DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain

por Abu Jhaisha, Samira, Widowati, Esti W., Kii, Isao, Sonamoto, Rie, Knapp, Stefan, Papadopoulos, Chrisovalantis, Becker, Walter
Publicado 2017

Identification of a DYRK1A Inhibitor that Induces Degradation of the Target Kinase using Co-chaperone CDC37 fused with Luciferase nanoKAZ

por Sonamoto, Rie, Kii, Isao, Koike, Yuka, Sumida, Yuto, Kato-Sumida, Tomoe, Okuno, Yukiko, Hosoya, Takamitsu, Hagiwara, Masatoshi
Publicado 2015

Selective inhibition of the kinase DYRK1A by targeting its folding process

por Kii, Isao, Sumida, Yuto, Goto, Toshiyasu, Sonamoto, Rie, Okuno, Yukiko, Yoshida, Suguru, Kato-Sumida, Tomoe, Koike, Yuka, Abe, Minako, Nonaka, Yosuke, Ikura, Teikichi, Ito, Nobutoshi, Shibuya, Hiroshi, Hosoya, Takamitsu, Hagiwara, Masatoshi
Publicado 2016