cyr, Claude, Eisenberg, Elon, de Oliveira Silva, Ricardo Ferreira, Frohlich, Eva, Georgius, Peter, Hogg, Malcolm, Horsted, Tina Ingrid, MacCallum, Caroline A., Müller-Vahl, Kirsten R., O’Connell, Colleen, Sealey, Robert, Seibolt, Marc, Sihota, Aaron, Smith, Brennan K., Sulak, Dustin, Vigano, Antonio, Moulin, Dwight E.
Publicado 2021

The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue

por Wang, Bo, Tsakiridis, Evangelia E., Zhang, Shuman, Llanos, Andrea, Desjardins, Eric M., Yabut, Julian M., Green, Alexander E., Day, Emily A., Smith, Brennan K., Lally, James S. V., Wu, Jianhan, Raphenya, Amogelang R., Srinivasan, Krishna A., McArthur, Andrew G., Kajimura, Shingo, Patel, Jagdish Suresh, Wade, Michael G., Morrison, Katherine M., Holloway, Alison C., Steinberg, Gregory R.
Publicado 2021

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

por Esquejo, Ryan M., Salatto, Christopher T., Delmore, Jake, Albuquerque, Bina, Reyes, Allan, Shi, Yuji, Moccia, Rob, Cokorinos, Emily, Peloquin, Matthew, Monetti, Mara, Barricklow, Jason, Bollinger, Eliza, Smith, Brennan K., Day, Emily A., Nguyen, Chuong, Geoghegan, Kieran F., Kreeger, John M., Opsahl, Alan, Ward, Jessica, Kalgutkar, Amit S., Tess, David, Butler, Lynne, Shirai, Norimitsu, Osborne, Timothy F., Steinberg, Gregory R., Birnbaum, Morris J., Cameron, Kimberly O., Miller, Russell A.
Publicado 2018