Accelerating expansion

por Sontheimer, Erik
Publicado 2015

Self vs. non-self discrimination during CRISPR RNA-directed immunity

por Marraffini, Luciano A., Sontheimer, Erik J.
Publicado 2010

SPO24 Is a Transcriptionally Dynamic, Small ORF-Encoding Locus Required for Efficient Sporulation in Saccharomyces cerevisiae

por Hurtado, Sara, Kim Guisbert, Karen S., Sontheimer, Erik J.
Publicado 2014

Template-jumping prime editing enables large insertion and exon rewriting in vivo

por Zheng, Chunwei, Liu, Bin, Dong, Xiaolong, Gaston, Nicholas, Sontheimer, Erik J., Xue, Wen
Publicado 2023

All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo

por Ibraheim, Raed, Song, Chun-Qing, Mir, Aamir, Amrani, Nadia, Xue, Wen, Sontheimer, Erik J.
Publicado 2018

Tetrazine-Ligated CRISPR sgRNAs for Efficient Genome Editing

por Chen, Zexiang, Devi, Gitali, Arif, Amena, Zamore, Phillip D., Sontheimer, Erik J., Watts, Jonathan K.
Publicado 2022

Tissue-restricted genome editing in vivo specified by microRNA-repressible anti-CRISPR proteins

por Lee, Jooyoung, Mou, Haiwei, Ibraheim, Raed, Liang, Shun-Qing, Liu, Pengpeng, Xue, Wen, Sontheimer, Erik J.
Publicado 2019

A Cas9 with PAM recognition for adenine dinucleotides

por Chatterjee, Pranam, Lee, Jooyoung, Nip, Lisa, Koseki, Sabrina R. T., Tysinger, Emma, Sontheimer, Erik J., Jacobson, Joseph M., Jakimo, Noah
Publicado 2020

Engineering Nme2Cas9 Adenine Base Editors with Improved Activity and Targeting Scope

por Bamidele, Nathan, Zhang, Han, Dong, Xiaolong, Gaston, Nicholas, Cheng, Haoyang, Kelly, Karen, Watts, Jonathan K., Xie, Jun, Gao, Guangping, Sontheimer, Erik J.
Publicado 2023

Orthogonal Cas9–Cas9 chimeras provide a versatile platform for genome editing

por Bolukbasi, Mehmet Fatih, Liu, Pengpeng, Luk, Kevin, Kwok, Samantha F., Gupta, Ankit, Amrani, Nadia, Sontheimer, Erik J., Zhu, Lihua Julie, Wolfe, Scot A.
Publicado 2018

Publisher Correction: Orthogonal Cas9-Cas9 chimeras provide a versatile platform for genome editing

por Bolukbasi, Mehmet Fatih, Liu, Pengpeng, Luk, Kevin, Kwok, Samantha F., Gupta, Ankit, Amrani, Nadia, Sontheimer, Erik J., Zhu, Lihua Julie, Wolfe, Scot A.
Publicado 2018

Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing

por Mir, Aamir, Alterman, Julia F., Hassler, Matthew R., Debacker, Alexandre J., Hudgens, Edward, Echeverria, Dimas, Brodsky, Michael H., Khvorova, Anastasia, Watts, Jonathan K., Sontheimer, Erik J.
Publicado 2018

C-BERST: Defining subnuclear proteomic landscapes at genomic elements with dCas9-APEX2

por Gao, Xin D., Tu, Li-Chun, Mir, Aamir, Rodriguez, Tomás, Ding, Yuehe, Leszyk, John, Dekker, Job, Shaffer, Scott A., Zhu, Lihua Julie, Wolfe, Scot A., Sontheimer, Erik J.
Publicado 2018

Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice

por Liu, Pengpeng, Liang, Shun-Qing, Zheng, Chunwei, Mintzer, Esther, Zhao, Yan G., Ponnienselvan, Karthikeyan, Mir, Aamir, Sontheimer, Erik J., Gao, Guangping, Flotte, Terence R., Wolfe, Scot A., Xue, Wen
Publicado 2021

Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins

por Lee, Jooyoung, Mir, Aamir, Edraki, Alireza, Garcia, Bianca, Amrani, Nadia, Lou, Hannah E., Gainetdinov, Ildar, Pawluk, April, Ibraheim, Raed, Gao, Xin D., Liu, Pengpeng, Davidson, Alan R., Maxwell, Karen L., Sontheimer, Erik J.
Publicado 2018

Genome-wide detection of CRISPR editing in vivo using GUIDE-tag

por Liang, Shun-Qing, Liu, Pengpeng, Smith, Jordan L., Mintzer, Esther, Maitland, Stacy, Dong, Xiaolong, Yang, Qiyuan, Lee, Jonathan, Haynes, Cole M., Zhu, Lihua Julie, Watts, Jonathan K., Sontheimer, Erik J., Wolfe, Scot A., Xue, Wen
Publicado 2022

Anti-CRISPR AcrIIA5 Potently Inhibits All Cas9 Homologs Used for Genome Editing

por Garcia, Bianca, Lee, Jooyoung, Edraki, Alireza, Hidalgo-Reyes, Yurima, Erwood, Steven, Mir, Aamir, Trost, Chantel N., Seroussi, Uri, Stanley, Sabrina Y., Cohn, Ronald D., Claycomb, Julie M., Sontheimer, Erik J., Maxwell, Karen L., Davidson, Alan R.
Publicado 2019

Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo

por Zhang, Han, Kelly, Karen, Lee, Jonathan, Echeverria, Dimas, Cooper, David, Panwala, Rebecca, Chen, Zexiang, Gaston, Nicholas, Newby, Gregory A., Xie, Jun, Liu, David R., Gao, Guangping, Wolfe, Scot A., Khvorova, Anastasia, Watts, Jonathan K., Sontheimer, Erik J.
Publicado 2023

Inhibition of CRISPR-Cas9 ribonucleoprotein complex assembly by anti-CRISPR AcrIIC2

por Thavalingam, Annoj, Cheng, Zhi, Garcia, Bianca, Huang, Xue, Shah, Megha, Sun, Wei, Wang, Min, Harrington, Lucas, Hwang, Sungwon, Hidalgo-Reyes, Yurima, Sontheimer, Erik J., Doudna, Jennifer, Davidson, Alan R., Moraes, Trevor F., Wang, Yanli, Maxwell, Karen L.
Publicado 2019

PAM-Flexible Genome Editing with an Engineered Chimeric Cas9

por Koseki, Sabrina, Hong, Lauren, Yudistyra, Vivian, Stan, Teodora, Tysinger, Emma, Silverstein, Rachel, Kramme, Christian, Amrani, Nadia, Savic, Natasha, Pacesa, Martin, Rodriguez, Tomás, Ponnapati, Manvitha, Jacobson, Joseph, Church, George, Truant, Ray, Jinek, Martin, Kleinstiver, Benjamin, Sontheimer, Erik, Chatterjee, Pranam
Publicado 2023