De novo design of stable proteins that efficaciously inhibit oncogenic G proteins

por Cummins, Matthew C., Tripathy, Ashutosh, Sondek, John, Kuhlman, Brian
Publicado 2023

Electrostatic and Functional Analysis of the Seven-Bladed WD β-Propellers

por Valeyev, Najl V., Downing, A. Kristina, Sondek, John, Deane, Charlotte
Publicado 2008

Designer proteins that competitively inhibit Gα(q) by targeting its effector site

por Hussain, Mahmud, Cummins, Matthew C., Endo-Streeter, Stuart, Sondek, John, Kuhlman, Brian
Publicado 2021

AvrRpm1 Missense Mutations Weakly Activate RPS2-Mediated Immune Response in Arabidopsis thaliana

por Cherkis, Karen A., Temple, Brenda R. S., Chung, Eui-Hwan, Sondek, John, Dangl, Jeffery L.
Publicado 2012

The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae

por Fernandez-Piñar, Pablo, Alemán, Ainel, Sondek, John, Dohlman, Henrik G., Molina, María, Martín, Humberto
Publicado 2012

Structural basis for the activation of PLC-γ isozymes by phosphorylation and cancer-associated mutations

por Hajicek, Nicole, Keith, Nicholas C, Siraliev-Perez, Edhriz, Temple, Brenda RS, Huang, Weigang, Zhang, Qisheng, Harden, T Kendall, Sondek, John
Publicado 2019

Multiplexed GTPase and GEF biosensor imaging enables network connectivity analysis

por Marston, Daniel J., Vilela, Marco, Huh, Jaewon, Ren, Jinqi, Azoitei, Mihai, Glekas, George, Danuser, Gaudenz, Sondek, John, Hahn, Klaus M.
Publicado 2020

Type III Effector Activation via Nucleotide Binding, Phosphorylation, and Host Target Interaction

por Desveaux, Darrell, Singer, Alex U, Wu, Ai-Jiuan, McNulty, Brian C, Musselwhite, Laura, Nimchuk, Zachary, Sondek, John, Dangl, Jeffery L
Publicado 2007

Correction: Type III Effector Activation via Nucleotide Binding, Phosphorylation, and Host Target Interaction

por Desveaux, Darrell, Singer, Alex U, Wu, Ai-Jiuan, McNulty, Brian C, Musslewhite, Laura, Nimchuk, Zachary, Sondek, John, Dangl, Jeffrey L
Publicado 2007

Dynamics of allosteric regulation of the phospholipase C-γ isozymes upon recruitment to membranes

por Siraliev-Perez, Edhriz, Stariha, Jordan TB, Hoffmann, Reece M, Temple, Brenda RS, Zhang, Qisheng, Hajicek, Nicole, Jenkins, Meredith L, Burke, John E, Sondek, John
Publicado 2022

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

por Azoitei, Mihai L., Noh, Jungsik, Marston, Daniel J., Roudot, Philippe, Marshall, Christopher B., Daugird, Timothy A., Lisanza, Sidney L., Sandí, María-José, Ikura, Mitsu, Sondek, John, Rottapel, Robert, Hahn, Klaus M., Danuser, Gaudenz
Publicado 2019

The experimental power of FR900359 to study Gq-regulated biological processes

por Schrage, Ramona, Schmitz, Anna-Lena, Gaffal, Evelyn, Annala, Suvi, Kehraus, Stefan, Wenzel, Daniela, Büllesbach, Katrin M., Bald, Tobias, Inoue, Asuka, Shinjo, Yuji, Galandrin, Ségolène, Shridhar, Naveen, Hesse, Michael, Grundmann, Manuel, Merten, Nicole, Charpentier, Thomas H., Martz, Matthew, Butcher, Adrian J., Slodczyk, Tanja, Armando, Sylvain, Effern, Maike, Namkung, Yoon, Jenkins, Laura, Horn, Velten, Stößel, Anne, Dargatz, Harald, Tietze, Daniel, Imhof, Diana, Galés, Céline, Drewke, Christel, Müller, Christa E., Hölzel, Michael, Milligan, Graeme, Tobin, Andrew B., Gomeza, Jesús, Dohlman, Henrik G., Sondek, John, Harden, T. Kendall, Bouvier, Michel, Laporte, Stéphane A., Aoki, Junken, Fleischmann, Bernd K., Mohr, Klaus, König, Gabriele M., Tüting, Thomas, Kostenis, Evi
Publicado 2015