Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy

por Tang, Si Jie, Fesharaki-Zadeh, Arman, Takahashi, Hideyuki, Nies, Sarah Helena, Smith, Levi M., Luo, Anin, Chyung, Annabel, Chiasseu, Marius, Strittmatter, Stephen M.
Publicado 2020

Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy

por Brody, A. Harrison, Nies, Sarah Helena, Guan, Fulin, Smith, Levi M., Mukherjee, Bandhan, Salazar, Santiago A., Lee, Suho, Lam, Tu Kiet T., Strittmatter, Stephen M.
Publicado 2022

Correction: Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy

por Brody, A. Harrison, Nies, Sarah Helena, Guan, Fulin, Smith, Levi M., Mukherjee, Bandhan, Salazar, Santiago A., Lee, Suho, Lam, Tu Kiet T., Strittmatter, Stephen M.
Publicado 2022

Anti‐PrP(C) antibody rescues cognition and synapses in transgenic alzheimer mice

por Cox, Timothy O., Gunther, Erik C., Brody, A. Harrison, Chiasseu, Marius T., Stoner, Austin, Smith, Levi M., Haas, Laura T., Hammersley, Jayne, Rees, Gareth, Dosanjh, Bhupinder, Groves, Maria, Gardener, Matthew, Dobson, Claire, Vaughan, Tristan, Chessell, Iain, Billinton, Andrew, Strittmatter, Stephen M.
Publicado 2019

Rescue of Transgenic Alzheimer’s Pathophysiology by Polymeric Cellular Prion Protein Antagonists

por Gunther, Erik C., Smith, Levi M., Kostylev, Mikhail A., Cox, Timothy O., Kaufman, Adam C., Lee, Suho, Folta-Stogniew, Ewa, Maynard, George D., Um, Ji Won, Stagi, Massimiliano, Heiss, Jacqueline K., Stoner, Austin, Noble, Geoff P., Takahashi, Hideyuki, Haas, Laura T., Schneekloth, John S., Merkel, Janie, Teran, Christopher, Naderi, Zahra K., Supattapone, Surachai, Strittmatter, Stephen M.
Publicado 2019

Regulated Induced Proximity Targeting Chimeras (RIPTACs): a Novel Heterobifunctional Small Molecule Therapeutic Strategy for Killing Cancer Cells Selectively

por Raina, Kanak, Forbes, Chris D., Stronk, Rebecca, Rappi, Jonathan P., Eastman, Kyle J., Gerritz, Samuel W., Yu, Xinheng, Li, Hao, Bhardwaj, Amit, Forgione, Mia, Hundt, Abigail, King, Madeline P., Posner, Zoe M., Denny, Allison, McGovern, Andrew, Puleo, David E., Garvin, Ethan, Chenard, Rebekka, Zaware, Nilesh, Mousseau, James J., Macaluso, Jennifer, Martin, Michael, Bassoli, Kyle, Jones, Kelli, Garcia, Marco, Howard, Katia, Smith, Levi M., Chen, Jinshan M., De Leon, Cesar A., Hines, John, Kayser-Bricker, Katherine J., Crews, Craig M.
Publicado 2023