Antitubercular 2-Pyrazolylpyrimidinones: Structure–Activity Relationship and Mode-of-Action Studies

por Soares de Melo, Candice, Singh, Vinayak, Myrick, Alissa, Simelane, Sandile B., Taylor, Dale, Brunschwig, Christel, Lawrence, Nina, Schnappinger, Dirk, Engelhart, Curtis A., Kumar, Anuradha, Parish, Tanya, Su, Qin, Myers, Timothy G., Boshoff, Helena I. M., Barry, Clifton E., Sirgel, Frederick A., van Helden, Paul D., Buchanan, Kirsteen I., Bayliss, Tracy, Green, Simon R., Ray, Peter C., Wyatt, Paul G., Basarab, Gregory S., Eyermann, Charles J., Chibale, Kelly, Ghorpade, Sandeep R.
Publicado 2021

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure–Activity Relationships, Mechanism of Action and Absorption, Distribu...

por Murugesan, Dinakaran, Ray, Peter C., Bayliss, Tracy, Prosser, Gareth A., Harrison, Justin R., Green, Kirsteen, Soares de Melo, Candice, Feng, Tzu-Shean, Street, Leslie J., Chibale, Kelly, Warner, Digby F., Mizrahi, Valerie, Epemolu, Ola, Scullion, Paul, Ellis, Lucy, Riley, Jennifer, Shishikura, Yoko, Ferguson, Liam, Osuna-Cabello, Maria, Read, Kevin D., Green, Simon R., Lamprecht, Dirk A., Finin, Peter M., Steyn, Adrie J. C., Ioerger, Thomas R., Sacchettini, Jim, Rhee, Kyu Y., Arora, Kriti, Barry, Clifton E., Wyatt, Paul G., Boshoff, Helena I. M.
Publicado 2018

Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure–Activity Relationship and Target I...

por Wilson, Colin R., Gessner, Richard K., Moosa, Atica, Seldon, Ronnett, Warner, Digby F., Mizrahi, Valerie, Soares de Melo, Candice, Simelane, Sandile B., Nchinda, Aloysius, Abay, Efrem, Taylor, Dale, Njoroge, Mathew, Brunschwig, Christel, Lawrence, Nina, Boshoff, Helena I. M., Barry, Clifton E., Sirgel, Frederick A., van Helden, Paul, Harris, C. John, Gordon, Richard, Ghidelli-Disse, Sonja, Pflaumer, Hannah, Boesche, Markus, Drewes, Gerard, Sanz, Olalla, Santos, Gracia, Rebollo-Lopez, Maria José, Urones, Beatriz, Selenski, Carolyn, Lafuente-Monasterio, Maria Jose, Axtman, Matthew, Lelièvre, Joël, Ballell, Lluis, Mueller, Rudolf, Street, Leslie J., Ghorpade, Sandeep R., Chibale, Kelly
Publicado 2017