NMR spectroscopy of basic/aromatic amino acid clusters in membrane proteins

por Zhang, Wenyi, Sato, Takeshi, Smith, Steven O.
Publicado 2006

Anti-Parallel β-Hairpin Structure in Soluble Aβ Oligomers of Aβ40-Dutch and Aβ40-Iowa

por Fu, Ziao, Van Nostrand, William E., Smith, Steven O.
Publicado 2021

An Electrostatic Engine Model for Autoinhibition and Activation of the Epidermal Growth Factor Receptor (EGFR/ErbB) Family

por McLaughlin, Stuart, Smith, Steven O., Hayman, Michael J., Murray, Diana
Publicado 2005

A Highly Redundant Gene Network Controls Assembly of the Outer Spore Wall in S. cerevisiae

por Lin, Coney Pei-Chen, Kim, Carey, Smith, Steven O., Neiman, Aaron M.
Publicado 2013

Coupling of Transmembrane Helix Orientation To Membrane Release of the Juxtamembrane Region in FGFR3

por Tamagaki, Hiroko, Furukawa, Yusuke, Yamaguchi, Ritsuko, Hojo, Hironobu, Aimoto, Saburo, Smith, Steven O., Sato, Takeshi
Publicado 2014

Capping of Aβ42 Oligomers by Small Molecule Inhibitors

por Fu, Ziao, Aucoin, Darryl, Ahmed, Mahiuddin, Ziliox, Martine, Van Nostrand, William E., Smith, Steven O.
Publicado 2014

Impact of Aβ40 and Aβ42 Fibrils on the Transcriptome of Primary Astrocytes and Microglia

por Zhu, Xiaoyue, Schrader, Joseph M., Irizarry, Brandon A., Smith, Steven O., Van Nostrand, William E.
Publicado 2022

Insights into Cerebral Amyloid Angiopathy Type 1 and Type 2 from Comparisons of the Fibrillar Assembly and Stability of the Aβ40-Iowa and Aβ40-Dutch Peptides

por Rajpoot, Jitika, Crooks, Elliot J., Irizarry, Brandon A., Amundson, Ashley, Van Nostrand, William E., Smith, Steven O.
Publicado 2022

Glycines from the APP GXXXG/GXXXA Transmembrane Motifs Promote Formation of Pathogenic Aβ Oligomers in Cells

por Decock, Marie, Stanga, Serena, Octave, Jean-Noël, Dewachter, Ilse, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
Publicado 2016

Cerebral vascular amyloid seeds drive amyloid β-protein fibril assembly with a distinct anti-parallel structure

por Xu, Feng, Fu, Ziao, Dass, Sharmila, Kotarba, AnnMarie E., Davis, Judianne, Smith, Steven O., Van Nostrand, William E.
Publicado 2016

High-Level Expression, Purification and Characterization of a Constitutively Active Thromboxane A2 Receptor Polymorphic Variant

por Xu, Bing, Chakraborty, Raja, Eilers, Markus, Dakshinamurti, Shyamala, O’Neil, Joe D., Smith, Steven O., Bhullar, Rajinder P., Chelikani, Prashen
Publicado 2013

Analysis by a highly sensitive split luciferase assay of the regions involved in APP dimerization and its impact on processing

por Decock, Marie, El Haylani, Laetitia, Stanga, Serena, Dewachter, Ilse, Octave, Jean-Noël, Smith, Steven O., Constantinescu, Stefan N., Kienlen-Campard, Pascal
Publicado 2015

Free backbone carbonyls mediate rhodopsin activation

por Kimata, Naoki, Pope, Andreyah, Sanchez-Reyes, Omar B., Eilers, Markus, Opefi, Chikwado A., Ziliox, Martine, Reeves, Philip J., Smith, Steven O.
Publicado 2016

Structural conversion of neurotoxic amyloid-β(1–42) oligomers to fibrils

por Ahmed, Mahiuddin, Davis, Judianne, Aucoin, Darryl, Sato, Takeshi, Ahuja, Shivani, Aimoto, Saburo, Elliott, James I., Van Nostrand, William E., Smith, Steven O.
Publicado 2010

Human cerebral vascular amyloid contains both antiparallel and parallel in-register Aβ40 fibrils

por Irizarry, Brandon A., Davis, Judianne, Zhu, Xiaoyue, Boon, Baayla D.C., Rozemuller, Annemieke J.M., Van Nostrand, William E., Smith, Steven O.
Publicado 2021

Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization

por Perrin, Florian, Papadopoulos, Nicolas, Suelves, Nuria, Opsomer, Rémi, Vadukul, Devkee M., Vrancx, Céline, Smith, Steven O., Vertommen, Didier, Kienlen-Campard, Pascal, Constantinescu, Stefan N.
Publicado 2020

Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization

por Perrin, Florian, Papadopoulos, Nicolas, Suelves, Nuria, Opsomer, Rémi, Vadukul, Devkee M., Vrancx, Céline, Smith, Steven O., Vertommen, Didier, Kienlen-Campard, Pascal, Constantinescu, Stefan N.
Publicado 2021

Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation

por Kimata, Naoki, Pope, Andreyah, Eilers, Markus, Opefi, Chikwado A., Ziliox, Martine, Hirshfeld, Amiram, Zaitseva, Ekaterina, Vogel, Reiner, Sheves, Mordechai, Reeves, Philip J., Smith, Steven O.
Publicado 2016

β-Sheet Structure within the Extracellular Domain of C99 Regulates Amyloidogenic Processing

por Hu, Yi, Kienlen-Campard, Pascal, Tang, Tzu-Chun, Perrin, Florian, Opsomer, Rémi, Decock, Marie, Pan, Xiaoshu, Octave, Jean-Noel, Constantinescu, Stefan N., Smith, Steven O.
Publicado 2017

Constitutive activation and oncogenicity are mediated by loss of helical structure at the cytosolic boundary of thrombopoietin receptor mutant dimers

por Defour, Jean-Philippe, Leroy, Emilie, Dass, Sharmila, Balligand, Thomas, Levy, Gabriel, Brett, Ian C, Papadopoulos, Nicolas, Mouton, Céline, Genet, Lidvine, Pecquet, Christian, Staerk, Judith, Smith, Steven O, Constantinescu, Stefan N
Publicado 2023