Taking Charge: Metal Ions Accelerate Amyloid Aggregation in Sequence Variants of α-Synuclein

por Byrd, Emily J., Wilkinson, Martin, Radford, Sheena E., Sobott, Frank
Publicado 2023

Signal loss due to oligomerization in ELISA analysis of amyloid-beta can be recovered by a novel sample pre-treatment method

por Janssen, Leen, Sobott, Frank, De Deyn, Peter P., Van Dam, Debby
Publicado 2015

Enhanced oligomerization of full-length RAGE by synergy of the interaction of its domains

por Moysa, Alexander, Hammerschmid, Dietmar, Szczepanowski, Roman H., Sobott, Frank, Dadlez, Michal
Publicado 2019

On-grid and in-flow mixing for time-resolved cryo-EM

por Klebl, David P., White, Howard D., Sobott, Frank, Muench, Stephen P.
Publicado 2021

High-Resolution Hydrogen–Deuterium Protection Factors from Sparse Mass Spectrometry Data Validated by Nuclear Magnetic Resonance Measurements

por Stofella, Michele, Skinner, Simon P., Sobott, Frank, Houwing-Duistermaat, Jeanine, Paci, Emanuele
Publicado 2022

Systematic simulation of the interactions of pleckstrin homology domains with membranes

por Le Huray, Kyle I. P., Wang, He, Sobott, Frank, Kalli, Antreas C.
Publicado 2022

Analysis of the PcrA-RNA polymerase complex reveals a helicase interaction motif and a role for PcrA/UvrD helicase in the suppression of R-loops

por Urrutia-Irazabal, Inigo, Ault, James R, Sobott, Frank, Savery, Nigel J, Dillingham, Mark S
Publicado 2021

It started with a Cys: Spontaneous cysteine modification during cryo-EM grid preparation

por Klebl, David P., Wang, Yiheng, Sobott, Frank, Thompson, Rebecca F., Muench, Stephen P.
Publicado 2022

Towards sub-millisecond cryo-EM grid preparation

por Klebl, David P., Kay, Robert W., Sobott, Frank, Kapur, Nikil, Muench, Stephen P.
Publicado 2022

Organization of the BcgI restriction–modification protein for the transfer of one methyl group to DNA

por Smith, Rachel M., Jacklin, Alistair J., Marshall, Jacqueline J. T., Sobott, Frank, Halford, Stephen E.
Publicado 2013

Type III restriction endonucleases are heterotrimeric: comprising one helicase–nuclease subunit and a dimeric methyltransferase that binds only one specific DNA

por Butterer, Annika, Pernstich, Christian, Smith, Rachel M., Sobott, Frank, Szczelkun, Mark D., Tóth, Júlia
Publicado 2014

Structural mechanism of synergistic activation of Aurora kinase B/C by phosphorylated INCENP

por Abdul Azeez, Kamal R., Chatterjee, Sneha, Yu, Channing, Golub, Todd R., Sobott, Frank, Elkins, Jonathan M.
Publicado 2019

Organization of the BcgI restriction-modification protein for the cleavage of eight phosphodiester bonds in DNA

por Smith, Rachel M., Marshall, Jacqueline J. T., Jacklin, Alistair J., Retter, Susan E., Halford, Stephen E., Sobott, Frank
Publicado 2013

Effects of Detergent on α-Synuclein Structure: A Native MS-Ion Mobility Study

por Moons, Rani, van der Wekken-de Bruijne, Renate, Maudsley, Stuart, Lemière, Filip, Lambeir, Anne-Marie, Sobott, Frank
Publicado 2020

Further insights from structural mass spectrometry into endocytosis adaptor protein assemblies

por Heidemann, Johannes, Kölbel, Knut, Konijnenberg, Albert, Van Dyck, Jeroen, Garcia-Alai, Maria, Meijers, Rob, Sobott, Frank, Uetrecht, Charlotte
Publicado 2020

Metal ions shape α-synuclein

por Moons, Rani, Konijnenberg, Albert, Mensch, Carl, Van Elzen, Roos, Johannessen, Christian, Maudsley, Stuart, Lambeir, Anne-Marie, Sobott, Frank
Publicado 2020

DNA binding by the antimalarial compound artemisinin

por Slavkovic, Sladjana, Shoara, Aron A., Churcher, Zachary R., Daems, Elise, de Wael, Karolien, Sobott, Frank, Johnson, Philip E.
Publicado 2022

Sizing up DNA nanostructure assembly with native mass spectrometry and ion mobility

por van Dyck, Jeroen F., Burns, Jonathan R., Le Huray, Kyle I. P., Konijnenberg, Albert, Howorka, Stefan, Sobott, Frank
Publicado 2022

A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT

por Talavera, Ariel, Tamman, Hedvig, Ainelo, Andres, Konijnenberg, Albert, Hadži, San, Sobott, Frank, Garcia-Pino, Abel, Hõrak, Rita, Loris, Remy
Publicado 2019

Specific and non-specific interactions of ParB with DNA: implications for chromosome segregation

por Taylor, James A., Pastrana, Cesar L., Butterer, Annika, Pernstich, Christian, Gwynn, Emma J., Sobott, Frank, Moreno-Herrero, Fernando, Dillingham, Mark S.
Publicado 2015