Defining the Role of Nuclear Factor (NF)-κB p105 Subunit in Human Macrophage by Transcriptomic Analysis of NFKB1 Knockout THP1 Cells

por Somma, Domenico, Kok, Fatma O., Kerrigan, David, Wells, Christine A., Carmody, Ruaidhrí J.
Publicado 2021

The IκB-protein BCL-3 controls Toll-like receptor-induced MAPK activity by promoting TPL-2 degradation in the nucleus

por Collins, Patricia E., Somma, Domenico, Kerrigan, David, Herrington, Felicity, Keeshan, Karen, Nibbs, Robert J. B., Carmody, Ruaidhrí J.
Publicado 2019

The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80

por Smith, Emma L, Somma, Domenico, Kerrigan, David, McIntyre, Zoe, Cole, John J, Liang, Kai Ling, Kiely, Patrick A, Keeshan, Karen, Carmody, Ruaidhrí J
Publicado 2019

The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits

por Mitxitorena, Izaskun, Somma, Domenico, Mitchell, Jennifer P., Lepistö, Matti, Tyrchan, Christian, Smith, Emma L., Kiely, Patrick A., Walden, Helen, Keeshan, Karen, Carmody, Ruaidhrí J.
Publicado 2020

miR-155-overexpressing monocytes resemble HLA(high)ISG15(+) synovial tissue macrophages from patients with rheumatoid arthritis and induce polyfunctional CD4(+) T-cell activation

por Olsson, Anton M, Povoleri, Giovanni A M, Somma, Domenico, Ridley, Michael L, Rizou, Tatiana, Lalnunhlimi, Sylvine, Macdonald, Lucy, Rajasekhar, Megha, Martinez-Nunez, Rocio T, Kurowska-Stolarska, Mariola, Taams, Leonie S
Publicado 2021

Sphingosine Kinases promote IL-17 expression in human T lymphocytes

por Barra, Giusi, Lepore, Alessio, Gagliardi, Miriam, Somma, Domenico, Matarazzo, Maria Rosaria, Costabile, Francesca, Pasquale, Giuseppe, Mazzoni, Alessio, Gallo, Carmela, Nuzzo, Genoveffa, Annunziato, Francesco, Fontana, Angelo, Leonardi, Antonio, De Palma, Raffaele
Publicado 2018

COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1(+) neutrophils and CD14(+) monocytes

por MacDonald, Lucy, Alivernini, Stefano, Tolusso, Barbara, Elmesmari, Aziza, Somma, Domenico, Perniola, Simone, Paglionico, Annamaria, Petricca, Luca, Bosello, Silvia L., Carfì, Angelo, Sali, Michela, Stigliano, Egidio, Cingolani, Antonella, Murri, Rita, Arena, Vincenzo, Fantoni, Massimo, Antonelli, Massimo, Landi, Francesco, Franceschi, Francesco, Sanguinetti, Maurizio, McInnes, Iain B., McSharry, Charles, Gasbarrini, Antonio, Otto, Thomas D., Kurowska-Stolarska, Mariola, Gremese, Elisa
Publicado 2021