Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13

por Plagnol, Vincent, Smyth, Deborah J., Todd, John A., Clayton, David G.
Publicado 2009

Genetic Analysis of Adult-Onset Autoimmune Diabetes

por Howson, Joanna M.M., Rosinger, Silke, Smyth, Deborah J., Boehm, Bernhard O., Todd, John A.
Publicado 2011

The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes

por Wallace, Chris, Smyth, Deborah J, Maisuria-Armer, Meeta, Walker, Neil M, Todd, John A, Clayton, David G
Publicado 2009

Evidence That HLA Class I and II Associations With Type 1 Diabetes, Autoantibodies to GAD and Autoantibodies to IA-2, Are Distinct

por Howson, Joanna M.M., Stevens, Helen, Smyth, Deborah J., Walker, Neil M., Chandler, Kyla A., Bingley, Polly J., Todd, John A.
Publicado 2011

Reduced Expression of IFIH1 Is Protective for Type 1 Diabetes

por Downes, Kate, Pekalski, Marcin, Angus, Karen L., Hardy, Matthew, Nutland, Sarah, Smyth, Deborah J., Walker, Neil M., Wallace, Chris, Todd, John A.
Publicado 2010

FUT2 Nonsecretor Status Links Type 1 Diabetes Susceptibility and Resistance to Infection

por Smyth, Deborah J., Cooper, Jason D., Howson, Joanna M.M., Clarke, Pamela, Downes, Kate, Mistry, Trupti, Stevens, Helen, Walker, Neil M., Todd, John A.
Publicado 2011

Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes

por Saleh, Nada M, Raj, Srilakshmi M, Smyth, Deborah J, Wallace, Chris, Howson, Joanna M M, Bell, Louise, Walker, Neil M, Stevens, Helen E, Todd, John A
Publicado 2011

The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes

por Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Payne, Felicity, Downes, Kate, Godfrey, Lisa M, Masters, Jennifer, Zeitels, Lauren R, Vella, Adrian, Walker, Neil M, Todd, John A
Publicado 2007

An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects Against Type 1 Diabetes

por Swafford, Austin D.-E., Howson, Joanna M.M., Davison, Lucy J., Wallace, Chris, Smyth, Deborah J., Schuilenburg, Helen, Maisuria-Armer, Meeta, Mistry, Trupti, Lenardo, Michael J., Todd, John A.
Publicado 2011

A Method for Gene-Based Pathway Analysis Using Genomewide Association Study Summary Statistics Reveals Nine New Type 1 Diabetes Associations

por Evangelou, Marina, Smyth, Deborah J, Fortune, Mary D, Burren, Oliver S, Walker, Neil M, Guo, Hui, Onengut-Gumuscu, Suna, Chen, Wei-Min, Concannon, Patrick, Rich, Stephen S, Todd, John A, Wallace, Chris
Publicado 2014

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing

por Rainbow, Daniel B., Yang, Xin, Burren, Oliver, Pekalski, Marcin L., Smyth, Deborah J., Klarqvist, Marcus D. R., Penkett, Christopher J., Brugger, Kim, Martin, Howard, Todd, John A., Wallace, Chris, Wicker, Linda S.
Publicado 2015

Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases

por Plagnol, Vincent, Howson, Joanna M. M., Smyth, Deborah J., Walker, Neil, Hafler, Jason P., Wallace, Chris, Stevens, Helen, Jackson, Laura, Simmonds, Matthew J., Bingley, Polly J., Gough, Stephen C., Todd, John A.
Publicado 2011

Investigating the utility of combining Φ29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray™ genotyping

por Pask, Rebecca, Rance, Helen E, Barratt, Bryan J, Nutland, Sarah, Smyth, Deborah J, Sebastian, Meera, Twells, Rebecca CJ, Smith, Anne, Lam, Alex C, Smink, Luc J, Walker, Neil M, Todd, John A
Publicado 2004

Chromatin activity at GWAS loci identifies T cell states driving complex immune diseases

por Soskic, Blagoje, Cano-Gamez, Eddie, Smyth, Deborah J., Rowan, Wendy C., Nakic, Nikolina, Esparza-Gordillo, Jorge, Bossini-Castillo, Lara, Tough, David F., Larminie, Christopher GC, Bronson, Paola G., Willé, David, Trynka, Gosia
Publicado 2019

Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes

por Taniguchi, Hidenori, Lowe, Christopher E, Cooper, Jason D, Smyth, Deborah J, Bailey, Rebecca, Nutland, Sarah, Healy, Barry C, Lam, Alex C, Burren, Oliver, Walker, Neil M, Smink, Luc J, Wicker, Linda S, Todd, John A
Publicado 2006

The PTPN22 Locus and Rheumatoid Arthritis: No Evidence for an Effect on Risk Independent of Arg620Trp

por Wan Taib, Wan R., Smyth, Deborah J., Merriman, Marilyn E., Dalbeth, Nicola, Gow, Peter J., Harrison, Andrew A., Highton, John, Jones, Peter B. B., Stamp, Lisa, Steer, Sophia, Todd, John A., Merriman, Tony R.
Publicado 2010

Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes

por Wallace, Chris, Rotival, Maxime, Cooper, Jason D., Rice, Catherine M., Yang, Jennie H.M., McNeill, Mhairi, Smyth, Deborah J., Niblett, David, Cambien, François, Tiret, Laurence, Todd, John A., Clayton, David G., Blankenberg, Stefan
Publicado 2012

A Human Type 1 Diabetes Susceptibility Locus Maps to Chromosome 21q22.3

por Concannon, Patrick, Onengut-Gumuscu, Suna, Todd, John A., Smyth, Deborah J., Pociot, Flemming, Bergholdt, Regine, Akolkar, Beena, Erlich, Henry A., Hilner, Joan E., Julier, Cécile, Morahan, Grant, Nerup, Jørn, Nierras, Concepcion R., Chen, Wei-Min, Rich, Stephen S.
Publicado 2008

IL-21 production by CD4(+) effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients

por Ferreira, Ricardo C., Simons, Henry Z., Thompson, Whitney S., Cutler, Antony J., Dopico, Xaquin Castro, Smyth, Deborah J., Mashar, Meghavi, Schuilenburg, Helen, Walker, Neil M., Dunger, David B., Wallace, Chris, Todd, John A., Wicker, Linda S., Pekalski, Marcin L.
Publicado 2015

Inherited Variation in Vitamin D Genes Is Associated With Predisposition to Autoimmune Disease Type 1 Diabetes

por Cooper, Jason D., Smyth, Deborah J., Walker, Neil M., Stevens, Helen, Burren, Oliver S., Wallace, Chris, Greissl, Christopher, Ramos-Lopez, Elizabeth, Hyppönen, Elina, Dunger, David B., Spector, Timothy D., Ouwehand, Willem H., Wang, Thomas J., Badenhoop, Klaus, Todd, John A.
Publicado 2011