Antioxidant properties of MitoTEMPOL and its hydroxylamine

por Trnka, Jan, Blaikie, Frances H., Logan, Angela, Smith, Robin A. J., Murphy, Michael P.
Publicado 2008

P-glycoprotein (Mdr1a/1b) and breast cancer resistance protein (Bcrp) decrease the uptake of hydrophobic alkyl triphenylphosphonium cations by the brain

por Porteous, Carolyn M., Menon, David K., Aigbirhio, Franklin I., Smith, Robin A.J., Murphy, Michael P.
Publicado 2013

Assessing the Delivery of Molecules to the Mitochondrial Matrix Using Click Chemistry

por Hoogewijs, Kurt, James, Andrew M., Smith, Robin A. J., Gait, Michael J., Murphy, Michael P., Lightowlers, Robert N.
Publicado 2016

Synthesis of triphenylphosphonium vitamin E derivatives as mitochondria-targeted antioxidants

por Jameson, Victoria J.A., Cochemé, Helena M., Logan, Angela, Hanton, Lyall R., Smith, Robin A.J., Murphy, Michael P.
Publicado 2015

ClickIn: a flexible protocol for quantifying mitochondrial uptake of nucleobase derivatives

por Hoogewijs, Kurt, James, Andrew M., Smith, Robin A. J., Abendroth, Frank, Gait, Michael J., Murphy, Michael P., Lightowlers, Robert N.
Publicado 2017

Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by r...

por Chouchani, Edward T., Hurd, Thomas R., Nadtochiy, Sergiy M., Brookes, Paul S., Fearnley, Ian M., Lilley, Kathryn S., Smith, Robin A. J., Murphy, Michael P.
Publicado 2010

A mitochondria-targeted derivative of ascorbate: MitoC

por Finichiu, Peter G., Larsen, David S., Evans, Cameron, Larsen, Lesley, Bright, Thomas P., Robb, Ellen L., Trnka, Jan, Prime, Tracy A., James, Andrew M., Smith, Robin A.J., Murphy, Michael P.
Publicado 2015

A Novel Class of Mitochondria-Targeted Soft Electrophiles Modifies Mitochondrial Proteins and Inhibits Mitochondrial Metabolism in Breast Cancer Cells through Redox Mechanisms

por Vayalil, Praveen K., Oh, Joo-Yeun, Zhou, Fen, Diers, Anne R., Smith, M. Ryan, Golzarian, Hafez, Oliver, Patsy G., Smith, Robin A. J., Murphy, Michael P., Velu, Sadanandan E., Landar, Aimee
Publicado 2015

Re-Directing an Alkylating Agent to Mitochondria Alters Drug Target and Cell Death Mechanism

por Mourtada, Rida, Fonseca, Sonali B., Wisnovsky, Simon P., Pereira, Mark P., Wang, Xiaoming, Hurren, Rose, Parfitt, Jeremy, Larsen, Lesley, Smith, Robin A. J., Murphy, Michael P., Schimmer, Aaron D., Kelley, Shana O.
Publicado 2013

Mitochondrial thiol modification by a targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels

por Smith, M. Ryan, Vayalil, Praveen K., Zhou, Fen, Benavides, Gloria A., Beggs, Reena R., Golzarian, Hafez, Nijampatnam, Bhavitavya, Oliver, Patsy G., Smith, Robin A.J., Murphy, Michael P., Velu, Sadanandan E., Landar, Aimee
Publicado 2016

Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry

por Logan, Angela, Pell, Victoria R., Shaffer, Karl J., Evans, Cameron, Stanley, Nathan J., Robb, Ellen L., Prime, Tracy A., Chouchani, Edward T., Cochemé, Helena M., Fearnley, Ian M., Vidoni, Sara, James, Andrew M., Porteous, Carolyn M., Partridge, Linda, Krieg, Thomas, Smith, Robin A.J., Murphy, Michael P.
Publicado 2016

Measurement of H(2)O(2) within Living Drosophila during Aging Using a Ratiometric Mass Spectrometry Probe Targeted to the Mitochondrial Matrix

por Cochemé, Helena M., Quin, Caroline, McQuaker, Stephen J., Cabreiro, Filipe, Logan, Angela, Prime, Tracy A., Abakumova, Irina, Patel, Jigna V., Fearnley, Ian M., James, Andrew M., Porteous, Carolyn M., Smith, Robin A.J., Saeed, Saima, Carré, Jane E., Singer, Mervyn, Gems, David, Hartley, Richard C., Partridge, Linda, Murphy, Michael P.
Publicado 2011

A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes()

por Pun, Pamela Boon Li, Logan, Angela, Darley-Usmar, Victor, Chacko, Balu, Johnson, Michelle S., Huang, Guang W., Rogatti, Sebastian, Prime, Tracy A., Methner, Carmen, Krieg, Thomas, Fearnley, Ian M., Larsen, Lesley, Larsen, David S., Menger, Katja E., Collins, Yvonne, James, Andrew M., Kumar, G.D. Kishore, Hartley, Richard C., Smith, Robin A.J., Murphy, Michael P.
Publicado 2014

Confirmation of the Cardioprotective Effect of MitoGamide in the Diabetic Heart

por Park, Min, Nishimura, Takanori, Baeza-Garza, Carlos D., Caldwell, Stuart T., Pun, Pamela Boon Li, Prag, Hiran A., Young, Tim, Sauchanka, Olga, Logan, Angela, Forkink, Marleen, Gruszczyk, Anja V., Prime, Tracy A., Arndt, Sabine, Naudi, Alba, Pamplona, Reinald, Coughlan, Melinda T., Tate, Mitchel, Ritchie, Rebecca H., Caicci, Federico, Kaludercic, Nina, Di Lisa, Fabio, Smith, Robin A. J., Hartley, Richard C., Murphy, Michael P., Krieg, Thomas
Publicado 2020