Ubiquitin Ligases in Cholesterol Metabolism

por Jiang, Wei, Song, Bao-Liang
Publicado 2014

PAQR3 modulates cholesterol homeostasis by anchoring Scap/SREBP complex to the Golgi apparatus

por Xu, Daqian, Wang, Zheng, Zhang, Yuxue, Jiang, Wei, Pan, Yi, Song, Bao-Liang, Chen, Yan
Publicado 2015

The cation-π interaction in cysteine-rich domain of Smoothened is critical for its cholesterylation and function: The cation-π interaction is required for SMO cholesterylation

por Kong, Zekai, Xu, Min, Zhang, Yanqing, Huang, Wenda, Zhao, Xiaolu, Luo, Jie, Song, Bao-Liang
Publicado 2022

TMEM241 is a UDP-N-acetylglucosamine transporter required for M6P modification of NPC2 and cholesterol transport

por Zhao, Nan, Deng, Gang, Yuan, Pei-Xin, Zhang, Ya-Fen, Jiang, Lu-Yi, Zhao, Xiaolu, Song, Bao-Liang
Publicado 2023

Disruption of the ERLIN–TM6SF2–APOB complex destabilizes APOB and contributes to non-alcoholic fatty liver disease

por Li, Bo-Tao, Sun, Ming, Li, Yun-Feng, Wang, Ju-Qiong, Zhou, Zi-Mu, Song, Bao-Liang, Luo, Jie
Publicado 2020

SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1

por Wang, Ju-Qiong, Lin, Zi-Cun, Li, Liang-Liang, Zhang, Shao-Fang, Li, Wei-Hui, Liu, Wei, Song, Bao-Liang, Luo, Jie
Publicado 2020

Induction of senescence-associated secretory phenotype underlies the therapeutic efficacy of PRC2 inhibition in cancer

por Chu, Liping, Qu, Yuxiu, An, Yang, Hou, Linjun, Li, Juewan, Li, Weijia, Fan, Gaofeng, Song, Bao-Liang, Li, En, Zhang, Liye, Qi, Wei
Publicado 2022

Bile acids-mediated intracellular cholesterol transport promotes intestinal cholesterol absorption and NPC1L1 recycling

por Xiao, Jian, Dong, Le-Wei, Liu, Shuai, Meng, Fan-Hua, Xie, Chang, Lu, Xiao-Yi, Zhang, Weiping J., Luo, Jie, Song, Bao-Liang
Publicado 2023

Forward Genetic Screening for Regulators Involved in Cholesterol Synthesis Using Validation-Based Insertional Mutagenesis

por Jiang, Wei, Tang, Jing-Jie, Miao, Hong-Hua, Qu, Yu-Xiu, Qin, Jie, Xu, Jie, Yang, Jinbo, Li, Bo-Liang, Song, Bao-Liang
Publicado 2014

Schnyder corneal dystrophy-associated UBIAD1 mutations cause corneal cholesterol accumulation by stabilizing HMG-CoA reductase

por Jiang, Shi-You, Tang, Jing-Jie, Xiao, Xu, Qi, Wei, Wu, Suqian, Jiang, Chao, Hong, Jiaxu, Xu, Jianjiang, Song, Bao-Liang, Luo, Jie
Publicado 2019

POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

por Xiao, Jian, Xiong, Yanni, Yang, Liu-Ting, Wang, Ju-Qiong, Zhou, Zi-Mu, Dong, Le-Wei, Shi, Xiong-Jie, Zhao, Xiaolu, Luo, Jie, Song, Bao-Liang
Publicado 2020

Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2

por Zhou, Zhang-Sen, Li, Mei-Xin, Liu, Jie, Jiao, Hengwu, Xia, Jing-Ming, Shi, Xiong-Jie, Zhao, Huabin, Chu, Liping, Liu, Jingrong, Qi, Wei, Luo, Jie, Song, Bao-Liang
Publicado 2020

Cholesterol and fatty acids regulate cysteine ubiquitination of ACAT2 through competitive oxidation

por Wang, Yong-Jian, Bian, Yan, Luo, Jie, Lu, Ming, Xiong, Ying, Guo, Shu-Yuan, Yin, Hui-Yong, Lin, Xu, Li, Qin, Chang, Catherine CY, Chang, Ta-Yuan, Li, Bo-Liang, Song, Bao-Liang
Publicado 2017

Production of ACAT1 56-kDa isoform in human cells via trans-splicing involving the ampicillin resistance gene

por Hu, Guang-Jing, Chen, Jia, Zhao, Xiao-Nan, Xu, Jia-Jia, Guo, Dong-Qing, Lu, Ming, Zhu, Ming, Xiong, Ying, Li, Qin, Chang, Catherine CY, Song, Bao-Liang, Chang, Ta-Yuan, Li, Bo-Liang
Publicado 2013

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

por Jiang, Shi-You, Li, Hui, Tang, Jing-Jie, Wang, Jie, Luo, Jie, Liu, Bing, Wang, Jin-Kai, Shi, Xiong-Jie, Cui, Hai-Wei, Tang, Jie, Yang, Fan, Qi, Wei, Qiu, Wen-Wei, Song, Bao-Liang
Publicado 2018

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene

por Han, Yamei, Hu, Zhimin, Cui, Aoyuan, Liu, Zhengshuai, Ma, Fengguang, Xue, Yaqian, Liu, Yuxiao, Zhang, Feifei, Zhao, Zehua, Yu, Yanyan, Gao, Jing, Wei, Chun, Li, Jingya, Fang, Jing, Li, Jia, Fan, Jian-Gao, Song, Bao-Liang, Li, Yu
Publicado 2019

Identification, clinical manifestation and structural mechanisms of mutations in AMPK associated cardiac glycogen storage disease

por Hu, Dan, Hu, Dong, Liu, Liwen, Barr, Daniel, Liu, Yang, Balderrabano-Saucedo, Norma, Wang, Bo, Zhu, Feng, Xue, Yumei, Wu, Shulin, Song, BaoLiang, McManus, Heather, Murphy, Katherine, Loes, Katherine, Adler, Arnon, Monserrat, Lorenzo, Antzelevitch, Charles, Gollob, Michael H., Elliott, Perry M., Barajas-Martinez, Hector
Publicado 2020

Lipid-anchored proteasomes control membrane protein homeostasis

por Zhang, Ruizhu, Pan, Shuxian, Zheng, Suya, Liao, Qingqing, Jiang, Zhaodi, Wang, Dixian, Li, Xuemei, Hu, Ao, Li, Xinran, Zhu, Yezhang, Shen, Xiaoqi, Lei, Jing, Zhong, Siming, Zhang, Xiaomei, Huang, Lingyun, Wang, Xiaorong, Huang, Lan, Shen, Li, Song, Bao-Liang, Zhao, Jing-Wei, Wang, Zhiping, Yang, Bing, Guo, Xing
Publicado 2023