Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL

por Upadhyay, Udita, Zhuang, Gerald Z., Diatchenko, Luda, Parisien, Marc, Kang, Yuan, Sarantopoulos, Konstantinos D., Martin, Eden R., Smith, Shad B., Maixner, William, Levitt, Roy C.
Publicado 2019

Association between INADL genetic variant and a subgroup with high risk for TMD in the OPPERA study

por Smith, Shad B, Bair, Eric, Xue, Wei, Slade, Gary D, Dubner, Ronald, Fillingim, Roger B, Greenspan, Joel D, Ohrbach, Richard, Knott, Charlie, Diatchenko, Luda, Maixner, William
Publicado 2014

Impact of human CA8 on thermal antinociception in relation to morphine equivalence in mice

por Fu, Eugene S., Erasso, Diana M., Zhuang, Gerald Z., Upadhyay, Udita, Ozdemir, Mehtap, Wiltshire, Timothy, Sarantopoulos, Konstantinos D., Smith, Shad B., Maixner, William, Martin, Eden R., Levitt, Roy C.
Publicado 2017

Evidence that dry eye represents a chronic overlapping pain condition

por Levitt, Alexandra E, Galor, Anat, Chowdhury, Aneesa R, Felix, Elizabeth R, Sarantopoulos, Constantine D, Zhuang, Gerald Y, Patin, Dennis, Maixner, William, Smith, Shad B, Martin, Eden R, Levitt, Roy C
Publicado 2017

Human Carbonic Anhydrase-8 AAV8 Gene Therapy Inhibits Nerve Growth Factor Signaling Producing Prolonged Analgesia and Anti-Hyperalgesia in Mice

por Zhuang, Gerald Z., Upadhyay, Udita, Tong, Xiaoying, Kang, Yuan, Erasso, Diana M., Fu, Eugene S., Sarantopoulos, Konstantinos D., Martin, Eden R., Wiltshire, Tim, Diatchenko, Luda, Smith, Shad B, Maixner, William, Levitt, Roy C.
Publicado 2018

Carbonic anhydrase-8 gene therapy inhibits the ITPR1-cytosolic free calcium pathway producing analgesia and anti-hyperalgesia

por Levitt, Roy C, Zhuang, Gerald Z, Keeler, Benjamin, Grant, Jeff, Bianchi, Laura, Fu, Eugene S, Zhang, Yan Ping, Erasso, Diana M, Cui, Jian Guo, Wiltshire, Tim, Li, Qiongzhen, Hao, Shuanglin, Sarantopoulos, Konstantinos D, Candiotti, Keith, Smith, Shad B, Maixner, William, Diatchenko, Luda, Martin, Eden R
Publicado 2014

Carbonic Anhydrase-8 Regulates Inflammatory Pain by Inhibiting the ITPR1-Cytosolic Free Calcium Pathway

por Zhuang, Gerald Z., Keeler, Benjamin, Grant, Jeff, Bianchi, Laura, Fu, Eugene S., Zhang, Yan Ping, Erasso, Diana M., Cui, Jian-Guo, Wiltshire, Tim, Li, Qiongzhen, Hao, Shuanglin, Sarantopoulos, Konstantinos D., Candiotti, Keith, Wishnek, Sarah M., Smith, Shad B., Maixner, William, Diatchenko, Luda, Martin, Eden R., Levitt, Roy C.
Publicado 2015

COMT gene locus: new functional variants

por Meloto, Carolina B., Segall, Samantha K., Smith, Shad, Parisien, Marc, Shabalina, Svetlana A., Rizzatti-Barbosa, Célia M., Gauthier, Josée, Tsao, Douglas, Convertino, Marino, Piltonen, Marjo H., Slade, Gary Dmitri, Fillingim, Roger B., Greenspan, Joel D., Ohrbach, Richard, Knott, Charles, Maixner, William, Zaykin, Dmitri, Dokholyan, Nikolay V., Reenilä, Ilkka, Männistö, Pekka T., Diatchenko, Luda
Publicado 2015

Construction of a Global Pain Systems Network Highlights Phospholipid Signaling as a Regulator of Heat Nociception

por Neely, G. Gregory, Rao, Shuan, Costigan, Michael, Mair, Norbert, Racz, Ildiko, Milinkeviciute, Giedre, Meixner, Arabella, Nayanala, Swetha, Griffin, Robert S., Belfer, Inna, Dai, Feng, Smith, Shad, Diatchenko, Luda, Marengo, Stefano, Haubner, Bernhard J., Novatchkova, Maria, Gibson, Dustin, Maixner, William, Pospisilik, J. Andrew, Hirsch, Emilio, Whishaw, Ian Q., Zimmer, Andreas, Gupta, Vaijayanti, Sasaki, Junko, Kanaho, Yasunori, Sasaki, Takehiko, Kress, Michaela, Woolf, Clifford J., Penninger, Josef M.
Publicado 2012

Pain sensitivity and vasopressin analgesia are mediated by a gene-sex-environment interaction

por Mogil, Jeffrey S., Sorge, Robert E., LaCroix-Fralish, Michael L., Smith, Shad B., Fortin, Anny, Sotocinal, Susana G., Ritchie, Jennifer, Austin, Jean-Sebastien, Schorscher-Petcu, Ara, Melmed, Kara, Czerminski, Jan, Bittong, Rosalie A., Mokris, J. Brad, Neubert, John K., Campbell, Claudia M., Edwards, Robert R., Campbell, James N., Crawley, Jacqueline N., Lariviere, William R., Wallace, Margaret R., Sternberg, Wendy F., Balaban, Carey D., Belfer, Inna, Fillingim, Roger B.
Publicado 2011

Genome-wide association reveals contribution of MRAS to painful temporomandibular disorder in males

por Smith, Shad B., Parisien, Marc, Bair, Eric, Belfer, Inna, Chabot-Doré, Anne-Julie, Gris, Pavel, Khoury, Samar, Tansley, Shannon, Torosyan, Yelizaveta, Zaykin, Dmitri V., Bernhardt, Olaf, de Oliveira Serrano, Priscila, Gracely, Richard H., Jain, Deepti, Järvelin, Marjo-Riitta, Kaste, Linda M., Kerr, Kathleen F., Kocher, Thomas, Lähdesmäki, Raija, Laniado, Nadia, Laurie, Cathy C., Laurie, Cecelia A., Männikkö, Minna, Meloto, Carolina B., Nackley, Andrea G., Nelson, Sarah C., Pesonen, Paula, Ribeiro-Dasilva, Margarete C., Rizzatti-Barbosa, Celia M., Sanders, Anne E., Schwahn, Christian, Sipilä, Kirsi, Sofer, Tamar, Teumer, Alexander, Mogil, Jeffrey S., Fillingim, Roger B., Greenspan, Joel D., Ohrbach, Richard, Slade, Gary D., Maixner, William, Diatchenko, Luda
Publicado 2019

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

por Zillikens, M. Carola, Demissie, Serkalem, Hsu, Yi-Hsiang, Yerges-Armstrong, Laura M., Chou, Wen-Chi, Stolk, Lisette, Livshits, Gregory, Broer, Linda, Johnson, Toby, Koller, Daniel L., Kutalik, Zoltán, Luan, Jian’an, Malkin, Ida, Ried, Janina S., Smith, Albert V., Thorleifsson, Gudmar, Vandenput, Liesbeth, Hua Zhao, Jing, Zhang, Weihua, Aghdassi, Ali, Åkesson, Kristina, Amin, Najaf, Baier, Leslie J., Barroso, Inês, Bennett, David A., Bertram, Lars, Biffar, Rainer, Bochud, Murielle, Boehnke, Michael, Borecki, Ingrid B., Buchman, Aron S., Byberg, Liisa, Campbell, Harry, Campos Obanda, Natalia, Cauley, Jane A., Cawthon, Peggy M., Cederberg, Henna, Chen, Zhao, Cho, Nam H., Jin Choi, Hyung, Claussnitzer, Melina, Collins, Francis, Cummings, Steven R., De Jager, Philip L., Demuth, Ilja, Dhonukshe-Rutten, Rosalie A. M., Diatchenko, Luda, Eiriksdottir, Gudny, Enneman, Anke W., Erdos, Mike, Eriksson, Johan G., Eriksson, Joel, Estrada, Karol, Evans, Daniel S., Feitosa, Mary F., Fu, Mao, Garcia, Melissa, Gieger, Christian, Girke, Thomas, Glazer, Nicole L., Grallert, Harald, Grewal, Jagvir, Han, Bok-Ghee, Hanson, Robert L., Hayward, Caroline, Hofman, Albert, Hoffman, Eric P., Homuth, Georg, Hsueh, Wen-Chi, Hubal, Monica J., Hubbard, Alan, Huffman, Kim M., Husted, Lise B., Illig, Thomas, Ingelsson, Erik, Ittermann, Till, Jansson, John-Olov, Jordan, Joanne M., Jula, Antti, Karlsson, Magnus, Khaw, Kay-Tee, Kilpeläinen, Tuomas O., Klopp, Norman, Kloth, Jacqueline S. L., Koistinen, Heikki A., Kraus, William E., Kritchevsky, Stephen, Kuulasmaa, Teemu, Kuusisto, Johanna, Laakso, Markku, Lahti, Jari, Lang, Thomas, Langdahl, Bente L., Launer, Lenore J., Lee, Jong-Young, Lerch, Markus M., Lewis, Joshua R., Lind, Lars, Lindgren, Cecilia, Liu, Yongmei, Liu, Tian, Liu, Youfang, Ljunggren, Östen, Lorentzon, Mattias, Luben, Robert N., Maixner, William, McGuigan, Fiona E., Medina-Gomez, Carolina, Meitinger, Thomas, Melhus, Håkan, Mellström, Dan, Melov, Simon, Michaëlsson, Karl, Mitchell, Braxton D., Morris, Andrew P., Mosekilde, Leif, Newman, Anne, Nielson, Carrie M., O’Connell, Jeffrey R., Oostra, Ben A., Orwoll, Eric S., Palotie, Aarno, Parker, Stephen C. J., Peacock, Munro, Perola, Markus, Peters, Annette, Polasek, Ozren, Prince, Richard L., Räikkönen, Katri, Ralston, Stuart H., Ripatti, Samuli, Robbins, John A., Rotter, Jerome I., Rudan, Igor, Salomaa, Veikko, Satterfield, Suzanne, Schadt, Eric E., Schipf, Sabine, Scott, Laura, Sehmi, Joban, Shen, Jian, Soo Shin, Chan, Sigurdsson, Gunnar, Smith, Shad, Soranzo, Nicole, Stančáková, Alena, Steinhagen-Thiessen, Elisabeth, Streeten, Elizabeth A., Styrkarsdottir, Unnur, Swart, Karin M. A., Tan, Sian-Tsung, Tarnopolsky, Mark A., Thompson, Patricia, Thomson, Cynthia A., Thorsteinsdottir, Unnur, Tikkanen, Emmi, Tranah, Gregory J., Tuomilehto, Jaakko, van Schoor, Natasja M., Verma, Arjun, Vollenweider, Peter, Völzke, Henry, Wactawski-Wende, Jean, Walker, Mark, Weedon, Michael N., Welch, Ryan, Wichmann, H.-Erich, Widen, Elisabeth, Williams, Frances M. K., Wilson, James F., Wright, Nicole C., Xie, Weijia, Yu, Lei, Zhou, Yanhua, Chambers, John C., Döring, Angela, van Duijn, Cornelia M., Econs, Michael J., Gudnason, Vilmundur, Kooner, Jaspal S., Psaty, Bruce M., Spector, Timothy D., Stefansson, Kari, Rivadeneira, Fernando, Uitterlinden, André G., Wareham, Nicholas J., Ossowski, Vicky, Waterworth, Dawn, Loos, Ruth J. F., Karasik, David, Harris, Tamara B., Ohlsson, Claes, Kiel, Douglas P.
Publicado 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

por Zillikens, M. Carola, Demissie, Serkalem, Hsu, Yi-Hsiang, Yerges-Armstrong, Laura M., Chou, Wen-Chi, Stolk, Lisette, Livshits, Gregory, Broer, Linda, Johnson, Toby, Koller, Daniel L., Kutalik, Zoltán, Luan, Jian’an, Malkin, Ida, Ried, Janina S., Smith, Albert V., Thorleifsson, Gudmar, Vandenput, Liesbeth, Hua Zhao, Jing, Zhang, Weihua, Aghdassi, Ali, Åkesson, Kristina, Amin, Najaf, Baier, Leslie J., Barroso, Inês, Bennett, David A., Bertram, Lars, Biffar, Rainer, Bochud, Murielle, Boehnke, Michael, Borecki, Ingrid B., Buchman, Aron S., Byberg, Liisa, Campbell, Harry, Campos Obanda, Natalia, Cauley, Jane A., Cawthon, Peggy M., Cederberg, Henna, Chen, Zhao, Cho, Nam H., Jin Choi, Hyung, Claussnitzer, Melina, Collins, Francis, Cummings, Steven R., De Jager, Philip L., Demuth, Ilja, Dhonukshe-Rutten, Rosalie A. M., Diatchenko, Luda, Eiriksdottir, Gudny, Enneman, Anke W., Erdos, Mike, Eriksson, Johan G., Eriksson, Joel, Estrada, Karol, Evans, Daniel S., Feitosa, Mary F., Fu, Mao, Garcia, Melissa, Gieger, Christian, Girke, Thomas, Glazer, Nicole L., Grallert, Harald, Grewal, Jagvir, Han, Bok-Ghee, Hanson, Robert L., Hayward, Caroline, Hofman, Albert, Hoffman, Eric P., Homuth, Georg, Hsueh, Wen-Chi, Hubal, Monica J., Hubbard, Alan, Huffman, Kim M., Husted, Lise B., Illig, Thomas, Ingelsson, Erik, Ittermann, Till, Jansson, John-Olov, Jordan, Joanne M., Jula, Antti, Karlsson, Magnus, Khaw, Kay-Tee, Kilpeläinen, Tuomas O., Klopp, Norman, Kloth, Jacqueline S. L., Koistinen, Heikki A., Kraus, William E., Kritchevsky, Stephen, Kuulasmaa, Teemu, Kuusisto, Johanna, Laakso, Markku, Lahti, Jari, Lang, Thomas, Langdahl, Bente L., Launer, Lenore J., Lee, Jong-Young, Lerch, Markus M., Lewis, Joshua R., Lind, Lars, Lindgren, Cecilia, Liu, Yongmei, Liu, Tian, Liu, Youfang, Ljunggren, Östen, Lorentzon, Mattias, Luben, Robert N., Maixner, William, McGuigan, Fiona E., Medina-Gomez, Carolina, Meitinger, Thomas, Melhus, Håkan, Mellström, Dan, Melov, Simon, Michaëlsson, Karl, Mitchell, Braxton D., Morris, Andrew P., Mosekilde, Leif, Newman, Anne, Nielson, Carrie M., O’Connell, Jeffrey R., Oostra, Ben A., Orwoll, Eric S., Palotie, Aarno, Parker, Stephen C. J., Peacock, Munro, Perola, Markus, Peters, Annette, Polasek, Ozren, Prince, Richard L., Räikkönen, Katri, Ralston, Stuart H., Ripatti, Samuli, Robbins, John A., Rotter, Jerome I., Rudan, Igor, Salomaa, Veikko, Satterfield, Suzanne, Schadt, Eric E., Schipf, Sabine, Scott, Laura, Sehmi, Joban, Shen, Jian, Soo Shin, Chan, Sigurdsson, Gunnar, Smith, Shad, Soranzo, Nicole, Stančáková, Alena, Steinhagen-Thiessen, Elisabeth, Streeten, Elizabeth A., Styrkarsdottir, Unnur, Swart, Karin M. A., Tan, Sian-Tsung, Tarnopolsky, Mark A., Thompson, Patricia, Thomson, Cynthia A., Thorsteinsdottir, Unnur, Tikkanen, Emmi, Tranah, Gregory J., Tuomilehto, Jaakko, van Schoor, Natasja M., Verma, Arjun, Vollenweider, Peter, Völzke, Henry, Wactawski-Wende, Jean, Walker, Mark, Weedon, Michael N., Welch, Ryan, Wichmann, H.-Erich, Widen, Elisabeth, Williams, Frances M. K., Wilson, James F., Wright, Nicole C., Xie, Weijia, Yu, Lei, Zhou, Yanhua, Chambers, John C., Döring, Angela, van Duijn, Cornelia M., Econs, Michael J., Gudnason, Vilmundur, Kooner, Jaspal S., Psaty, Bruce M., Spector, Timothy D., Stefansson, Kari, Rivadeneira, Fernando, Uitterlinden, André G., Wareham, Nicholas J., Ossowski, Vicky, Waterworth, Dawn, Loos, Ruth J. F., Karasik, David, Harris, Tamara B., Ohlsson, Claes, Kiel, Douglas P.
Publicado 2017

A Meta-Analysis Identifies New Loci Associated with Body Mass index in Individuals of African Ancestry

por Monda, Keri L., Chen, Gary K., Taylor, Kira C., Palmer, Cameron, Edwards, Todd L., Lange, Leslie A., Ng, Maggie C.Y., Adeyemo, Adebowale A., Allison, Matthew A., Bielak, Lawrence F., Chen, Guanji, Graff, Mariaelisa, Irvin, Marguerite R., Rhie, Suhn K., Li, Guo, Liu, Yongmei, Liu, Youfang, Lu, Yingchang, Nalls, Michael A., Sun, Yan V., Wojczynski, Mary K., Yanek, Lisa R., Aldrich, Melinda C., Ademola, Adeyinka, Amos, Christopher I., Bandera, Elisa V., Bock, Cathryn H., Britton, Angela, Broeckel, Ulrich, Cai, Quiyin, Caporaso, Neil E., Carlson, Chris, Carpten, John, Casey, Graham, Chen, Wei-Min, Chen, Fang, Chen, Yii-Der I., Chiang, Charleston W.K., Coetzee, Gerhard A., Demerath, Ellen, Deming-Halverson, Sandra L., Driver, Ryan W., Dubbert, Patricia, Feitosa, Mary F., Freedman, Barry I., Gillanders, Elizabeth M., Gottesman, Omri, Guo, Xiuqing, Haritunians, Talin, Harris, Tamara, Harris, Curtis C., Hennis, Anselm JM, Hernandez, Dena G., McNeill, Lorna H., Howard, Timothy D., Howard, Barbara V., Howard, Virginia J., Johnson, Karen C., Kang, Sun J., Keating, Brendan J., Kolb, Suzanne, Kuller, Lewis H., Kutlar, Abdullah, Langefeld, Carl D., Lettre, Guillaume, Lohman, Kurt, Lotay, Vaneet, Lyon, Helen, Manson, JoAnn E., Maixner, William, Meng, Yan A., Monroe, Kristine R., Morhason-Bello, Imran, Murphy, Adam B., Mychaleckyj, Josyf C., Nadukuru, Rajiv, Nathanson, Katherine L., Nayak, Uma, N’Diaye, Amidou, Nemesure, Barbara, Wu, Suh-Yuh, Leske, M. Cristina, Neslund-Dudas, Christine, Neuhouser, Marian, Nyante, Sarah, Ochs-Balcom, Heather, Ogunniyi, Adesola, Ogundiran, Temidayo O., Ojengbede, Oladosu, Olopade, Olufunmilayo I., Palmer, Julie R., Ruiz-Narvaez, Edward A., Palmer, Nicholette D., Press, Michael F., Rampersaud, Evandine, Rasmussen-Torvik, Laura J., Rodriguez-Gil, Jorge L., Salako, Babatunde, Schadt, Eric E., Schwartz, Ann G., Shriner, Daniel A., Siscovick, David, Smith, Shad B., Wassertheil-Smoller, Sylvia, Speliotes, Elizabeth K., Spitz, Margaret R., Sucheston, Lara, Taylor, Herman, Tayo, Bamidele O., Tucker, Margaret A., Van Den Berg, David J., Velez Edwards, Digna R., Wang, Zhaoming, Wiencke, John K., Winkler, Thomas W., Witte, John S., Wrensch, Margaret, Wu, Xifeng, Yang, James J., Levin, Albert M., Young, Taylor R., Zakai, Neil A., Cushman, Mary, Zanetti, Krista A., Zhao, Jing Hua, Zhao, Wei, Zheng, Yonglan, Zhou, Jie, Ziegler, Regina G., Zmuda, Joseph M., Fernandes, Jyotika K., Gilkeson, Gary S., Kamen, Diane L., Hunt, Kelly J., Spruill, Ida J., Ambrosone, Christine B., Ambs, Stefan, Arnett, Donna K., Atwood, Larry, Becker, Diane M., Berndt, Sonja I., Bernstein, Leslie, Blot, William J., Borecki, Ingrid B., Bottinger, Erwin P., Bowden, Donald W., Burke, Gregory, Chanock, Stephen J., Cooper, Richard S., Ding, Jingzhong, Duggan, David, Evans, Michele K., Fox, Caroline, Garvey, W. Timothy, Bradfield, Jonathan P., Hakonarson, Hakon, Grant, Struan F.A., Hsing, Ann, Chu, Lisa, Hu, Jennifer J., Huo, Dezheng, Ingles, Sue A., John, Esther M., Jordan, Joanne M., Kabagambe, Edmond K., Kardia, Sharon L.R., Kittles, Rick A., Goodman, Phyllis J., Klein, Eric A., Kolonel, Laurence N., Le Marchand, Loic, Liu, Simin, McKnight, Barbara, Millikan, Robert C., Mosley, Thomas H., Padhukasahasram, Badri, Williams, L. Keoki, Patel, Sanjay R., Peters, Ulrike, Pettaway, Curtis A., Peyser, Patricia A., Psaty, Bruce M., Redline, Susan, Rotimi, Charles N., Rybicki, Benjamin A., Sale, Michèle M., Schreiner, Pamela J., Signorello, Lisa B., Singleton, Andrew B., Stanford, Janet L., Strom, Sara S., Thun, Michael J., Vitolins, Mara, Zheng, Wei, Moore, Jason H., Williams, Scott M., Zhu, Xiaofeng, Zonderman, Alan B., Kooperberg, Charles, Papanicolaou, George, Henderson, Brian E., Reiner, Alex P., Hirschhorn, Joel N., Loos, Ruth JF, North, Kari E., Haiman, Christopher A.
Publicado 2013