Novel dual‐action prodrug triggers apoptosis in glioblastoma cells by releasing a glutathione quencher and lysine‐specific histone demethylase 1A inhibitor

por Engel, Martin, Gee, Yi Sing, Cross, Dale, Maccarone, Alan, Heng, Benjamin, Hulme, Amy, Smith, Grady, Guillemin, Gilles J., Stringer, Brett W., Hyland, Christopher J. T., Ooi, Lezanne
Publicado 2019

A Read/Write Mechanism Connects p300 Bromodomain Function to H2A.Z Acetylation

por Colino-Sanguino, Yolanda, Cornett, Evan M., Moulder, David, Smith, Grady C., Hrit, Joel, Cordeiro-Spinetti, Eric, Vaughan, Robert M., Krajewski, Krzysztof, Rothbart, Scott B., Clark, Susan J., Valdés-Mora, Fátima
Publicado 2019

Differentiation of brain and retinal organoids from confluent cultures of pluripotent stem cells connected by nerve-like axonal projections of optic origin

por Fernando, Milan, Lee, Scott, Wark, Jesse R., Xiao, Di, Lim, Benjamin Y., O’Hara-Wright, Michelle, Kim, Hani J., Smith, Grady C., Wong, Ted, Teber, Erdahl T., Ali, Robin R., Yang, Pengyi, Graham, Mark E., Gonzalez-Cordero, Anai
Publicado 2022

Constitutively bound CTCF sites maintain 3D chromatin architecture and long-range epigenetically regulated domains

por Khoury, Amanda, Achinger-Kawecka, Joanna, Bert, Saul A., Smith, Grady C., French, Hugh J., Luu, Phuc-Loi, Peters, Timothy J., Du, Qian, Parry, Aled J., Valdes-Mora, Fatima, Taberlay, Phillippa C., Stirzaker, Clare, Statham, Aaron L., Clark, Susan J.
Publicado 2020

Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer

por Achinger-Kawecka, Joanna, Valdes-Mora, Fatima, Luu, Phuc-Loi, Giles, Katherine A., Caldon, C. Elizabeth, Qu, Wenjia, Nair, Shalima, Soto, Sebastian, Locke, Warwick J., Yeo-Teh, Nicole S., Gould, Cathryn M., Du, Qian, Smith, Grady C., Ramos, Irene R., Fernandez, Kristine F., Hoon, Dave S., Gee, Julia M. W., Stirzaker, Clare, Clark, Susan J.
Publicado 2020

PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia

por Konttinen, Henna, Cabral-da-Silva, Mauricio e Castro, Ohtonen, Sohvi, Wojciechowski, Sara, Shakirzyanova, Anastasia, Caligola, Simone, Giugno, Rosalba, Ishchenko, Yevheniia, Hernández, Damián, Fazaludeen, Mohammad Feroze, Eamen, Shaila, Budia, Mireia Gómez, Fagerlund, Ilkka, Scoyni, Flavia, Korhonen, Paula, Huber, Nadine, Haapasalo, Annakaisa, Hewitt, Alex W., Vickers, James, Smith, Grady C., Oksanen, Minna, Graff, Caroline, Kanninen, Katja M., Lehtonen, Sarka, Propson, Nicholas, Schwartz, Michael P., Pébay, Alice, Koistinaho, Jari, Ooi, Lezanne, Malm, Tarja
Publicado 2019