The unfolded protein response: mechanisms and therapy of neurodegeneration

por Smith, Heather L., Mallucci, Giovanna R.
Publicado 2016

PINK1 disables the anti-fission machinery to segregate damaged mitochondria for mitophagy

por Pryde, Kenneth R., Smith, Heather L., Chau, Kai-Yin, Schapira, Anthony H.V.
Publicado 2016

A comprehensive approach to zinc-finger recombinase customization enables genomic targeting in human cells

por Gaj, Thomas, Mercer, Andrew C., Sirk, Shannon J., Smith, Heather L., Barbas, Carlos F.
Publicado 2013

Targeting the Unfolded Protein Response as a Disease-Modifying Pathway in Dementia

por Sidhom, Emad, O’Brien, John T., Butcher, Adrian J., Smith, Heather L., Mallucci, Giovanna R., Underwood, Benjamin R.
Publicado 2022

Mitochondrial support of persistent presynaptic vesicle mobilization with age-dependent synaptic growth after LTP

por Smith, Heather L, Bourne, Jennifer N, Cao, Guan, Chirillo, Michael A, Ostroff, Linnaea E, Watson, Deborah J, Harris, Kristen M
Publicado 2016

TrkB signaling regulates the cold-shock protein RBM3-mediated neuroprotection

por Peretti, Diego, Smith, Heather L, Verity, Nicholas, Humoud, Ibrahim, de Weerd, Lis, Swinden, Dean P, Hayes, Joseph, Mallucci, Giovanna R
Publicado 2021

Tonic signaling from O(2) sensors sets neural circuit activity and behavioral state

por Busch, Karl Emanuel, Laurent, Patrick, Soltesz, Zoltan, Murphy, Robin Joseph, Faivre, Olivier, Hedwig, Berthold, Thomas, Martin, Smith, Heather L., de Bono, Mario
Publicado 2012

ASO targeting RBM3 temperature‐controlled poison exon splicing prevents neurodegeneration in vivo

por Preußner, Marco, Smith, Heather L, Hughes, Daniel, Zhang, Min, Emmerichs, Ann‐Kathrin, Scalzitti, Silvia, Peretti, Diego, Swinden, Dean, Neumann, Alexander, Haltenhof, Tom, Mallucci, Giovanna R, Heyd, Florian
Publicado 2023

Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration

por Smith, Heather L., Freeman, Oliver J., Butcher, Adrian J., Holmqvist, Staffan, Humoud, Ibrahim, Schätzl, Tobias, Hughes, Daniel T., Verity, Nicholas C., Swinden, Dean P., Hayes, Joseph, de Weerd, Lis, Rowitch, David H., Franklin, Robin J.M., Mallucci, Giovanna R.
Publicado 2020