Discovery of a Small Molecule Agonist of Phosphatidylinositol 3-Kinase p110α That Reactivates Latent HIV-1

por Doyon, Geneviève, Sobolewski, Michele D., Huber, Kelly, McMahon, Deborah, Mellors, John W., Sluis-Cremer, Nicolas
Publicado 2014

Rapid determination of SARS-CoV-2 antibody neutralization titer using Bio-Rad Bio-Plex correlates strongly with pseudovirus-determined neutralization titer

por Heaps, Amy L., Sobolewski, Michele D., Jacobs, Jana L., Gordon, Kelley C., Haidar, Ghady, Mellors, John W., Parikh, Urvi M.
Publicado 2023

Ex vivo activation of CD4(+) T-cells from donors on suppressive ART can lead to sustained production of infectious HIV-1 from a subset of infected cells

por Bui, John K., Halvas, Elias K., Fyne, Elizabeth, Sobolewski, Michele D., Koontz, Dianna, Shao, Wei, Luke, Brian, Hong, Feiyu F., Kearney, Mary F., Mellors, John W.
Publicado 2017

Comparison of methods to quantify inducible HIV-1 outgrowth

por Enick, P. Nathan, Brooker, Joseph P., Tumiotto, Camille M., Staines, Brittany T., Eron, Joseph J., McMahon, Deborah K., Gandhi, Rajesh T., Mellors, John W., Sobolewski, Michele D.
Publicado 2021

Proviruses with identical sequences comprise a large fraction of the replication-competent HIV reservoir

por Bui, John K., Sobolewski, Michele D., Keele, Brandon F., Spindler, Jonathan, Musick, Andrew, Wiegand, Ann, Luke, Brian T., Shao, Wei, Hughes, Stephen H., Coffin, John M., Kearney, Mary F., Mellors, John W.
Publicado 2017

Integration in oncogenes plays only a minor role in determining the in vivo distribution of HIV integration sites before or during suppressive antiretroviral therapy

por Coffin, John M., Bale, Michael J., Wells, Daria, Guo, Shuang, Luke, Brian, Zerbato, Jennifer M., Sobolewski, Michele D., Sia, Twan, Shao, Wei, Wu, Xiaolin, Maldarelli, Frank, Kearney, Mary F., Mellors, John W., Hughes, Stephen H.
Publicado 2021

Antibody Responses After mRNA-Based COVID-19 Vaccination in Residential Older Adults: Implications for Reopening

por Nace, David A., Kip, Kevin E., Mellors, John W., Peck Palmer, Octavia M., Shurin, Michael R., Mulvey, Katie, Crandall, Melissa, Sobolewski, Michele D., Enick, P. Nathan, McCormick, Kevin D., Jacobs, Jana L., Kane, April L., Lukanski, Amy, Kip, Paula L., Wells, Alan
Publicado 2021

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

por Rosenbloom, Daniel I. S., Bacchetti, Peter, Stone, Mars, Deng, Xutao, Bosch, Ronald J., Richman, Douglas D., Siliciano, Janet D., Mellors, John W., Deeks, Steven G., Ptak, Roger G., Hoh, Rebecca, Keating, Sheila M., Dimapasoc, Melanie, Massanella, Marta, Lai, Jun, Sobolewski, Michele D., Kulpa, Deanna A., Busch, Michael P.
Publicado 2019

HIV Infected T Cells Can Proliferate in vivo Without Inducing Expression of the Integrated Provirus

por Musick, Andrew, Spindler, Jonathan, Boritz, Eli, Pérez, Liliana, Crespo-Vélez, Daniel, Patro, Sean C., Sobolewski, Michele D., Bale, Michael J., Reid, Carolyn, Keele, Brandon F., Capoferri, Adam, Shao, Wei, Wiegand, Ann, Simonetti, Francesco R., Mellors, John W., Hughes, Stephen H., Coffin, John M., Maldarelli, Frank, Kearney, Mary F.
Publicado 2019

SARS-CoV-2 variants of concern: spike protein mutational analysis and epitope for broad neutralization

por Mannar, Dhiraj, Saville, James W., Sun, Zehua, Zhu, Xing, Marti, Michelle M., Srivastava, Shanti S., Berezuk, Alison M., Zhou, Steven, Tuttle, Katharine S., Sobolewski, Michele D., Kim, Andrew, Treat, Benjamin R., Da Silva Castanha, Priscila Mayrelle, Jacobs, Jana L., Barratt-Boyes, Simon M., Mellors, John W., Dimitrov, Dimiter S., Li, Wei, Subramaniam, Sriram
Publicado 2022

Rapid Emergence of Potentially Transmissible Severe Acute Respiratory Syndrome Coronavirus 2 With Resistance to Combination Monoclonal Antibody Therapy

por Jacobs, Jana L, Haidar, Ghady, Naqvi, Asma, McCormick, Kevin D, Sobolewski, Michele, Treat, Benjamin R, Heaps, Amy L, Simpson, Jordan, Kramer, Kailey Hughes, McCreary, Erin, Bariola, J Ryan, Klamar-Blain, Cynthia, Macatangay, Bernard J C, Dimitrov, Dimiter, Li, Wei, Marino, Christopher C, Raptis, Anastasios, Sethi, Rahil, Chandran, Uma, Barratt-Boyes, Simon, Parikh, Urvi M, Mellors, John W
Publicado 2023

Therapy With Allogeneic Severe Acute Respiratory Syndrome Coronavirus-2–Specific T Cells for Persistent Coronavirus Disease 2019 in Immunocompromised Patients

por Haidar, Ghady, Jacobs, Jana L, Kramer, Kailey Hughes, Naqvi, Asma, Heaps, Amy, Parikh, Urvi, McCormick, Kevin D, Sobolewski, Michele D, Agha, Mounzer, Bogdanovich, Tatiana, Bushunow, Vasilii, Farah, Rafic, Hensley, Matthew, Hsu, Yen-Michael S, Johnson, Bruce, Klamar-Blain, Cynthia, Kozar, Jennifer, Lendermon, Elizabeth, Macatangay, Bernard J C, Marino, Christopher C, Raptis, Anastasios, Salese, Erin, Silveira, Fernanda P, Leen, Ann M, Marshall, William L, Miller, Michael, Patel, Badrish, Atillasoy, Ercem, Mellors, John W
Publicado 2023

Potent Neutralization of Omicron and other SARS-CoV-2 Variants of Concern by Biparatopic Human VH Domains

por Chen, Chuan, Saville, James W., Marti, Michelle M., Schäfer, Alexandra, Cheng, Mary Hongying, Mannar, Dhiraj, Zhu, Xing, Berezuk, Alison M., Banerjee, Anupam, Sobolewski, Michele D., Kim, Andrew, Treat, Benjamin R., Da Silva Castanha, Priscila Mayrelle, Enick, Nathan, McCormick, Kevin D, Liu, Xianglei, Adams, Cynthia, Hines, Margaret Grace, Sun, Zehua, Chen, Weizao, Jacobs, Jana L., Barratt-Boyes, Simon M., Mellors, John W., Baric, Ralph S., Bahar, Ivet, Dimitrov, Dimiter S., Subramaniam, Sriram, Martinez, David R., Li, Wei
Publicado 2022

Potent and broad neutralization of SARS-CoV-2 variants of concern (VOCs) including omicron sub-lineages BA.1 and BA.2 by biparatopic human VH domains

por Chen, Chuan, Saville, James W., Marti, Michelle M., Schäfer, Alexandra, Cheng, Mary Hongying, Mannar, Dhiraj, Zhu, Xing, Berezuk, Alison M., Banerjee, Anupam, Sobolewski, Michele D., Kim, Andrew, Treat, Benjamin R., Da Silva Castanha, Priscila Mayrelle, Enick, Nathan, McCormick, Kevin D., Liu, Xianglei, Adams, Cynthia, Hines, Margaret Grace, Sun, Zehua, Chen, Weizao, Jacobs, Jana L., Barratt-Boyes, Simon M., Mellors, John W., Baric, Ralph S., Bahar, Ivet, Dimitrov, Dimiter S., Subramaniam, Sriram, Martinez, David R., Li, Wei
Publicado 2022

Intractable Coronavirus Disease 2019 (COVID-19) and Prolonged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Replication in a Chimeric Antigen Receptor-Modified T-Cel...

por Hensley, Matthew K, Bain, William G, Jacobs, Jana, Nambulli, Sham, Parikh, Urvi, Cillo, Anthony, Staines, Brittany, Heaps, Amy, Sobolewski, Michele D, Rennick, Linda J, Macatangay, Bernard J C, Klamar-Blain, Cynthia, Kitsios, Georgios D, Methé, Barbara, Somasundaram, Ashwin, Bruno, Tullia C, Cardello, Carly, Shan, Feng, Workman, Creg, Ray, Prabir, Ray, Anuradha, Lee, Janet, Sethi, Rahil, Schwarzmann, William E, Ladinsky, Mark S, Bjorkman, Pamela J, Vignali, Dario A, Duprex, W Paul, Agha, Mounzer E, Mellors, John W, McCormick, Kevin D, Morris, Alison, Haidar, Ghady
Publicado 2021