Turning genome-wide association study findings into opportunities for drug repositioning

por Lau, Alexandria, So, Hon-Cheong
Publicado 2020

A Unifying Framework for Evaluating the Predictive Power of Genetic Variants Based on the Level of Heritability Explained

por So, Hon-Cheong, Sham, Pak C.
Publicado 2010

Robust Association Tests Under Different Genetic Models, Allowing for Binary or Quantitative Traits and Covariates

por So, Hon-Cheong, Sham, Pak C.
Publicado 2011

Improving polygenic risk prediction from summary statistics by an empirical Bayes approach

por So, Hon-Cheong, Sham, Pak C.
Publicado 2017

Prediction of Drug Targets for Specific Diseases Leveraging Gene Perturbation Data: A Machine Learning Approach

por Zhao, Kai, Shi, Yujia, So, Hon-Cheong
Publicado 2022

Analysis of genetic differences between psychiatric disorders: exploring pathways and cell types/tissues involved and ability to differentiate the disorders by polygenic scores

por Rao, Shitao, Yin, Liangying, Xiang, Yong, So, Hon-Cheong
Publicado 2021

Exploring Drugs and Vaccines Associated with Altered Risks and Severity of COVID-19: A UK Biobank Cohort Study of All ATC Level-4 Drug Categories Reveals Repositioning Opportunitie...

por Xiang, Yong, Wong, Kenneth Chi-Yin, So, Hon-Cheong
Publicado 2021

Correction: Analysis of genetic differences between psychiatric disorders: exploring pathways and cell types/tissues involved and ability to differentiate the disorders by polygeni...

por Rao, Shitao, Yin, Liangying, Xiang, Yong, So, Hon-Cheong
Publicado 2022

Estimating the Total Number of Susceptibility Variants Underlying Complex Diseases from Genome-Wide Association Studies

por So, Hon-Cheong, Yip, Benjamin H. K., Sham, Pak Chung
Publicado 2010

The genetic basis of onset age in schizophrenia: evidence and models

por Zhan, Na, Sham, Pak C., So, Hon-Cheong, Lui, Simon S. Y.
Publicado 2023

Uncovering Clinical Risk Factors and Predicting Severe COVID-19 Cases Using UK Biobank Data: Machine Learning Approach

por Wong, Kenneth Chi-Yin, Xiang, Yong, Yin, Liangying, So, Hon-Cheong
Publicado 2021

Contributions of common genetic variants to specific languages and to when a language is learned

por Wong, Patrick C. M., Kang, Xin, So, Hon-Cheong, Choy, Kwong Wai
Publicado 2022

ASPM-lexical tone association in speakers of a tone language: Direct evidence for the genetic-biasing hypothesis of language evolution

por Wong, Patrick C. M., Kang, Xin, Wong, Kay H. Y., So, Hon-Cheong, Choy, Kwong Wai, Geng, Xiujuan
Publicado 2020

Genome-Wide Search for SNP Interactions in GWAS Data: Algorithm, Feasibility, Replication Using Schizophrenia Datasets

por Lee, Kwan-Yeung, Leung, Kwong-Sak, Ma, Suk Ling, So, Hon Cheong, Huang, Dan, Tang, Nelson Leung-Sang, Wong, Man-Hon
Publicado 2020

The single-cell chromatin accessibility landscape in mouse perinatal testis development

por Suen, Hoi Ching, Rao, Shitao, Luk, Alfred Chun Shui, Zhang, Ruoyu, Yang, Lele, Qi, Huayu, So, Hon Cheong, Hobbs, Robin M, Lee, Tin-lap, Liao, Jinyue
Publicado 2023

Pathway-Specific Polygenic Scores Improve Cross-Ancestry Prediction of Psychosis and Clinical Outcomes

por Tubbs, Justin D., Leung, Perry B.M., Zhong, Yuanxin, Zhan, Na, Hui, Tomy C.K., Ho, Karen K.Y., Hung, Karen S.Y., Cheung, Eric F.C., So, Hon-Cheong, Lui, Simon S.Y., Sham, Pak C.
Publicado 2023

Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain

por Zhao, Lei, Li, Zhongqi, Vong, Joaquim S. L., Chen, Xinyi, Lai, Hei-Ming, Yan, Leo Y. C., Huang, Junzhe, Sy, Samuel K. H., Tian, Xiaoyu, Huang, Yu, Chan, Ho Yin Edwin, So, Hon-Cheong, Ng, Wai-Lung, Tang, Yamei, Lin, Wei-Jye, Mok, Vincent C. T., Ko, Ho
Publicado 2020

Shortened Leukocyte Telomere Length Is Associated With Glycemic Progression in Type 2 Diabetes: A Prospective and Mendelian Randomization Analysis

por Cheng, Feifei, Luk, Andrea O., Shi, Mai, Huang, Chuiguo, Jiang, Guozhi, Yang, Aimin, Wu, Hongjiang, Lim, Cadmon K.P., Tam, Claudia H.T., Fan, Baoqi, Lau, Eric S.H., Ng, Alex C.W., Wong, Kwun Kiu, Carroll, Luke, Lee, Heung Man, Kong, Alice P., Keech, Anthony C., Chow, Elaine, Joglekar, Mugdha V., Tsui, Stephen K.W., So, Wing Yee, So, Hon Cheong, Hardikar, Anandwardhan A., Jenkins, Alicia J., Chan, Juliana C.N., Ma, Ronald C.W.
Publicado 2022

Low copy number of the salivary amylase gene predisposes to obesity

por Falchi, Mario, Moustafa, Julia Sarah El-Sayed, Takousis, Petros, Pesce, Francesco, Bonnefond, Amélie, Andersson-Assarsson, Johanna C., Sudmant, Peter H., Dorajoo, Rajkumar, Al-Shafai, Mashael Nedham, Bottolo, Leonardo, Ozdemir, Erdal, So, Hon-Cheong, Davies, Robert W., Patrice, Alexandre, Dent, Robert, Mangino, Massimo, Hysi, Pirro G., Dechaume, Aurélie, Huyvaert, Marlène, Skinner, Jane, Pigeyre, Marie, Caiazzo, Robert, Raverdy, Violeta, Vaillant, Emmanuel, Field, Sarah, Balkau, Beverley, Marre, Michel, Visvikis-Siest, Sophie, Weill, Jacques, Poulain-Godefroy, Odile, Jacobson, Peter, Sjostrom, Lars, Hammond, Christopher J., Deloukas, Panos, Sham, Pak Chung, McPherson, Ruth, Lee, Jeannette, Tai, E. Shyong, Sladek, Robert, Carlsson, Lena M.S., Walley, Andrew, Eichler, Evan E., Pattou, Francois, Spector, Timothy D., Froguel, Philippe
Publicado 2014

Biological Insights From 108 Schizophrenia-Associated Genetic Loci

por Ripke, Stephan, Neale, Benjamin M, Corvin, Aiden, Walters, James TR, Farh, Kai-How, Holmans, Peter A, Lee, Phil, Bulik-Sullivan, Brendan, Collier, David A, Huang, Hailiang, Pers, Tune H, Agartz, Ingrid, Agerbo, Esben, Albus, Margot, Alexander, Madeline, Amin, Farooq, Bacanu, Silviu A, Begemann, Martin, Belliveau, Richard A, Bene, Judit, Bergen, Sarah E, Bevilacqua, Elizabeth, Bigdeli, Tim B, Black, Donald W, Bruggeman, Richard, Buccola, Nancy G, Buckner, Randy L, Byerley, William, Cahn, Wiepke, Cai, Guiqing, Campion, Dominique, Cantor, Rita M, Carr, Vaughan J, Carrera, Noa, Catts, Stanley V, Chambert, Kimberley D, Chan, Raymond CK, Chan, Ronald YL, Chen, Eric YH, Cheng, Wei, Cheung, Eric FC, Chong, Siow Ann, Cloninger, C Robert, Cohen, David, Cohen, Nadine, Cormican, Paul, Craddock, Nick, Crowley, James J, Curtis, David, Davidson, Michael, Davis, Kenneth L, Degenhardt, Franziska, Del Favero, Jurgen, Demontis, Ditte, Dikeos, Dimitris, Dinan, Timothy, Djurovic, Srdjan, Donohoe, Gary, Drapeau, Elodie, Duan, Jubao, Dudbridge, Frank, Durmishi, Naser, Eichhammer, Peter, Eriksson, Johan, Escott-Price, Valentina, Essioux, Laurent, Fanous, Ayman H, Farrell, Martilias S, Frank, Josef, Franke, Lude, Freedman, Robert, Freimer, Nelson B, Friedl, Marion, Friedman, Joseph I, Fromer, Menachem, Genovese, Giulio, Georgieva, Lyudmila, Giegling, Ina, Giusti-Rodríguez, Paola, Godard, Stephanie, Goldstein, Jacqueline I, Golimbet, Vera, Gopal, Srihari, Gratten, Jacob, de Haan, Lieuwe, Hammer, Christian, Hamshere, Marian L, Hansen, Mark, Hansen, Thomas, Haroutunian, Vahram, Hartmann, Annette M, Henskens, Frans A, Herms, Stefan, Hirschhorn, Joel N, Hoffmann, Per, Hofman, Andrea, Hollegaard, Mads V, Hougaard, David M, Ikeda, Masashi, Joa, Inge, Julià, Antonio, Kahn, René S, Kalaydjieva, Luba, Karachanak-Yankova, Sena, Karjalainen, Juha, Kavanagh, David, Keller, Matthew C, Kennedy, James L, Khrunin, Andrey, Kim, Yunjung, Klovins, Janis, Knowles, James A, Konte, Bettina, Kucinskas, Vaidutis, Kucinskiene, Zita Ausrele, Kuzelova-Ptackova, Hana, Kähler, Anna K, Laurent, Claudine, Lee, Jimmy, Lee, S Hong, Legge, Sophie E, Lerer, Bernard, Li, Miaoxin, Li, Tao, Liang, Kung-Yee, Lieberman, Jeffrey, Limborska, Svetlana, Loughland, Carmel M, Lubinski, Jan, Lönnqvist, Jouko, Macek, Milan, Magnusson, Patrik KE, Maher, Brion S, Maier, Wolfgang, Mallet, Jacques, Marsal, Sara, Mattheisen, Manuel, Mattingsdal, Morten, McCarley, Robert W, McDonald, Colm, McIntosh, Andrew M, Meier, Sandra, Meijer, Carin J, Melegh, Bela, Melle, Ingrid, Mesholam-Gately, Raquelle I, Metspalu, Andres, Michie, Patricia T, Milani, Lili, Milanova, Vihra, Mokrab, Younes, Morris, Derek W, Mors, Ole, Murphy, Kieran C, Murray, Robin M, Myin-Germeys, Inez, Müller-Myhsok, Bertram, Nelis, Mari, Nenadic, Igor, Nertney, Deborah A, Nestadt, Gerald, Nicodemus, Kristin K, Nikitina-Zake, Liene, Nisenbaum, Laura, Nordin, Annelie, O’Callaghan, Eadbhard, O’Dushlaine, Colm, O’Neill, F Anthony, Oh, Sang-Yun, Olincy, Ann, Olsen, Line, Van Os, Jim, Pantelis, Christos, Papadimitriou, George N, Papiol, Sergi, Parkhomenko, Elena, Pato, Michele T, Paunio, Tiina, Pejovic-Milovancevic, Milica, Perkins, Diana O, Pietiläinen, Olli, Pimm, Jonathan, Pocklington, Andrew J, Powell, John, Price, Alkes, Pulver, Ann E, Purcell, Shaun M, Quested, Digby, Rasmussen, Henrik B, Reichenberg, Abraham, Reimers, Mark A, Richards, Alexander L, Roffman, Joshua L, Roussos, Panos, Ruderfer, Douglas M, Salomaa, Veikko, Sanders, Alan R, Schall, Ulrich, Schubert, Christian R, Schulze, Thomas G, Schwab, Sibylle G, Scolnick, Edward M, Scott, Rodney J, Seidman, Larry J, Shi, Jianxin, Sigurdsson, Engilbert, Silagadze, Teimuraz, Silverman, Jeremy M, Sim, Kang, Slominsky, Petr, Smoller, Jordan W, So, Hon-Cheong, Spencer, Chris C A, Stahl, Eli A, Stefansson, Hreinn, Steinberg, Stacy, Stogmann, Elisabeth, Straub, Richard E, Strengman, Eric, Strohmaier, Jana, Stroup, T Scott, Subramaniam, Mythily, Suvisaari, Jaana, Svrakic, Dragan M, Szatkiewicz, Jin P, Söderman, Erik, Thirumalai, Srinivas, Toncheva, Draga, Tosato, Sarah, Veijola, Juha, Waddington, John, Walsh, Dermot, Wang, Dai, Wang, Qiang, Webb, Bradley T, Weiser, Mark, Wildenauer, Dieter B, Williams, Nigel M, Williams, Stephanie, Witt, Stephanie H, Wolen, Aaron R, Wong, Emily HM, Wormley, Brandon K, Xi, Hualin Simon, Zai, Clement C, Zheng, Xuebin, Zimprich, Fritz, Wray, Naomi R, Stefansson, Kari, Visscher, Peter M, Adolfsson, Rolf, Andreassen, Ole A, Blackwood, Douglas HR, Bramon, Elvira, Buxbaum, Joseph D, Børglum, Anders D, Cichon, Sven, Darvasi, Ariel, Domenici, Enrico, Ehrenreich, Hannelore, Esko, Tõnu, Gejman, Pablo V, Gill, Michael, Gurling, Hugh, Hultman, Christina M, Iwata, Nakao, Jablensky, Assen V, Jönsson, Erik G, Kendler, Kenneth S, Kirov, George, Knight, Jo, Lencz, Todd, Levinson, Douglas F, Li, Qingqin S, Liu, Jianjun, Malhotra, Anil K, McCarroll, Steven A, McQuillin, Andrew, Moran, Jennifer L, Mortensen, Preben B, Mowry, Bryan J, Nöthen, Markus M, Ophoff, Roel A, Owen, Michael J, Palotie, Aarno, Pato, Carlos N, Petryshen, Tracey L, Posthuma, Danielle, Rietschel, Marcella, Riley, Brien P, Rujescu, Dan, Sham, Pak C, Sklar, Pamela, St Clair, David, Weinberger, Daniel R, Wendland, Jens R, Werge, Thomas, Daly, Mark J, Sullivan, Patrick F, O’Donovan, Michael C
Publicado 2014