Brain-Derived Neurotrophic Factor Elevates Activating Transcription Factor 4 (ATF4) in Neurons and Promotes ATF4-Dependent Induction of Sesn2

por Liu, Jin, Amar, Fatou, Corona, Carlo, So, Raphaella W. L., Andrews, Stuart J., Nagy, Peter L., Shelanski, Michael L., Greene, Lloyd A.
Publicado 2018

The G51D SNCA mutation generates a slowly progressive α-synuclein strain in early-onset Parkinson’s disease

por Lau, Heather H. C., Martinez-Valbuena, Ivan, So, Raphaella W. L., Mehra, Surabhi, Silver, Nicholas R. G., Mao, Alison, Stuart, Erica, Schmitt-Ulms, Cian, Hyman, Bradley T., Ingelsson, Martin, Kovacs, Gabor G., Watts, Joel C.
Publicado 2023

Application of CRISPR genetic screens to investigate neurological diseases

por So, Raphaella W. L., Chung, Sai Wai, Lau, Heather H. C., Watts, Jeremy J., Gaudette, Erin, Al-Azzawi, Zaid A. M., Bishay, Jossana, Lin, Lilian Tsai-Wei, Joung, Julia, Wang, Xinzhu, Schmitt-Ulms, Gerold
Publicado 2019

Alpha-synuclein seeding shows a wide heterogeneity in multiple system atrophy

por Martinez-Valbuena, Ivan, Visanji, Naomi P., Kim, Ain, Lau, Heather H. C., So, Raphaella W. L., Alshimemeri, Sohaila, Gao, Andrew, Seidman, Michael A., Luquin, Maria R., Watts, Joel C., Lang, Anthony E., Kovacs, Gabor G.
Publicado 2022

α-Synuclein Strains Target Distinct Brain Regions and Cell Types

por Lau, Angus, So, Raphaella W.L., Lau, Heather H.C., Sang, Jason C., Ruiz-Riquelme, Alejandro, Fleck, Shelaine C., Stuart, Erica, Menon, Sindhu, Visanji, Naomi P., Meisl, Georg, Faidi, Rania, Marano, Maria M., Schmitt-Ulms, Cian, Wang, Zhilan, Fraser, Paul E., Tandon, Anurag, Hyman, Bradley T., Wille, Holger, Ingelsson, Martin, Klenerman, David, Watts, Joel C.
Publicado 2019