Cell cycle responses to Topoisomerase II inhibition: Molecular mechanisms and clinical implications

por Soliman, Tanya N., Keifenheim, Daniel, Parker, Peter J., Clarke, Duncan J.
Publicado 2023

A cancer-associated, genome protective programme engaging PKCε

por Parker, Peter J., Lockwood, Nicola, Davis, Khalil, Kelly, Joanna R., Soliman, Tanya N., Pardo, Ainara Lopez, Marshall, Jacqueline J.T., Redmond, Joanna M., Vitale, Marco, Silvia Martini
Publicado 2020

The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition

por Kelly, Joanna R., Martini, Silvia, Brownlow, Nicola, Joshi, Dhira, Federico, Stefania, Jamshidi, Shirin, Kjaer, Svend, Lockwood, Nicola, Rahmen, Khondaker Miraz, Fraternali, Franca, Parker, Peter J., Soliman, Tanya N.
Publicado 2020

Author Correction: The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition

por Kelly, Joanna R., Martini, Silvia, Brownlow, Nicola, Joshi, Dhira, Federico, Stefania, Jamshidi, Shirin, Kjaer, Svend, Lockwood, Nicola, Rahman, Khondaker Miraz, Fraternali, Franca, Parker, Peter J., Soliman, Tanya N.
Publicado 2020

Genome-protective topoisomerase 2a-dependent G2 arrest requires p53 in hTERT-positive cancer cells

por Lockwood, Nicola, Martini, Silvia, Lopez-Pardo, Ainara, Deiss, Katharina, Segeren, Hendrika A., Semple, Robert K., Collins, Ian, Repana, Dimitra, Cobbaut, Mathias, Soliman, Tanya, Ciccarelli, Francesca, Parker, Peter J.
Publicado 2022

A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest

por Deiss, Katharina, Lockwood, Nicola, Howell, Michael, Segeren, Hendrika Alida, Saunders, Rebecca E, Chakravarty, Probir, Soliman, Tanya N, Martini, Silvia, Rocha, Nuno, Semple, Robert, Zalmas, Lykourgos-Panagiotis, Parker, Peter J
Publicado 2019

Co-ordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention

por Watson, Lisa, Soliman, Tanya N., Davis, Khalil, Kelly, Joanna, Lockwood, Nicola, Yang, Xiaoping, Lynham, Steven, Scott, John D., Crossland, Victoria, McDonald, Neil Q., Mann, David J., Armstrong, Alan, Eggert, Ulrike, Parker, Peter J.
Publicado 2021

Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface

por Claus, Jeroen, Patel, Gargi, Autore, Flavia, Colomba, Audrey, Weitsman, Gregory, Soliman, Tanya N, Roberts, Selene, Zanetti-Domingues, Laura C, Hirsch, Michael, Collu, Francesca, George, Roger, Ortiz-Zapater, Elena, Barber, Paul R, Vojnovic, Boris, Yarden, Yosef, Martin-Fernandez, Marisa L, Cameron, Angus, Fraternali, Franca, Ng, Tony, Parker, Peter J
Publicado 2018