Alternative pathway activation in pregnancy, a measured amount “complements” a successful pregnancy, too much results in adverse events

por Smith‐Jackson, Kate, Harrison, Richard Alexander
Publicado 2022

Assessing the Impact of Prophylactic Eculizumab on Renal Graft Survival in Atypical Hemolytic Uremic Syndrome

por Glover, Emily K., Smith-Jackson, Kate, Brocklebank, Vicky, Wilson, Valerie, Walsh, Patrick R., Montgomery, Emma K., Wong, Edwin K.S., Johnson, Sally, Malina, Michal, Kavanagh, David, Sheerin, Neil S.
Publicado 2023

Plasminogen activator-coated nanobubbles targeting cell-bound β2-glycoprotein I as a novel thrombus-specific thrombolytic strategy

por Macor, Paolo, Durigutto, Paolo, Argenziano, Monica, Smith-Jackson, Kate, Capolla, Sara, Di Leonardo, Valeria, Marchbank, Kevin, Tolva, Valerio Stefano, Semeraro, Fabrizio, Ammollo, Concetta T., Colucci, Mario, Cavalli, Roberta, Meroni, Pierluigi, Tedesco, Francesco
Publicado 2022

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice

por Smith-Jackson, Kate, Yang, Yi, Denton, Harriet, Pappworth, Isabel Y., Cooke, Katie, Barlow, Paul N., Atkinson, John P., Liszewski, M. Kathryn, Pickering, Matthew C., Kavanagh, David, Cook, H. Terence, Marchbank, Kevin J.
Publicado 2019

Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study

por Brocklebank, Vicky, Walsh, Patrick R., Smith-Jackson, Kate, Hallam, Thomas M., Marchbank, Kevin J., Wilson, Valerie, Bigirumurame, Theophile, Dutt, Tina, Montgomery, Emma K., Malina, Michal, Wong, Edwin K. S., Johnson, Sally, Sheerin, Neil S., Kavanagh, David
Publicado 2023

Functional Characterization of Rare Genetic Variants in the N-Terminus of Complement Factor H in aHUS, C3G, and AMD

por Wong, Edwin K. S., Hallam, Thomas M., Brocklebank, Vicky, Walsh, Patrick R., Smith-Jackson, Kate, Shuttleworth, Victoria G., Cox, Thomas E., Anderson, Holly E., Barlow, Paul Nigel, Marchbank, Kevin James, Harris, Claire L., Kavanagh, David
Publicado 2021

A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration

por Hallam, Thomas M., Cox, Thomas E., Smith-Jackson, Kate, Brocklebank, Vicky, Baral, April J., Tzoumas, Nikolaos, Steel, David H., Wong, Edwin K. S., Shuttleworth, Victoria G., Lotery, Andrew J., Harris, Claire L., Marchbank, Kevin J., Kavanagh, David
Publicado 2022

Homodimeric Minimal Factor H: In Vivo Tracking and Extended Dosing Studies in Factor H Deficient Mice

por Kamala, Ola, Malik, Talat H., Hallam, Thomas M., Cox, Thomas E., Yang, Yi, Vyas, Falguni, Luli, Saimir, Connelly, Chloe, Gibson, Beth, Smith-Jackson, Kate, Denton, Harriet, Pappworth, Isabel Y., Huang, Lei, Kavanagh, David, Pickering, Matthew C., Marchbank, Kevin J.
Publicado 2021

Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy

por Brocklebank, Vicky, Kumar, Gurinder, Howie, Alexander J., Chandar, Jayanthi, Milford, David V., Craze, Janet, Evans, Jonathan, Finlay, Eric, Freundlich, Michael, Gale, Daniel P., Inward, Carol, Mraz, Martin, Jones, Caroline, Wong, William, Marks, Stephen D., Connolly, John, Corner, Bronte M., Smith-Jackson, Kate, Walsh, Patrick R., Marchbank, Kevin J., Harris, Claire L., Wilson, Valerie, Wong, Edwin K.S., Malina, Michal, Johnson, Sally, Sheerin, Neil S., Kavanagh, David
Publicado 2020