How neurons maintain their axons long-term: an integrated view of axon biology and pathology

por Smith, Gaynor, Sweeney, Sean T., O’Kane, Cahir J., Prokop, Andreas
Publicado 2023

Autophagic and endo-lysosomal dysfunction in neurodegenerative disease

por Malik, Bilal R., Maddison, Daniel C., Smith, Gaynor A., Peters, Owen M.
Publicado 2019

Influence of chronic L-DOPA treatment on immune response following allogeneic and xenogeneic graft in a rat model of Parkinson’s disease

por Breger, Ludivine S., Kienle, Korbinian, Smith, Gaynor A., Dunnett, Stephen B., Lane, Emma L.
Publicado 2017

Progressive decline of glucocerebrosidase in aging and Parkinson's disease

por Rocha, Emily M, Smith, Gaynor A, Park, Eric, Cao, Hongmei, Brown, Eilish, Hallett, Penelope, Isacson, Ole
Publicado 2015

Dopaminergic Progenitors Derived From Epiblast Stem Cells Function Similarly to Primary VM-Derived Progenitors When Transplanted Into a Parkinson’s Disease Model

por Precious, Sophie V., Smith, Gaynor A., Heuer, Andreas, Jaeger, Ines, Lane, Emma L., Dunnett, Stephen B., Li, Meng, Kelly, Claire M., Rosser, Anne E.
Publicado 2020

TSG101 negatively regulates mitochondrial biogenesis in axons

por Lin, Tzu-Huai, Bis-Brewer, Dana M., Sheehan, Amy E., Townsend, Louise N., Maddison, Daniel C., Züchner, Stephan, Smith, Gaynor A., Freeman, Marc R.
Publicado 2021

Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease

por Davies, Sian E., Hallett, Penelope J., Moens, Thomas, Smith, Gaynor, Mangano, Emily, Kim, Hyoung Tae, Goldberg, Alfred L., Liu, Ji-Long, Isacson, Ole, Tofaris, George K.
Publicado 2014

A Nurr1 Agonist Causes Neuroprotection in a Parkinson’s Disease Lesion Model Primed with the Toll-Like Receptor 3 dsRNA Inflammatory Stimulant Poly(I:C)

por Smith, Gaynor A., Rocha, Emily M., Rooney, Thomas, Barneoud, Pascal, McLean, Jesse R., Beagan, Jonathan, Osborn, Teresia, Coimbra, Madeleine, Luo, Yongyi, Hallett, Penelope J., Isacson, Ole
Publicado 2015

Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson’s Disease

por Rees, Daniel, Beynon, Amy L., Lelos, Mariah J., Smith, Gaynor A., Roberts, Luke D., Phelps, Lyndsey, Dunnett, Stephen B., Morgan, Alwena H., Brown, Rowan M., Wells, Timothy, Davies, Jeffrey S.
Publicado 2022

Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation

por Smith, Gaynor A., Lin, Tzu-Huai, Sheehan, Amy E., Van der Goes van Naters, Wynand, Neukomm, Lukas J., Graves, Hillary K., Bis-Brewer, Dana M., Züchner, Stephan, Freeman, Marc R.
Publicado 2019

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice

por Rocha, Emily M., Smith, Gaynor A., Park, Eric, Cao, Hongmei, Graham, Anne-Renee, Brown, Eilish, McLean, Jesse R., Hayes, Melissa A., Beagan, Jonathan, Izen, Sarah C., Perez-Torres, Eduardo, Hallett, Penelope J., Isacson, Ole
Publicado 2015