Astrocytes Sustain Circadian Oscillation and Bidirectionally Determine Circadian Period, But Do Not Regulate Circadian Phase in the Suprachiasmatic Nucleus

por Patton, Andrew P., Smyllie, Nicola J., Chesham, Johanna E., Hastings, Michael H.
Publicado 2022

Temporally chimeric mice reveal flexibility of circadian period-setting in the suprachiasmatic nucleus

por Smyllie, Nicola J., Chesham, Johanna E., Hamnett, Ryan, Maywood, Elizabeth S., Hastings, Michael H.
Publicado 2016

The VIP-VPAC2 neuropeptidergic axis is a cellular pacemaking hub of the suprachiasmatic nucleus circadian circuit

por Patton, Andrew P., Edwards, Mathew D., Smyllie, Nicola J., Hamnett, Ryan, Chesham, Johanna E., Brancaccio, Marco, Maywood, Elizabeth S., Hastings, Michael H.
Publicado 2020

Cryptochrome 1 as a state variable of the circadian clockwork of the suprachiasmatic nucleus: Evidence from translational switching

por McManus, David, Polidarova, Lenka, Smyllie, Nicola J., Patton, Andrew P., Chesham, Johanna E., Maywood, Elizabeth S., Chin, Jason W., Hastings, Michael H.
Publicado 2022

Cryptochrome proteins regulate the circadian intracellular behavior and localization of PER2 in mouse suprachiasmatic nucleus neurons

por Smyllie, Nicola J., Bagnall, James, Koch, Alex A., Niranjan, Dhevahi, Polidarova, Lenka, Chesham, Johanna E., Chin, Jason W., Partch, Carrie L., Loudon, Andrew S. I., Hastings, Michael H.
Publicado 2022

Quantification of protein abundance and interaction defines a mechanism for operation of the circadian clock

por Koch, Alex A, Bagnall, James S, Smyllie, Nicola J, Begley, Nicola, Adamson, Antony D, Fribourgh, Jennifer L, Spiller, David G, Meng, Qing-Jun, Partch, Carrie L, Strimmer, Korbinian, House, Thomas A, Hastings, Michael H, Loudon, Andrew SI
Publicado 2022

Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2

por Smyllie, Nicola J., Pilorz, Violetta, Boyd, James, Meng, Qing-Jun, Saer, Ben, Chesham, Johanna E., Maywood, Elizabeth S., Krogager, Toke P., Spiller, David G., Boot-Handford, Raymond, White, Michael R.H., Hastings, Michael H., Loudon, Andrew S.I.
Publicado 2016

Quantitative live imaging of Venus::BMAL1 in a mouse model reveals complex dynamics of the master circadian clock regulator

por Yang, Nan, Smyllie, Nicola J., Morris, Honor, Gonçalves, Cátia F., Dudek, Michal, Pathiranage, Dharshika R. J., Chesham, Johanna E., Adamson, Antony, Spiller, David G., Zindy, Egor, Bagnall, James, Humphreys, Neil, Hoyland, Judith, Loudon, Andrew S. I., Hastings, Michael H., Meng, Qing-Jun
Publicado 2020

Differential roles for cryptochromes in the mammalian retinal clock

por Wong, Jovi C. Y., Smyllie, Nicola J., Banks, Gareth T., Pothecary, Carina A., Barnard, Alun R., Maywood, Elizabeth S., Jagannath, Aarti, Hughes, Steven, van der Horst, Gijsbertus T. J., MacLaren, Robert E., Hankins, Mark W., Hastings, Michael H., Nolan, Patrick M., Foster, Russell G., Peirson, Stuart N.
Publicado 2018

The Regulatory Factor ZFHX3 Modifies Circadian Function in SCN via an AT Motif-Driven Axis

por Parsons, Michael J., Brancaccio, Marco, Sethi, Siddharth, Maywood, Elizabeth S., Satija, Rahul, Edwards, Jessica K., Jagannath, Aarti, Couch, Yvonne, Finelli, Mattéa J., Smyllie, Nicola J., Esapa, Christopher, Butler, Rachel, Barnard, Alun R., Chesham, Johanna E., Saito, Shoko, Joynson, Greg, Wells, Sara, Foster, Russell G., Oliver, Peter L., Simon, Michelle M., Mallon, Ann-Marie, Hastings, Michael H., Nolan, Patrick M.
Publicado 2015