Mending a broken heart: current strategies and limitations of cell-based therapy

por Liew, Lee Chuen, Ho, Beatrice Xuan, Soh, Boon-Seng
Publicado 2020

Translational stem cell therapy: vascularized skin grafts in skin repair and regeneration

por Phua, Qian Hua, Han, Hua Alexander, Soh, Boon-Seng
Publicado 2021

Disease Modeling Using 3D Organoids Derived from Human Induced Pluripotent Stem Cells

por Ho, Beatrice Xuan, Pek, Nicole Min Qian, Soh, Boon-Seng
Publicado 2018

Applications of miRNAs in cardiac development, disease progression and regeneration

por Pang, Jeremy Kah Sheng, Phua, Qian Hua, Soh, Boon-Seng
Publicado 2019

Mitigating off-target effects in CRISPR/Cas9-mediated in vivo gene editing

por Han, Hua Alexander, Pang, Jeremy Kah Sheng, Soh, Boon-Seng
Publicado 2020

Addressing challenges in the clinical applications associated with CRISPR/Cas9 technology and ethical questions to prevent its misuse

por Kang, Xiang Jin, Caparas, Chiong Isabella Noelle, Soh, Boon Seng, Fan, Yong
Publicado 2017

Organoid cultures of MELAS neural cells reveal hyperactive Notch signaling that impacts neurodevelopment

por Winanto, Khong, Zi Jian, Soh, Boon-Seng, Fan, Yong, Ng, Shi-Yan
Publicado 2020

Tocotrienol is a cardioprotective agent against ageing-associated cardiovascular disease and its associated morbidities

por Ramanathan, Nardev, Tan, Esther, Loh, Li Jun, Soh, Boon Seng, Yap, Wei Ney
Publicado 2018

In Vivo Genome Editing as a Therapeutic Approach

por Ho, Beatrice Xuan, Loh, Sharon Jia Hui, Chan, Woon Khiong, Soh, Boon Seng
Publicado 2018

Insights to Heart Development and Cardiac Disease Models Using Pluripotent Stem Cell Derived 3D Organoids

por Pang, Jeremy Kah Sheng, Ho, Beatrice Xuan, Chan, Woon-Khiong, Soh, Boon-Seng
Publicado 2021

3D Human Organoids: The Next “Viral” Model for the Molecular Basis of Infectious Diseases

por Chia, Shirley Pei Shan, Kong, Sharleen Li Ying, Pang, Jeremy Kah Sheng, Soh, Boon-Seng
Publicado 2022

Human germline editing: Insights to future clinical treatment of diseases

por Li, Yanni, Kang, Xiang Jin, Pang, Jeremy Kah Sheng, Soh, Boon Seng, Yu, Yang, Fan, Yong
Publicado 2018

Differentiation of Club Cells to Alveolar Epithelial Cells In Vitro

por Zheng, Dahai, Soh, Boon-Seng, Yin, Lu, Hu, Guangan, Chen, Qingfeng, Choi, Hyungwon, Han, Jongyoon, Chow, Vincent T. K., Chen, Jianzhu
Publicado 2017

Microhexagon gradient array directs spatial diversification of spinal motor neurons

por Lim, Geok Soon, Hor, Jin Hui, Ho, Nicholas R.Y., Wong, Chi Yan, Ng, Shi Yan, Soh, Boon Seng, Shao, Huilin
Publicado 2019

Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes

por Fan, Yong, Ho, Beatrice Xuan, Pang, Jeremy Kah Sheng, Pek, Nicole Min Qian, Hor, Jin Hui, Ng, Shi-Yan, Soh, Boon-Seng
Publicado 2018

Characterizing arrhythmia using machine learning analysis of Ca(2+) cycling in human cardiomyocytes

por Pang, Jeremy K.S., Chia, Sabrina, Zhang, Jinqiu, Szyniarowski, Piotr, Stewart, Colin, Yang, Henry, Chan, Woon-Khiong, Ng, Shi Yan, Soh, Boon-Seng
Publicado 2022

N-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironment

por Soh, Boon-Seng, Buac, Kristina, Xu, Huansheng, Li, Edward, Ng, Shi-Yan, Wu, Hao, Chmielowiec, Jolanta, Jiang, Xin, Bu, Lei, Li, Ronald A, Cowan, Chad, Chien, Kenneth R
Publicado 2014

Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy

por Hor, Jin Hui, Soh, Eunice Shi-Yi, Tan, Li Yi, Lim, Valerie Jing Wen, Santosa, Munirah Mohamad, Winanto, Ho, Beatrice Xuan, Fan, Yong, Soh, Boon-Seng, Ng, Shi-Yan
Publicado 2018

Mitochondrial 3243A > G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells

por Pek, Nicole Min Qian, Phua, Qian Hua, Ho, Beatrice Xuan, Pang, Jeremy Kah Sheng, Hor, Jin-Hui, An, Omer, Yang, Henry He, Yu, Yang, Fan, Yong, Ng, Shi-Yan, Soh, Boon-Seng
Publicado 2019

ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation

por Hor, Jin-Hui, Santosa, Munirah Mohamad, Lim, Valerie Jing Wen, Ho, Beatrice Xuan, Taylor, Amy, Khong, Zi Jian, Ravits, John, Fan, Yong, Liou, Yih-Cherng, Soh, Boon-Seng, Ng, Shi-Yan
Publicado 2020