Matrix Metalloproteinase-10/TIMP-2 Structure and Analyses Define Conserved Core Interactions and Diverse Exosite Interactions in MMP/TIMP Complexes

por Batra, Jyotica, Soares, Alexei S., Mehner, Christine, Radisky, Evette S.
Publicado 2013

Structural insights of non-canonical U•U pair and Hoogsteen interaction probed with Se atom

por Sheng, Jia, Gan, Jianhua, Soares, Alexei S., Salon, Jozef, Huang, Zhen
Publicado 2013

Structure of the dihydrolipoamide succinyltransferase catalytic domain from Escherichia coli in a novel crystal form: a tale of a common protein crystallization contaminant

por Andi, Babak, Soares, Alexei S., Shi, Wuxian, Fuchs, Martin R., McSweeney, Sean, Liu, Qun
Publicado 2019

Synthesis, structure and imaging of oligodeoxyribonucleotides with tellurium-nucleobase derivatization

por Sheng, Jia, Hassan, Abdalla E. A., Zhang, Wen, Zhou, Jianfeng, Xu, Bingqian, Soares, Alexei S., Huang, Zhen
Publicado 2011

Small molecule inhibitors of mesotrypsin from a structure-based docking screen

por Kayode, Olumide, Huang, Zunnan, Soares, Alexei S., Caulfield, Thomas R., Dong, Zigang, Bode, Ann M., Radisky, Evette S.
Publicado 2017

Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site

por Carra, John H, McHugh, Colleen A, Mulligan, Sheila, Machiesky, LeeAnn M, Soares, Alexei S, Millard, Charles B
Publicado 2007

Hydrogen bond formation between the naturally modified nucleobase and phosphate backbone

por Sheng, Jia, Zhang, Wen, Hassan, Abdalla E. A., Gan, Jianhua, Soares, Alexei S., Geng, Song, Ren, Yi, Huang, Zhen
Publicado 2012

Structural analysis and biochemical properties of laccase enzymes from two Pediococcus species

por Olmeda, Isidoro, Casino, Patricia, Collins, Robert E., Sendra, Ramón, Callejón, Sara, Huesa, Juanjo, Soares, Alexei S., Ferrer, Sergi, Pardo, Isabel
Publicado 2021

Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II

por Miller, Michelle S., Maheshwari, Sweta, Shi, Wuxian, Gao, Yuan, Chu, Nam, Soares, Alexei S., Cole, Philip A., Amzel, L. Mario, Fuchs, Martin R., Jakoncic, Jean, Gabelli, Sandra B.
Publicado 2019

A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs

por Nguyen, Thu, Phan, Kim L., Kozakov, Dima, Gabelli, Sandra B., Kreitler, Dale F., Andrews, Lawrence C., Jakoncic, Jean, Sweet, Robert M., Soares, Alexei S., Bernstein, Herbert J.
Publicado 2022

Solvent minimization induces preferential orientation and crystal clustering in serial micro-crystallography on micro-meshes, in situ plates and on a movable crystal conveyor belt

por Soares, Alexei S., Mullen, Jeffrey D., Parekh, Ruchi M., McCarthy, Grace S., Roessler, Christian G., Jackimowicz, Rick, Skinner, John M., Orville, Allen M., Allaire, Marc, Sweet, Robert M.
Publicado 2014

A simple technique to reduce evaporation of crystallization droplets by using plate lids with apertures for adding liquids

por Zipper, Lauren E., Aristide, Xavier, Bishop, Dylan P., Joshi, Ishita, Kharzeev, Julia, Patel, Krishna B., Santiago, Brianna M., Joshi, Karan, Dorsinvil, Kahille, Sweet, Robert M., Soares, Alexei S.
Publicado 2014

Best practices for high data-rate macromolecular crystallography (HDRMX)

por Bernstein, Herbert J., Andrews, Lawrence C., Diaz, Jorge A., Jakoncic, Jean, Nguyen, Thu, Sauter, Nicholas K., Soares, Alexei S., Wei, Justin Y., Wlodek, Maciej R., Xerri, Mario A.
Publicado 2020

High-speed raster-scanning synchrotron serial microcrystallography with a high-precision piezo-scanner

por Gao, Yuan, Xu, Weihe, Shi, Wuxian, Soares, Alexei, Jakoncic, Jean, Myers, Stuart, Martins, Bruno, Skinner, John, Liu, Qun, Bernstein, Herbert, McSweeney, Sean, Nazaretski, Evgeny, Fuchs, Martin R.
Publicado 2018

Acoustic transfer of protein crystals from agarose pedestals to micromeshes for high-throughput screening

por Cuttitta, Christina M., Ericson, Daniel L., Scalia, Alexander, Roessler, Christian G., Teplitsky, Ella, Joshi, Karan, Campos, Olven, Agarwal, Rakhi, Allaire, Marc, Orville, Allen M., Sweet, Robert M., Soares, Alexei S.
Publicado 2015

Using sound pulses to solve the crystal-harvesting bottleneck

por Samara, Yasmin N., Brennan, Haley M., McCarthy, Liam, Bollard, Mary T., Laspina, Denise, Wlodek, Jakub M., Campos, Stefanie L., Natarajan, Ramya, Gofron, Kazimierz, McSweeney, Sean, Soares, Alexei S., Leroy, Ludmila
Publicado 2018

Serial crystallography with multi-stage merging of thousands of images

por Soares, Alexei S., Yamada, Yusuke, Jakoncic, Jean, McSweeney, Sean, Sweet, Robert M., Skinner, John, Foadi, James, Fuchs, Martin R., Schneider, Dieter K., Shi, Wuxian, Andi, Babak, Andrews, Lawrence C., Bernstein, Herbert J.
Publicado 2022

Hitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes

por Yin, Xingyu, Scalia, Alexander, Leroy, Ludmila, Cuttitta, Christina M., Polizzo, Gina M., Ericson, Daniel L., Roessler, Christian G., Campos, Olven, Ma, Millie Y., Agarwal, Rakhi, Jackimowicz, Rick, Allaire, Marc, Orville, Allen M., Sweet, Robert M., Soares, Alexei S.
Publicado 2014

Hepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease

por Andi, Babak, Kumaran, Desigan, Kreitler, Dale F., Soares, Alexei S., Keereetaweep, Jantana, Jakoncic, Jean, Lazo, Edwin O., Shi, Wuxian, Fuchs, Martin R., Sweet, Robert M., Shanklin, John, Adams, Paul D., Schmidt, Jurgen G., Head, Martha S., McSweeney, Sean
Publicado 2022

A Linear Relationship between Crystal Size and Fragment Binding Time Observed Crystallographically: Implications for Fragment Library Screening Using Acoustic Droplet Ejection

por Cole, Krystal, Roessler, Christian G., Mulé, Elizabeth A., Benson-Xu, Emma J., Mullen, Jeffrey D., Le, Benjamin A., Tieman, Alanna M., Birone, Claire, Brown, Maria, Hernandez, Jesus, Neff, Sherry, Williams, Daniel, Allaire, Marc, Orville, Allen M., Sweet, Robert M., Soares, Alexei S.
Publicado 2014