Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment

por Wang, Kai, Schriver, Brian J., Aschar-Sobbi, Roozbeh, Yi, Alex Y., Feric, Nicole T., Graziano, Michael P.
Publicado 2023

Acute effects of cardiac contractility modulation stimulation in conventional 2D and 3D human induced pluripotent stem cell-derived cardiomyocyte models

por Feaster, Tromondae K., Feric, Nicole, Pallotta, Isabella, Narkar, Akshay, Casciola, Maura, Graziano, Michael P., Aschar-Sobbi, Roozbeh, Blinova, Ksenia
Publicado 2022

Complex interactions in a novel SCN5A compound mutation associated with long QT and Brugada syndrome: Implications for Na(+) channel blocking pharmacotherapy for de novo conduction...

por Liu, Jie, Bayer, Jason D., Aschar-Sobbi, Roozbeh, Wauchop, Marianne, Spears, Danna, Gollob, Michael, Vigmond, Edward J., Tsushima, Robert, Backx, Peter H., Chauhan, Vijay S.
Publicado 2018

Constitutive smooth muscle tumour necrosis factor regulates microvascular myogenic responsiveness and systemic blood pressure

por Kroetsch, Jeffrey T., Levy, Andrew S., Zhang, Hangjun, Aschar-Sobbi, Roozbeh, Lidington, Darcy, Offermanns, Stefan, Nedospasov, Sergei A., Backx, Peter H., Heximer, Scott P., Bolz, Steffen-Sebastian
Publicado 2017

Engineered Cardiac Tissues Generated in the Biowire II: A Platform for Human-Based Drug Discovery

por Feric, Nicole T, Pallotta, Isabella, Singh, Rishabh, Bogdanowicz, Danielle R, Gustilo, Marietta M, Chaudhary, Khuram W, Willette, Robert N, Chendrimada, Tim P, Xu, Xiaoping, Graziano, Michael P, Aschar-Sobbi, Roozbeh
Publicado 2019

Biowire: a new platform for maturation of human pluripotent stem cell derived cardiomyocytes

por Nunes, Sara S., Miklas, Jason W., Liu, Jie, Aschar-Sobbi, Roozbeh, Xiao, Yun, Zhang, Boyang, Jiang, Jiahua, Masse, Stephane, Gagliardi, Mark, Hsieh, Anne, Thavandiran, Nimalan, Laflamme, Michael A., Nanthakumar, Kumaraswamy, Gross, Gil, Backx, Peter H., Keller, Gordon, Radisic, Milica
Publicado 2013

CFTR Therapeutics Normalize Cerebral Perfusion Deficits in Mouse Models of Heart Failure and Subarachnoid Hemorrhage

por Lidington, Darcy, Fares, Jessica C., Uhl, Franziska E., Dinh, Danny D., Kroetsch, Jeffrey T., Sauvé, Meghan, Malik, Firhan A., Matthes, Frank, Vanherle, Lotte, Adel, Arman, Momen, Abdul, Zhang, Hangjun, Aschar-Sobbi, Roozbeh, Foltz, Warren D., Wan, Hoyee, Sumiyoshi, Manabu, Macdonald, R. Loch, Husain, Mansoor, Backx, Peter H., Heximer, Scott P., Meissner, Anja, Bolz, Steffen-Sebastian
Publicado 2019

Blood pressure regulation by CD4(+) lymphocytes expressing choline acetyltransferase

por Olofsson, Peder S., Steinberg, Benjamin E., Sobbi, Roozbeh, Cox, Maureen A., Ahmed, Mohamed N., Oswald, Michaela, Szekeres, Ferenc, Hanes, William M., Introini, Andrea, Liu, Shu Fang, Holodick, Nichol E., Rothstein, Thomas L., Lövdahl, Cecilia, Chavan, Sangeeta S., Yang, Huan, Pavlov, Valentin A., Broliden, Kristina, Andersson, Ulf, Diamond, Betty, Miller, Edmund J., Arner, Anders, Gregersen, Peter K., Backx, Peter H., Mak, Tak W., Tracey, Kevin J.
Publicado 2016