The Hallmarks of Cancer as Ecologically Driven Phenotypes

por Somarelli, Jason A.
Publicado 2021

Dynamical modelling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity

por Subhadarshini, Seemadri, Sahoo, Sarthak, Debnath, Shibjyoti, Somarelli, Jason A., Jolly, Mohit Kumar
Publicado 2023

Dynamical modeling of proliferative-invasive plasticity and IFNγ signaling in melanoma reveals mechanisms of PD-L1 expression heterogeneity

por Subhadarshini, Seemadri, Sahoo, Sarthak, Debnath, Shibjyoti, Somarelli, Jason A, Jolly, Mohit Kumar
Publicado 2023

EMT and MET: necessary or permissive for metastasis?

por Jolly, Mohit Kumar, Ware, Kathryn E., Gilja, Shivee, Somarelli, Jason A., Levine, Herbert
Publicado 2017

Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?

por Jolly, Mohit Kumar, Tripathi, Satyendra C., Somarelli, Jason A., Hanash, Samir M., Levine, Herbert
Publicado 2017

Baby Genomics: Tracing the Evolutionary Changes That Gave Rise to Placentation

por Hao, Yue, Lee, Hyuk Jin, Baraboo, Michael, Burch, Katherine, Maurer, Taylor, Somarelli, Jason A, Conant, Gavin C
Publicado 2020

Analysis of immune subtypes across the epithelial-mesenchymal plasticity spectrum

por Chakraborty, Priyanka, Chen, Emily L., McMullen, Isabelle, Armstrong, Andrew J., Kumar Jolly, Mohit, Somarelli, Jason A.
Publicado 2021

Questions to guide cancer evolution as a framework for furthering progress in cancer research and sustainable patient outcomes

por Somarelli, Jason A., DeGregori, James, Gerlinger, Marco, Heng, Henry H., Marusyk, Andriy, Welch, Danny R., Laukien, Frank H.
Publicado 2022

KLF4 Induces Mesenchymal–Epithelial Transition (MET) by Suppressing Multiple EMT-Inducing Transcription Factors

por Subbalakshmi, Ayalur Raghu, Sahoo, Sarthak, McMullen, Isabelle, Saxena, Aaditya Narayan, Venugopal, Sudhanva Kalasapura, Somarelli, Jason A., Jolly, Mohit Kumar
Publicado 2021

Mapping phenotypic heterogeneity in melanoma onto the epithelial-hybrid-mesenchymal axis

por Pillai, Maalavika, Rajaram, Gouri, Thakur, Pradipti, Agarwal, Nilay, Muralidharan, Srinath, Ray, Ankita, Barbhaya, Dev, Somarelli, Jason A., Jolly, Mohit Kumar
Publicado 2022

Limb salvage versus amputation in patients with osteosarcoma of the extremities: an update in the modern era using the National Cancer Database

por Evans, Daniel R., Lazarides, Alexander L., Visgauss, Julia D., Somarelli, Jason A., Blazer, Dan G., Brigman, Brian E., Eward, William C.
Publicado 2020

Emergent dynamics of underlying regulatory network links EMT and androgen receptor-dependent resistance in prostate cancer

por Jindal, Rashi, Nanda, Abheepsa, Pillai, Maalavika, Ware, Kathryn E., Singh, Divyoj, Sehgal, Manas, Armstrong, Andrew J., Somarelli, Jason A., Jolly, Mohit Kumar
Publicado 2023

Development of a precision medicine pipeline to identify personalized treatments for colorectal cancer

por Altunel, Erdem, Roghani, Roham S., Chen, Kai-Yuan, Kim, So Young, McCall, Shannon, Ware, Kathryn E., Shen, Xiling, Somarelli, Jason A., Hsu, David S.
Publicado 2020

The ELF3 transcription factor is associated with an epithelial phenotype and represses epithelial-mesenchymal transition

por Subbalakshmi, Ayalur Raghu, Sahoo, Sarthak, Manjunatha, Prakruthi, Goyal, Shaurya, Kasiviswanathan, Vignesh A, Mahesh, Yeshwanth, Ramu, Soundharya, McMullen, Isabelle, Somarelli, Jason A., Jolly, Mohit Kumar
Publicado 2023

Allometric scaling of metabolic rate and cardiorespiratory variables in aquatic and terrestrial mammals

por He, Rebecca S., De Ruiter, Stacy, Westover, Tristan, Somarelli, Jason A., Blawas, Ashley M., Dayanidhi, Divya L., Singh, Ana, Steves, Benjamin, Driesinga, Samantha, Halsey, Lewis G., Fahlman, Andreas
Publicado 2023

Snail promotes resistance to enzalutamide through regulation of androgen receptor activity in prostate cancer

por Ware, Kathryn E., Somarelli, Jason A., Schaeffer, Daneen, Li, Jing, Zhang, Tian, Park, Sally, Patierno, Steven R., Freedman, Jennifer, Foo, Wen-Chi, Garcia, Mariano A., Armstrong, Andrew J.
Publicado 2016

An Integrative Systems Biology and Experimental Approach Identifies Convergence of Epithelial Plasticity, Metabolism, and Autophagy to Promote Chemoresistance

por Xu, Shengnan, Ware, Kathryn E., Ding, Yuantong, Kim, So Young, Sheth, Maya U., Rao, Sneha, Chan, Wesley, Armstrong, Andrew J., Eward, William C., Jolly, Mohit Kumar, Somarelli, Jason A.
Publicado 2019

Corrigendum: Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition

por Dayanidhi, Divya L., Somarelli, Jason A., Mantyh, John B., Rupprecht, Gabrielle, Roghani, Roham Salman, Vincoff, Sophia, Shin, Iljin, Zhao, Yiquan, Kim, So Young, McCall, Shannon, Hong, Jiyong, Hsu, David S.
Publicado 2023

Psymberin, a marine-derived natural product, induces cancer cell growth arrest and protein translation inhibition

por Dayanidhi, Divya L., Somarelli, Jason A., Mantyh, John B., Rupprecht, Gabrielle, Roghani, Roham Salman, Vincoff, Sophia, Shin, Iljin, Zhao, Yiquan, Kim, So Young, McCall, Shannon, Hong, Jiyong, Hsu, David S.
Publicado 2022

An integrated comparative physiology and molecular approach pinpoints mediators of breath-hold capacity in dolphins

por Blawas, Ashley M, Ware, Kathryn E, Schmaltz, Emma, Zheng, Larry, Spruance, Jacob, Allen, Austin S, West, Nicole, Devos, Nicolas, Corcoran, David L, Nowacek, Douglas P, Eward, William C, Fahlman, Andreas, Somarelli, Jason A
Publicado 2021