Intron retention as a component of regulated gene expression programs

por Jacob, Aishwarya G., Smith, Christopher W. J.
Publicado 2017

Crossregulation and Functional Redundancy between the Splicing Regulator PTB and Its Paralogs nPTB and ROD1

por Spellman, Rachel, Llorian, Miriam, Smith, Christopher W.J.
Publicado 2007

Expression of Human nPTB Is Limited by Extreme Suboptimal Codon Content

por Robinson, Fiona, Jackson, Richard J., Smith, Christopher W. J.
Publicado 2008

Genome-Wide Association between Branch Point Properties and Alternative Splicing

por Corvelo, André, Hallegger, Martina, Smith, Christopher W. J., Eyras, Eduardo
Publicado 2010

The organization of RNA contacts by PTB for regulation of FAS splicing

por Mickleburgh, Ian, Kafasla, Panagiota, Cherny, Dmitry, Llorian, Miriam, Curry, Stephen, Jackson, Richard J., Smith, Christopher W.J.
Publicado 2014

Cell-type specific regulator RBPMS switches alternative splicing via higher-order oligomerization and heterotypic interactions with other splicing regulators

por Yang, Yi, Lee, Giselle C, Nakagaki-Silva, Erick, Huang, Yuling, Peacey, Matthew, Partridge, Ruth, Gooding, Clare, Smith, Christopher W J
Publicado 2023

Stoichiometry of a regulatory splicing complex revealed by single-molecule analyses

por Cherny, Dmitry, Gooding, Clare, Eperon, Giles E, Coelho, Miguel B, Bagshaw, Clive R, Smith, Christopher W J, Eperon, Ian C
Publicado 2010

Crystallographic Analysis of Polypyrimidine Tract-Binding Protein-Raver1 Interactions Involved in Regulation of Alternative Splicing

por Joshi, Amar, Coelho, Miguel B., Kotik-Kogan, Olga, Simpson, Peter J., Matthews, Stephen J., Smith, Christopher W.J., Curry, Stephen
Publicado 2011

Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation

por Tan, Lit-Yeen, Whitfield, Peter, Llorian, Miriam, Monzon-Casanova, Elisa, Diaz-Munoz, Manuel D., Turner, Martin, Smith, Christopher W.J.
Publicado 2015

Phosphorylation of the smooth muscle master splicing regulator RBPMS regulates its splicing activity

por Barnhart, Michael D, Yang, Yi, Nakagaki-Silva, Erick E, Hammond, Thomas H, Pizzinga, Mariavittoria, Gooding, Clare, Stott, Katherine, Smith, Christopher W J
Publicado 2022

MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3

por Gooding, Clare, Edge, Christopher, Lorenz, Mike, Coelho, Miguel B., Winters, Mikael, Kaminski, Clemens F., Cherny, Dmitry, Eperon, Ian C., Smith, Christopher W.J.
Publicado 2013

A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties

por Star, Eleanor, Stevens, Megan, Gooding, Clare, Smith, Christopher W. J., Li, Ling, Ayine, Monica Lamici, Harper, Steve J., Bates, David O., Oltean, Sebastian
Publicado 2021

Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells

por D'Angeli, Vanessa, Monzón‐Casanova, Elisa, Matheson, Louise S., Gizlenci, Özge, Petkau, Georg, Gooding, Clare, Berrens, Rebecca V., Smith, Christopher W. J., Turner, Martin
Publicado 2022

Myocardin regulates exon usage in smooth muscle cells through induction of splicing regulatory factors

por Liu, Li, Kryvokhyzha, Dmytro, Rippe, Catarina, Jacob, Aishwarya, Borreguero-Muñoz, Andrea, Stenkula, Karin G., Hansson, Ola, Smith, Christopher W. J., Fisher, Steven A., Swärd, Karl
Publicado 2022

The alternative splicing program of differentiated smooth muscle cells involves concerted non-productive splicing of post-transcriptional regulators

por Llorian, Miriam, Gooding, Clare, Bellora, Nicolas, Hallegger, Martina, Buckroyd, Adrian, Wang, Xiao, Rajgor, Dipen, Kayikci, Melis, Feltham, Jack, Ule, Jernej, Eyras, Eduardo, Smith, Christopher W.J.
Publicado 2016

The RNA binding protein PTBP1 is necessary for B cell selection in germinal centers

por Monzón-Casanova, Elisa, Screen, Michael, Díaz-Muñoz, Manuel D., Coulson, Richard M. R., Bell, Sarah E., Lamers, Greta, Solimena, Michele, Smith, Christopher W.J., Turner, Martin
Publicado 2018

Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing

por Attig, Jan, Agostini, Federico, Gooding, Clare, Chakrabarti, Anob M., Singh, Aarti, Haberman, Nejc, Zagalak, Julian A., Emmett, Warren, Smith, Christopher W.J., Luscombe, Nicholas M., Ule, Jernej
Publicado 2018

SRSF3 maintains transcriptome integrity in oocytes by regulation of alternative splicing and transposable elements

por Do, Dang Vinh, Strauss, Bernhard, Cukuroglu, Engin, Macaulay, Iain, Wee, Keng Boon, Hu, Tim Xiaoming, Igor, Ruiz De Los Mozos, Lee, Caroline, Harrison, Andrew, Butler, Richard, Dietmann, Sabine, Jernej, Ule, Marioni, John, Smith, Christopher W. J., Göke, Jonathan, Surani, M. Azim
Publicado 2018

A systems view of spliceosomal assembly and branchpoints with iCLIP

por Briese, Michael, Haberman, Nejc, Sibley, Christopher R., Faraway, Rupert, Elser, Andrea S., Chakrabarti, Anob M., Wang, Zhen, König, Julian, Perera, David, Wickramasinghe, Vihandha O., Venkitaraman, Ashok R., Luscombe, Nicholas M., Saieva, Luciano, Pellizzoni, Livio, Smith, Christopher W.J., Curk, Tomaž, Ule, Jernej
Publicado 2019

The U2AF1(S34F) mutation induces lineage-specific splicing alterations in myelodysplastic syndromes

por Yip, Bon Ham, Steeples, Violetta, Repapi, Emmanouela, Armstrong, Richard N., Llorian, Miriam, Roy, Swagata, Shaw, Jacqueline, Dolatshad, Hamid, Taylor, Stephen, Verma, Amit, Bartenstein, Matthias, Vyas, Paresh, Cross, Nicholas C.P., Malcovati, Luca, Cazzola, Mario, Hellström-Lindberg, Eva, Ogawa, Seishi, Smith, Christopher W.J., Pellagatti, Andrea, Boultwood, Jacqueline
Publicado 2017