Increasing the Potential of the Auristatin Cancer-Drug Family by Shifting the Conformational Equilibrium

por Sokka, Iris K., Ekholm, Filip S., Johansson, Mikael P.
Publicado 2019

Halogenation at the Phenylalanine Residue of Monomethyl Auristatin F Leads to a Favorable cis/trans Equilibrium and Retained Cytotoxicity

por Sokka, Iris K., Imlimthan, Surachet, Sarparanta, Mirkka, Maaheimo, Hannu, Johansson, Mikael P., Ekholm, Filip S.
Publicado 2021

Sweet Battle of the Epimers—Continued Exploration of Monosaccharide-Derived Delivery Agents for Boron Neutron Capture Therapy

por Matović, Jelena, Bahrami, Katayun, Stockmann, Philipp, Sokka, Iris K., Khng, You Cheng, Sarparanta, Mirkka, Hey-Hawkins, Evamarie, Rautio, Jarkko, Ekholm, Filip S.
Publicado 2023

Synthesis and In Vitro Evaluation of a Set of 6-Deoxy-6-thio-carboranyl d-Glucoconjugates Shed Light on the Substrate Specificity of the GLUT1 Transporter

por Matović, Jelena, Järvinen, Juulia, Sokka, Iris K., Stockmann, Philipp, Kellert, Martin, Imlimthan, Surachet, Sarparanta, Mirkka, Johansson, Mikael P., Hey-Hawkins, Evamarie, Rautio, Jarkko, Ekholm, Filip S.
Publicado 2022

Addressing the Biochemical Foundations of a Glucose-Based “Trojan Horse”-Strategy to Boron Neutron Capture Therapy: From Chemical Synthesis to In Vitro Assessment

por Matović, Jelena, Järvinen, Juulia, Bland, Helena C., Sokka, Iris K., Imlimthan, Surachet, Ferrando, Ruth Mateu, Huttunen, Kristiina M., Timonen, Juri, Peräniemi, Sirpa, Aitio, Olli, Airaksinen, Anu J., Sarparanta, Mirkka, Johansson, Mikael P., Rautio, Jarkko, Ekholm, Filip S.
Publicado 2020