Shoc2 Is Targeted to Late Endosomes and Required for Erk1/2 Activation in EGF-Stimulated Cells

por Galperin, Emilia, Abdelmoti, Lina, Sorkin, Alexander
Publicado 2012

EGFR-RAS-MAPK signaling is confined to the plasma membrane and associated endorecycling protrusions

por Surve, Sachin, Watkins, Simon C., Sorkin, Alexander
Publicado 2021

Multiple mechanisms collectively regulate clathrin-mediated endocytosis of the epidermal growth factor receptor

por Goh, Lai Kuan, Huang, Fangtian, Kim, Woong, Gygi, Steven, Sorkin, Alexander
Publicado 2010

A Bifunctional Converter: Fluorescein Quenching scFv/Fluorogen Activating Protein for Photostability and Improved Signal to Noise in Fluorescence Experiments

por Saunders, Matthew J., Block, Ethan, Sorkin, Alexander, Waggoner, Alan S., Bruchez, Marcel P.
Publicado 2014

EGF receptor signaling, phosphorylation, ubiquitylation and endocytosis in tumors in vivo

por Pinilla-Macua, Itziar, Grassart, Alexandre, Duvvuri, Umamaheswar, Watkins, Simon C, Sorkin, Alexander
Publicado 2017

Small molecule induced oligomerization, clustering and clathrin-independent endocytosis of the dopamine transporter

por Sorkina, Tatiana, Ma, Shiqi, Larsen, Mads Breum, Watkins, Simon C, Sorkin, Alexander
Publicado 2018

Insights into the Modulation of Dopamine Transporter Function by Amphetamine, Orphenadrine, and Cocaine Binding

por Cheng, Mary Hongying, Block, Ethan, Hu, Feizhuo, Cobanoglu, Murat Can, Sorkin, Alexander, Bahar, Ivet
Publicado 2015

Endocytosis: A Turnover Mechanism Controlling Ion Channel Function

por Estadella, Irene, Pedrós-Gámez, Oriol, Colomer-Molera, Magalí, Bosch, Manel, Sorkin, Alexander, Felipe, Antonio
Publicado 2020

Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter

por Ma, Shiqi, Cheng, Mary H., Guthrie, Daryl A., Newman, Amy H., Bahar, Ivet, Sorkin, Alexander
Publicado 2017

Internalization of trophoblastic small extracellular vesicles and detection of their miRNA cargo in P-bodies

por Li, Hui, Pinilla-Macua, Itziar, Ouyang, Yingshi, Sadovsky, Elena, Kajiwara, Kazuhiro, Sorkin, Alexander, Sadovsky, Yoel
Publicado 2020

WASH and Tsg101/ALIX-dependent diversion of stress-internalized EGFR from the canonical endocytic pathway

por Tomas, Alejandra, Vaughan, Simon O., Burgoyne, Thomas, Sorkin, Alexander, Hartley, John A., Hochhauser, Daniel, Futter, Clare E.
Publicado 2015

Ubiquitination mediates Kv1.3 endocytosis as a mechanism for protein kinase C-dependent modulation

por Martínez-Mármol, Ramón, Styrczewska, Katarzyna, Pérez-Verdaguer, Mireia, Vallejo-Gracia, Albert, Comes, Núria, Sorkin, Alexander, Felipe, Antonio
Publicado 2017

Generation of endogenous pH-sensitive EGF receptor and its application in high-throughput screening for proteins involved in clathrin-mediated endocytosis

por Larsen, Mads Breum, Perez Verdaguer, Mireia, Schmidt, Brigitte F, Bruchez, Marcel P, Watkins, Simon C, Sorkin, Alexander
Publicado 2019

Localization dynamics of endogenous fluorescently labeled RAF1 in EGF-stimulated cells

por Surve, Sachin V., Myers, Paul J., Clayton, Samantha A., Watkins, Simon C., Lazzara, Matthew J., Sorkin, Alexander
Publicado 2019

Direct coupling of oligomerization and oligomerization-driven endocytosis of the dopamine transporter to its conformational mechanics and activity

por Sorkina, Tatiana, Cheng, Mary Hongying, Bagalkot, Tarique R., Wallace, Callen, Watkins, Simon C., Bahar, Ivet, Sorkin, Alexander
Publicado 2021

Mechanism of p38 MAPK–induced EGFR endocytosis and its crosstalk with ligand-induced pathways

por Perez Verdaguer, Mireia, Zhang, Tian, Paulo, Joao A., Gygi, Steven, Watkins, Simon C., Sakurai, Hiroaki, Sorkin, Alexander
Publicado 2021

Feedforward regulation of mRNA stability by prolonged extracellular signal-regulated kinase activity

por Nagashima, Takeshi, Inoue, Norihiko, Yumoto, Noriko, Saeki, Yuko, Magi, Shigeyuki, Volinsky, Natalia, Sorkin, Alexander, Kholodenko, Boris N, Okada-Hatakeyama, Mariko
Publicado 2015

Time-resolved proximity labeling of protein networks associated with ligand-activated EGFR

por Verdaguer, Mireia Perez, Zhang, Tian, Surve, Sachin, Paulo, Joao A., Wallace, Callen, Watkins, Simon C., Gygi, Steven P., Sorkin, Alexander
Publicado 2022

Heterogeneities in Axonal Structure and Transporter Distribution Lower Dopamine Reuptake Efficiency

por Kaya, Cihan, Cheng, Mary H., Block, Ethan R., Bartol, Tom M., Sejnowski, Terrence J., Sorkin, Alexander, Faeder, James R., Bahar, Ivet
Publicado 2018

Term Human Placental Trophoblasts Express SARS-CoV-2 Entry Factors ACE2, TMPRSS2, and Furin

por Ouyang, Yingshi, Bagalkot, Tarique, Fitzgerald, Wendy, Sadovsky, Elena, Chu, Tianjiao, Martínez-Marchal, Ana, Brieño-Enríquez, Miguel, Su, Emily J., Margolis, Leonid, Sorkin, Alexander, Sadovsky, Yoel
Publicado 2021