Identification and classification of differentially expressed genes reveal potential molecular signature associated with SARS-CoV-2 infection in lung adenocarcinomal cells

por Soremekun, Opeyemi S., Omolabi, Kehinde F., Soliman, Mahmoud E.S.
Publicado 2020

Update and Potential Opportunities in CBP [Cyclic Adenosine Monophosphate (cAMP) Response Element-Binding Protein (CREB)-Binding Protein] Research Using Computational Techniques

por Akinsiku, Oluwayimika E., Soremekun, Opeyemi S., Soliman, Mahmoud E. S.
Publicado 2021

An In Silico Functional Analysis of Non-Synonymous Single-Nucleotide Polymorphisms of Bovine CMAH Gene and Potential Implication in Pathogenesis

por Ogun, Oluwamayowa Joshua, Soremekun, Opeyemi S., Thaller, Georg, Becker, Doreen
Publicado 2023

Exploring the effect of ritonavir and TMC-310911 on SARS-CoV-2 and SARS-CoV main proteases: potential from a molecular perspective

por Soremekun, Opeyemi S, Omolabi, Kehinde F, Adewumi, Adeniyi T, Soliman, Mahmoud ES
Publicado 2020

Thompson loop: opportunities for antitubercular drug design by targeting the weak spot in demethylmenaquinone methyltransferase protein

por Adewumi, Adeniyi T., Soremekun, Opeyemi S., Ajadi, Mary B., Soliman, Mahmoud E. S.
Publicado 2020

Genome-Wide Association and Mendelian Randomization Analysis Reveal the Causal Relationship Between White Blood Cell Subtypes and Asthma in Africans

por Soremekun, Opeyemi, Soremekun, Chisom, Machipisa, Tafadzwa, Soliman, Mahmoud, Nashiru, Oyekanmi, Chikowore, Tinashe, Fatumo, Segun
Publicado 2021

Structural alterations in the catalytic core of hSIRT2 enzyme predict therapeutic benefits of Garcinia mangostana derivatives in Alzheimer's disease: molecular dynamics simulation...

por Akawa, Oluwole B., Subair, Temitayo I., Soremekun, Opeyemi S., Olotu, Fisayo A., Soliman, Mahmoud E. S.
Publicado 2021

Genetically Predicted Lipid Traits, Diabetes Mellitus Liability and Carotid Intima-media Thickness in African Ancestry Individuals: A Mendelian Randomization Study

por Soremekun, Opeyemi, Slob, Eric A. W., Burgess, Stephen, Boua, Palwende Romuald, Fatumo, Segun, Gill, Dipender
Publicado 2022

In-silico analysis reveals druggable single nucleotide polymorphisms in angiotensin 1 converting enzyme involved in the onset of blood pressure

por Udosen, Brenda, Soremekun, Opeyemi, Ekenna, Chinwe, Idowu Omotuyi, Olaposi, Chikowore, Tinashe, Nashiru, Oyekanmi, Fatumo, Segun
Publicado 2021

Benzimidazole compound abrogates SARS-COV-2 receptor-binding domain (RBD)/ACE2 interaction In vitro

por Omotuyi, Olaposi, Olatunji, Olusina M., Nash, Oyekanmi, Oyinloye, Babatunji, Soremekun, Opeyemi, Ijagbuji, Ayodeji, Fatumo, Segun
Publicado 2023

Leveraging information between multiple population groups and traits improves fine-mapping resolution

por Zhou, Feng, Soremekun, Opeyemi, Chikowore, Tinashe, Fatumo, Segun, Barroso, Inês, Morris, Andrew P., Asimit, Jennifer L.
Publicado 2023

Identification of promising high-affinity inhibitors of SARS-CoV-2 main protease from African Natural Products Databases by Virtual Screening

por DIABATE, Oudou, CISSE, Cheickna, SANGARE, Mamadou, Soremekun, Opeyemi, Fatumo, Segun, SHAFFER, Jeffrey G., DOUMBIA, Seydou, WELE, Mamadou
Publicado 2023

Phytomedicine in Disease Management: In-Silico Analysis of the Binding Affinity of Artesunate and Azadirachtin for Malaria Treatment

por Okoh, Michael P., Singla, Rajeev K., Madu, Chijioke, Soremekun, Opeyemi, Adejoh, Johnson, Alli, Lukman A., Shen, Bairong
Publicado 2021

Multivariate GWAS analysis reveals loci associated with liver functions in continental African populations

por Soremekun, Chisom, Machipisa, Tafadzwa, Soremekun, Opeyemi, Pirie, Fraser, Oyekanmi, Nashiru, Motala, Ayesha A., Chikowore, Tinashe, Fatumo, Segun
Publicado 2023

Meta-analysis of African ancestry genome-wide association studies identified novel locus and validates multiple loci associated with kidney function

por Kintu, Christopher, Soremekun, Opeyemi, Machipisa, Tafadzwa, Mayanja, Richard, Kalyesubula, Robert, Bagaya, Bernard S., Jjingo, Daudi, Chikowore, Tinashe, Fatumo, Segun
Publicado 2023

Molecular Dynamic Simulation Reveals Structure Differences in APOL1 Variants and Implication in Pathogenesis of Chronic Kidney Disease

por Mayanja, Richard, Kintu, Christopher, Diabate, Oudou, Soremekun, Opeyemi, Oluwagbemi, Olugbenga Oluseun, Wele, Mamadou, Kalyesubula, Robert, Jjingo, Daudi, Chikowore, Tinashe, Fatumo, Segun
Publicado 2022

Meta-Analysis and Multivariate GWAS Analyses in 77,850 Individuals of African Ancestry Identify Novel Variants Associated with Blood Pressure Traits

por Udosen, Brenda, Soremekun, Opeyemi, Kamiza, Abram, Machipisa, Tafadzwa, Cheickna, Cisse, Omotuyi, Olaposi, Soliman, Mahmoud, Wélé, Mamadou, Nashiru, Oyekanmi, Chikowore, Tinashe, Fatumo, Segun
Publicado 2023

Uganda Genome Resource: A rich research database for genomic studies of communicable and non-communicable diseases in Africa

por Fatumo, Segun, Mugisha, Joseph, Soremekun, Opeyemi S., Kalungi, Allan, Mayanja, Richard, Kintu, Christopher, Makanga, Ronald, Kakande, Ayoub, Abaasa, Andrew, Asiki, Gershim, Kalyesubula, Robert, Newton, Robert, Nyirenda, Moffat, Sandhu, Manj S., Kaleebu, Pontiano
Publicado 2022

Development of Halogenated Pyrazolines as Selective Monoamine Oxidase-B Inhibitors: Deciphering via Molecular Dynamics Approach

por Nair, Aathira Sujathan, Oh, Jong-Min, Koyiparambath, Vishal Payyalot, Kumar, Sunil, Sudevan, Sachithra Thazhathuveedu, Soremekun, Opeyemi, Soliman, Mahmoud E., Khames, Ahmed, Abdelgawad, Mohamed A., Pappachen, Leena K., Mathew, Bijo, Kim, Hoon
Publicado 2021

Transferability of genetic risk scores in African populations

por Kamiza, Abram B., Toure, Sounkou M., Vujkovic, Marijana, Machipisa, Tafadzwa, Soremekun, Opeyemi S., Kintu, Christopher, Corpas, Manuel, Pirie, Fraser, Young, Elizabeth, Gill, Dipender, Sandhu, Manjinder S., Kaleebu, Pontiano, Nyirenda, Moffat, Motala, Ayesha A., Chikowore, Tinashe, Fatumo, Segun
Publicado 2022