Comparative genomics: From genotype to disease phenotype in the leishmaniases

por Smith, Deborah F., Peacock, Christopher S., Cruz, Angela K.
Publicado 2007

RepSeq – A database of amino acid repeats present in lower eukaryotic pathogens

por Depledge, Daniel P, Lower, Ryan PJ, Smith, Deborah F
Publicado 2007

TbARF1 influences lysosomal function but not endocytosis in procyclic stage Trypanosoma brucei

por Price, Helen P., Stark, Meg, Smith, Barbara, Smith, Deborah F.
Publicado 2007

The small GTPase ARL2 is required for cytokinesis in Trypanosoma brucei

por Price, Helen P., Peltan, Adam, Stark, Meg, Smith, Deborah F.
Publicado 2010

Identification of Drosophila Gene Products Required for Phagocytosis of Leishmania donovani

por Peltan, Adam, Briggs, Laura, Matthews, Gareth, Sweeney, Sean T., Smith, Deborah F.
Publicado 2012

Kinetoplastid PPEF phosphatases: Dual acylated proteins expressed in the endomembrane system of Leishmania

por Mills, Elena, Price, Helen P., Johner, Andrea, Emerson, Jenny E., Smith, Deborah F.
Publicado 2007

Myristoyl-CoA:protein N-myristoyltransferase depletion in trypanosomes causes avirulence and endocytic defects

por Price, Helen P., Güther, M. Lucia S., Ferguson, Michael A.J., Smith, Deborah F.
Publicado 2010

Genetic validation of Leishmania genes essential for amastigote survival in vivo using N-myristoyltransferase as a model

por Paape, Daniel, Prendergast, Catriona T., Price, Helen P., Doehl, Johannes S. P., Smith, Deborah F.
Publicado 2020

Global Profiling and Inhibition of Protein Lipidation in Vector and Host Stages of the Sleeping Sickness Parasite Trypanosoma brucei

por Wright, Megan H., Paape, Daniel, Price, Helen P., Smith, Deborah F., Tate, Edward W.
Publicado 2016

Validation of a new method for immobilising kinetoplastid parasites for live cell imaging

por Price, Helen P., MacLean, Lorna, Marrison, Joanne, O’Toole, Peter J., Smith, Deborah F.
Publicado 2010

The stage-regulated HASPB and SHERP proteins are essential for differentiation of the protozoan parasite Leishmania major in its sand fly vector, Phlebotomus papatasi

por Sádlová, Jovana, Price, Helen P, Smith, Barbara A, Votýpka, Jan, Volf, Petr, Smith, Deborah F
Publicado 2010

Hybridization in Parasites: Consequences for Adaptive Evolution, Pathogenesis, and Public Health in a Changing World

por King, Kayla C., Stelkens, Rike B., Webster, Joanne P., Smith, Deborah F., Brockhurst, Michael A.
Publicado 2015

The Leishmania major BBSome subunit BBS1 is essential for parasite virulence in the mammalian host

por Price, Helen P, Paape, Daniel, Hodgkinson, Michael R, Farrant, Katie, Doehl, Johannes, Stark, Meg, Smith, Deborah F
Publicado 2013

Global Analysis of Protein N-Myristoylation and Exploration of N-Myristoyltransferase as a Drug Target in the Neglected Human Pathogen Leishmania donovani

por Wright, Megan H., Paape, Daniel, Storck, Elisabeth M., Serwa, Remigiusz A., Smith, Deborah F., Tate, Edward W.
Publicado 2015

Dynamic Imaging of Experimental Leishmania donovani-Induced Hepatic Granulomas Detects Kupffer Cell-Restricted Antigen Presentation to Antigen-Specific CD8(+) T Cells

por Beattie, Lynette, Peltan, Adam, Maroof, Asher, Kirby, Alun, Brown, Najmeeyah, Coles, Mark, Smith, Deborah F., Kaye, Paul M.
Publicado 2010

Comparative Expression Profiling of Leishmania: Modulation in Gene Expression between Species and in Different Host Genetic Backgrounds

por Depledge, Daniel P., Evans, Krystal J., Ivens, Alasdair C., Aziz, Naveed, Maroof, Asher, Kaye, Paul M., Smith, Deborah F.
Publicado 2009

Trafficking and release of Leishmania metacyclic HASPB on macrophage invasion

por MacLean, Lorna M, O'Toole, Peter J, Stark, Meg, Marrison, Jo, Seelenmeyer, Claudia, Nickel, Walter, Smith, Deborah F
Publicado 2012

Using a Non-Image-Based Medium-Throughput Assay for Screening Compounds Targeting N-myristoylation in Intracellular Leishmania Amastigotes

por Paape, Daniel, Bell, Andrew S., Heal, William P., Hutton, Jennie A., Leatherbarrow, Robin J., Tate, Edward W., Smith, Deborah F.
Publicado 2014

Leishmania HASP and SHERP Genes Are Required for In Vivo Differentiation, Parasite Transmission and Virulence Attenuation in the Host

por Doehl, Johannes S. P., Sádlová, Jovana, Aslan, Hamide, Pružinová, Kateřina, Metangmo, Sonia, Votýpka, Jan, Kamhawi, Shaden, Volf, Petr, Smith, Deborah F.
Publicado 2017

A role for the vesicle-associated tubulin binding protein ARL6 (BBS3) in flagellum extension in Trypanosoma brucei

por Price, Helen P., Hodgkinson, Michael R., Wright, Megan H., Tate, Edward W., Smith, Barbara A., Carrington, Mark, Stark, Meg, Smith, Deborah F.
Publicado 2012