Metabolic Plasticity in Melanoma Progression and Response to Oncogene Targeted Therapies

por Alkaraki, Arwa, McArthur, Grant A., Sheppard, Karen E., Smith, Lorey K.
Publicado 2021

Discovery and analysis of consistent active sub-networks in cancers

por Gaire, Raj K, Smith, Lorey, Humbert, Patrick, Bailey, James, Stuckey, Peter J, Haviv, Izhak
Publicado 2013

Obesity and the Impact on Cutaneous Melanoma: Friend or Foe?

por Smith, Lorey K., Arabi, Shaghayegh, Lelliott, Emily J., McArthur, Grant A., Sheppard, Karen E.
Publicado 2020

The therapeutic potential of targeting minimal residual disease in melanoma

por Patel, Riyaben P, Somasundram, Pretashini M, Smith, Lorey K., Sheppard, Karen E., McArthur, Grant A.
Publicado 2023

CDK4/6 Inhibition Reprograms Mitochondrial Metabolism in BRAF(V600) Melanoma via a p53 Dependent Pathway

por Santiappillai, Nancy T., Abuhammad, Shatha, Slater, Alison, Kirby, Laura, McArthur, Grant A., Sheppard, Karen E., Smith, Lorey K.
Publicado 2021

Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAF(V600) melanoma cells

por Smith, Lorey K., Parmenter, Tiffany, Gould, Cathryn M., Madhamshettiwar, Piyush B., Sheppard, Karen E., Simpson, Kaylene J., McArthur, Grant A.
Publicado 2020

Scribble Modulates the MAPK/Fra1 Pathway to Disrupt Luminal and Ductal Integrity and Suppress Tumour Formation in the Mammary Gland

por Godde, Nathan J., Sheridan, Julie M., Smith, Lorey K., Pearson, Helen B., Britt, Kara L., Galea, Ryan C., Yates, Laura L., Visvader, Jane E., Humbert, Patrick O.
Publicado 2014

Enhancing Adoptive Cell Transfer with Combination BRAF-MEK and CDK4/6 Inhibitors in Melanoma

por Lau, Peter Kar Han, Cullinane, Carleen, Jackson, Susan, Walker, Rachael, Smith, Lorey K., Slater, Alison, Kirby, Laura, Patel, Riyaben P., von Scheidt, Bianca, Slaney, Clare Y., McArthur, Grant A., Sheppard, Karen E.
Publicado 2021

Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia

por So, Joan, Lewis, Alexander C, Smith, Lorey K, Stanley, Kym, Franich, Rheana, Yoannidis, David, Pijpers, Lizzy, Dominguez, Pilar, Hogg, Simon J, Vervoort, Stephin J, Brown, Fiona C, Johnstone, Ricky W, McDonald, Gabrielle, Ulanet, Danielle B, Murtie, Josh, Gruber, Emily, Kats, Lev M
Publicado 2022

Phenotypic Consequences of SLC25A40-ABCB1 Fusions beyond Drug Resistance in High-Grade Serous Ovarian Cancer

por Pishas, Kathleen I., Cowley, Karla J., Pandey, Ahwan, Hoang, Therese, Beach, Jessica A., Luu, Jennii, Vary, Robert, Smith, Lorey K., Shembrey, Carolyn E., Rashoo, Nineveh, White, Madelynne O., Simpson, Kaylene J., Bild, Andrea, Griffiths, Jason I., Cheasley, Dane, Campbell, Ian, Bowtell, David D. L., Christie, Elizabeth L.
Publicado 2021

Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES)

por Lau, Peter Kar Han, Feran, Breon, Smith, Lorey, Lasocki, Arian, Molania, Ramyar, Smith, Kortnye, Weppler, Alison, Angel, Christopher, Kee, Damien, Bhave, Prachi, Lee, Belinda, Young, Richard J, Iravani, Amir, Yeang, Hanxian Aw, Vergara, Ismael A, Kok, David, Drummond, Kate, Neeson, Paul Joseph, Sheppard, Karen E, Papenfuss, Tony, Solomon, Benjamin J, Sandhu, Shahneen, McArthur, Grant A
Publicado 2021

Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF(V600) melanoma

por Smith, Lorey K., Parmenter, Tiffany, Kleinschmidt, Margarete, Kusnadi, Eric P., Kang, Jian, Martin, Claire A., Lau, Peter, Patel, Riyaben, Lorent, Julie, Papadopoli, David, Trigos, Anna, Ward, Teresa, Rao, Aparna D., Lelliott, Emily J., Sheppard, Karen E., Goode, David, Hicks, Rodney J., Tiganis, Tony, Simpson, Kaylene J., Larsson, Ola, Blythe, Benjamin, Cullinane, Carleen, Wickramasinghe, Vihandha O., Pearson, Richard B., McArthur, Grant A.
Publicado 2022

Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma

por AbuHammad, Shatha, Cullinane, Carleen, Martin, Claire, Bacolas, Zoe, Ward, Teresa, Chen, Huiqin, Slater, Alison, Ardley, Kerry, Kirby, Laura, Chan, Keefe T., Brajanovski, Natalie, Smith, Lorey K., Rao, Aparna D., Lelliott, Emily J., Kleinschmidt, Margarete, Vergara, Ismael A., Papenfuss, Anthony T., Lau, Peter, Ghosh, Prerana, Haupt, Sue, Haupt, Ygal, Sanij, Elaine, Poortinga, Gretchen, Pearson, Richard B., Falk, Hendrik, Curtis, David J., Stupple, Paul, Devlin, Mark, Street, Ian, Davies, Michael A., McArthur, Grant A., Sheppard, Karen E.
Publicado 2019

Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death

por Garciaz, Sylvain, Guirguis, Andrew A., Müller, Sebastian, Brown, Fiona C., Chan, Yih-Chih, Motazedian, Ali, Rowe, Caitlin L., Kuzich, James A., Chan, Kah Lok, Tran, Kevin, Smith, Lorey, MacPherson, Laura, Liddicoat, Brian, Lam, Enid Y.N., Cañeque, Tatiana, Burr, Marian L., Litalien, Véronique, Pomilio, Giovanna, Poplineau, Mathilde, Duprez, Estelle, Dawson, Sarah-Jane, Ramm, Georg, Cox, Andrew G., Brown, Kristin K., Huang, David C.S., Wei, Andrew H., McArthur, Kate, Rodriguez, Raphaël, Dawson, Mark A.
Publicado 2022

Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway

por Hannan, Katherine M., Soo, Priscilla, Wong, Mei S., Lee, Justine K., Hein, Nadine, Poh, Perlita, Wysoke, Kira D., Williams, Tobias D., Montellese, Christian, Smith, Lorey K., Al-Obaidi, Sheren J., Núñez-Villacís, Lorena, Pavy, Megan, He, Jin-Shu, Parsons, Kate M., Loring, Karagh E., Morrison, Tess, Diesch, Jeannine, Burgio, Gaetan, Ferreira, Rita, Feng, Zhi-Ping, Gould, Cathryn M., Madhamshettiwar, Piyush B., Flygare, Johan, Gonda, Thomas J., Simpson, Kaylene J., Kutay, Ulrike, Pearson, Richard B., Engel, Christoph, Watkins, Nicholas J., Hannan, Ross D., George, Amee J.
Publicado 2022