CryoEM structures of open dimers of gyrase A in complex with DNA illuminate mechanism of strand passage

por Soczek, Katarzyna M, Grant, Tim, Rosenthal, Peter B, Mondragón, Alfonso
Publicado 2018

CRISPR-Cas9 bends and twists DNA to read its sequence

por Cofsky, Joshua C., Soczek, Katarzyna M., Knott, Gavin J., Nogales, Eva, Doudna, Jennifer A.
Publicado 2022

Structure and flexibility of the yeast NuA4 histone acetyltransferase complex

por Zukin, Stefan A, Marunde, Matthew R, Popova, Irina K, Soczek, Katarzyna M, Nogales, Eva, Patel, Avinash B
Publicado 2022

Genome expansion by a CRISPR trimmer-integrase

por Wang, Joy Y., Tuck, Owen T., Skopintsev, Petr, Soczek, Katarzyna M., Li, Gary, Al-Shayeb, Basem, Zhou, Julia, Doudna, Jennifer A.
Publicado 2023

Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer

por Barger, Carter J., Suwala, Abigail K., Soczek, Katarzyna M., Wang, Albert S., Kim, Min Y., Hong, Chibo, Doudna, Jennifer A., Chang, Susan M., Phillips, Joanna J., Solomon, David A., Costello, Joseph F.
Publicado 2022

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage

por Amen, Alexandra M., Fellmann, Christof, Soczek, Katarzyna M., Ren, Shawn M., Lew, Rachel J., Knott, Gavin J., Park, Jesslyn E., McKinney, Andrew M., Mancini, Andrew, Doudna, Jennifer A., Costello, Joseph F.
Publicado 2021

Rapid assessment of SARS-CoV-2–evolved variants using virus-like particles

por Syed, Abdullah M., Taha, Taha Y., Tabata, Takako, Chen, Irene P., Ciling, Alison, Khalid, Mir M., Sreekumar, Bharath, Chen, Pei-Yi, Hayashi, Jennifer M., Soczek, Katarzyna M., Ott, Melanie, Doudna, Jennifer A.
Publicado 2021