Being Flexible: The Voltage-Controllable Activation Gate of Kv Channels

por Labro, Alain J., Snyders, Dirk J.
Publicado 2012

Independent movement of the voltage sensors in K(V)2.1/K(V)6.4 heterotetramers

por Bocksteins, Elke, Snyders, Dirk J., Holmgren, Miguel
Publicado 2017

Coupling of Voltage Sensing to Channel Opening Reflects Intrasubunit Interactions in Kv Channels

por Labro, Alain J., Raes, Adam L., Snyders, Dirk J.
Publicado 2005

The Electrically Silent Kv6.4 Subunit Confers Hyperpolarized Gating Charge Movement in Kv2.1/Kv6.4 Heterotetrameric Channels

por Bocksteins, Elke, Labro, Alain J., Snyders, Dirk J., Mohapatra, Durga P.
Publicado 2012

Modulation of Closed−State Inactivation in Kv2.1/Kv6.4 Heterotetramers as Mechanism for 4−AP Induced Potentiation

por Stas, Jeroen I., Bocksteins, Elke, Labro, Alain J., Snyders, Dirk J.
Publicado 2015

Alkanols inhibit voltage-gated K(+) channels via a distinct gating modifying mechanism that prevents gate opening

por Martínez-Morales, Evelyn, Kopljar, Ivan, Snyders, Dirk J., Labro, Alain J.
Publicado 2015

The anticonvulsant retigabine suppresses neuronal K(V)2-mediated currents

por Stas, Jeroen I., Bocksteins, Elke, Jensen, Camilla S., Schmitt, Nicole, Snyders, Dirk J.
Publicado 2016

K(v)3.1 uses a timely resurgent K(+) current to secure action potential repolarization

por Labro, Alain J., Priest, Michael F., Lacroix, Jérôme J., Snyders, Dirk J., Bezanilla, Francisco
Publicado 2015

Molecular mechanism for depolarization-induced modulation of Kv channel closure

por Labro, Alain J., Lacroix, Jerome J., Villalba-Galea, Carlos A., Snyders, Dirk J., Bezanilla, Francisco
Publicado 2012

The Subfamily-Specific Interaction between Kv2.1 and Kv6.4 Subunits Is Determined by Interactions between the N- and C-termini

por Bocksteins, Elke, Mayeur, Evy, Van Tilborg, Abbi, Regnier, Glenn, Timmermans, Jean-Pierre, Snyders, Dirk J.
Publicado 2014

The contribution of Kv2.2‐mediated currents decreases during the postnatal development of mouse dorsal root ganglion neurons

por Regnier, Glenn, Bocksteins, Elke, Van de Vijver, Gerda, Snyders, Dirk J., van Bogaert, Pierre‐Paul
Publicado 2016

Hydrophobic Drug/Toxin Binding Sites in Voltage-Dependent K(+) and Na(+) Channels

por Van Theemsche, Kenny M., Van de Sande, Dieter V., Snyders, Dirk J., Labro, Alain J.
Publicado 2020

The ladder-shaped polyether toxin gambierol anchors the gating machinery of Kv3.1 channels in the resting state

por Kopljar, Ivan, Labro, Alain J., de Block, Tessa, Rainier, Jon D., Tytgat, Jan, Snyders, Dirk J.
Publicado 2013

The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels

por Coonen, Laura, Mayeur, Evy, De Neuter, Nicolas, Snyders, Dirk J., Cuello, Luis G., Labro, Alain J.
Publicado 2020

Kv Channel Gating Requires a Compatible S4-S5 Linker and Bottom Part of S6, Constrained by Non-interacting Residues

por Labro, Alain J., Raes, Adam L., Grottesi, Alessandro, Van Hoorick, Diane, Sansom, Mark S.P., Snyders, Dirk J.
Publicado 2008

Constitutive, Basal, and β-Alanine-Mediated Activation of the Human Mas-Related G Protein-Coupled Receptor D Induces Release of the Inflammatory Cytokine IL-6 and Is Dependent on N...

por Arora, Rohit, Van Theemsche, Kenny M., Van Remoortel, Samuel, Snyders, Dirk J., Labro, Alain J., Timmermans, Jean-Pierre
Publicado 2021

Pharmacological Profile of the Sodium Current in Human Stem Cell-Derived Cardiomyocytes Compares to Heterologous Nav1.5+β1 Model

por Van de Sande, Dieter V., Kopljar, Ivan, Teisman, Ard, Gallacher, David J., Snyders, Dirk J., Lu, Hua Rong, Labro, Alain J.
Publicado 2019

The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels

por Coonen, Laura, Martinez-Morales, Evelyn, Van De Sande, Dieter V., Snyders, Dirk J., Cortes, D. Marien, Cuello, Luis G., Labro, Alain J.
Publicado 2022

The resting membrane potential of hSC-CM in a syncytium is more hyperpolarised than that of isolated cells

por Van de Sande, Dieter V., Kopljar, Ivan, Maaike, Alaerts, Teisman, Ard, Gallacher, David J., Bart, Loeys, Snyders, Dirk J., Leybaert, Luc, Lu, Hua Rong, Labro, Alain J.
Publicado 2021