Development of Selective Axonopathy in Adult Sensory Neurons Isolated From Diabetic Rats: Role of Glucose-Induced Oxidative Stress

por Zherebitskaya, Elena, Akude, Eli, Smith, Darrell R., Fernyhough, Paul
Publicado 2009

Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

por Akude, Eli, Zherebitskaya, Elena, Chowdhury, Subir K. Roy, Smith, Darrell R., Dobrowsky, Rick T., Fernyhough, Paul
Publicado 2011

Sensory neurons derived from diabetic rats exhibit deficits in functional glycolysis and ATP that are ameliorated by IGF-1

por Aghanoori, Mohamad-Reza, Margulets, Vicky, Smith, Darrell R., Kirshenbaum, Lorrie A., Gitler, Daniel, Fernyhough, Paul
Publicado 2021

Sensory neurons derived from diabetic rats have diminished internal Ca(2+) stores linked to impaired re-uptake by the endoplasmic reticulum

por Zherebitskaya, Elena, Schapansky, Jason, Akude, Eli, Smith, Darrell R, Van der Ploeg, Randy, Solovyova, Natasha, Verkhratsky, Alexei, Fernyhough, Paul
Publicado 2012

Mitochondrial Respiratory Chain Dysfunction in Dorsal Root Ganglia of Streptozotocin-Induced Diabetic Rats and Its Correction by Insulin Treatment

por Chowdhury, Subir K. Roy, Zherebitskaya, Elena, Smith, Darrell R., Akude, Eli, Chattopadhyay, Sharmila, Jolivalt, Corinne G., Calcutt, Nigel A., Fernyhough, Paul
Publicado 2010

Temporal dystrophic remodeling within the intrinsic cardiac nervous system of the streptozotocin-induced diabetic rat model

por Menard, Chantalle E, Durston, Melanie, Zherebitskaya, Elena, Smith, Darrell R, Freed, Darren, Glazner, Gordon W, Tian, Ganghong, Fernyhough, Paul, Arora, Rakesh C
Publicado 2014

Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons

por Saleh, Ali, Roy Chowdhury, Subir K, Smith, Darrell R, Balakrishnan, Savitha, Tessler, Lori, Schartner, Emily, Bilodeau, Andre, Van Der Ploeg, Randy, Fernyhough, Paul
Publicado 2013

Insulin-like growth factor-1 activates AMPK to augment mitochondrial function and correct neuronal metabolism in sensory neurons in type 1 diabetes

por Aghanoori, Mohamad-Reza, Smith, Darrell R., Shariati-Ievari, Shiva, Ajisebutu, Andrew, Nguyen, Annee, Desmond, Fiona, Jesus, Carlos H.A., Zhou, Xiajun, Calcutt, Nigel A., Aliani, Michel, Fernyhough, Paul
Publicado 2018

Muscarinic Toxin 7 Signals Via Ca(2+)/Calmodulin-Dependent Protein Kinase Kinase β to Augment Mitochondrial Function and Prevent Neurodegeneration

por Saleh, Ali, Sabbir, Mohammad Golam, Aghanoori, Mohamad-Reza, Smith, Darrell R., Roy Chowdhury, Subir K., Tessler, Lori, Brown, Jennifer, Gedarevich, Eva, Kassahun, Markos Z., Frizzi, Katie, Calcutt, Nigel A., Fernyhough, Paul
Publicado 2020

CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth

por Aghanoori, Mohamad-Reza, Agarwal, Prasoon, Gauvin, Evan, Nagalingam, Raghu S., Bonomo, Raiza, Yathindranath, Vinith, Smith, Darrell R., Hai, Yan, Lee, Samantha, Jolivalt, Corinne G., Calcutt, Nigel A., Jones, Meaghan J., Czubryt, Michael P., Miller, Donald W., Dolinsky, Vernon W., Mansuy-Aubert, Virginie, Fernyhough, Paul
Publicado 2022