Behavioral and Biochemical Assessment of Monoaminergic Neural Transplants to Rat Frontal Neocortex

por Sortwell, Caryl E., Sagen, Jacqueline
Publicado 1992

BDNF provides many routes toward STN DBS‐mediated disease modification

por Fischer, D. Luke, Sortwell, Caryl E.
Publicado 2018

Synucleinopathy-associated pathogenesis in Parkinson’s disease and the potential for brain-derived neurotrophic factor

por Miller, Kathryn M., Mercado, Natosha M., Sortwell, Caryl E.
Publicado 2021

Cell therapy for Parkinson's disease: Why it doesn't work every time

por Collier, Timothy J., Sortwell, Caryl E., Mercado, Natosha M., Steece‐Collier, Kathy
Publicado 2019

Silencing Alpha Synuclein in Mature Nigral Neurons Results in Rapid Neuroinflammation and Subsequent Toxicity

por Benskey, Matthew J., Sellnow, Rhyomi C., Sandoval, Ivette M., Sortwell, Caryl E., Lipton, Jack W., Manfredsson, Fredric P.
Publicado 2018

Quality Over Quantity: Advantages of Using Alpha-Synuclein Preformed Fibril Triggered Synucleinopathy to Model Idiopathic Parkinson’s Disease

por Duffy, Megan F., Collier, Timothy J., Patterson, Joseph R., Kemp, Christopher J., Fischer, D. Luke, Stoll, Anna C., Sortwell, Caryl E.
Publicado 2018

ETMR-18. TARGETING Lin28 IN ETMR WITH ODC1 INHIBITOR DFMO

por Goodyke, Austin, Kelly, Shannon, Zagorski, Joseph, VanSickle, Elizabeth, Maser, Tyler, Sortwell, Caryl, Kemp, Christopher, Nagulapally, Abhinav, Dykema, Karl, Saulnier-Sholler, Giselle
Publicado 2020

Microglial depletion does not impact alpha-synuclein aggregation or nigrostriatal degeneration in the rat preformed fibril model

por Stoll, Anna C., Kemp, Christopher J., Patterson, Joseph R., Kubik, Michael, Kuhn, Nathan, Benskey, Matthew, Duffy, Megan F., Luk, Kelvin, Sortwell, Caryl E.
Publicado 2023

BDNF rs10501087, rs1491850 and rs11030094 polymorphisms associated with delayed progression in early-stage Parkinson's disease

por Fischer, D. Luke, Auinger, Peggy, Goudreau, John L., Paumier, Katrina L., Cole-Strauss, Allyson, Kemp, Christopher J., Lipton, Jack W., Sortwell, Caryl E.
Publicado 2022

Genetic silencing of striatal CaV1.3 prevents and ameliorates levodopa dyskinesia

por Steece‐Collier, Kathy, Stancati, Jennifer A., Collier, Nicholas J., Sandoval, Ivette M., Mercado, Natosha M., Sortwell, Caryl E., Collier, Timothy J., Manfredsson, Fredric P.
Publicado 2019

Downregulation of striatal Ca(V)1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

por Caulfield, Margaret E., Werp, Molly J. Vander, Stancati, Jennifer A., Collier, Timothy J., Sortwell, Caryl E., Sandoval, Ivette M., Manfredsson, Fredric P., Steece-Collier, Kathy
Publicado 2023

High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine

por Fischer, D. Luke, Collier, Timothy J., Cole-Strauss, Allyson, Wohlgenant, Susan L., Lipton, Jack W., Steece-Collier, Kathy, Manfredsson, Fredric P., Kemp, Christopher J., Sortwell, Caryl E.
Publicado 2015

Impact of age and vector construct on striatal and nigral transgene expression

por Polinski, Nicole K, Manfredsson, Fredric P, Benskey, Matthew J, Fischer, D Luke, Kemp, Christopher J, Steece-Collier, Kathy, Sandoval, Ivette M, Paumier, Katrina L, Sortwell, Caryl E
Publicado 2016

The Longitudinal Transcriptomic Response of the Substantia Nigra to Intrastriatal 6-Hydroxydopamine Reveals Significant Upregulation of Regeneration-Associated Genes

por Kanaan, Nicholas M., Collier, Timothy J., Cole-Strauss, Allyson, Grabinski, Tessa, Mattingly, Zachary R., Winn, Mary E., Steece-Collier, Kathy, Sortwell, Caryl E., Manfredsson, Fredric P., Lipton, Jack W.
Publicado 2015

Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS

por Kanaan, Nicholas M., Sellnow, Rhyomi C., Boye, Sanford L., Coberly, Ben, Bennett, Antonette, Agbandje-McKenna, Mavis, Sortwell, Caryl E., Hauswirth, William W., Boye, Shannon E., Manfredsson, Fredric P.
Publicado 2017

Dopaminergic Positron Emission Tomography Imaging in the Alpha‐Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease

por Sossi, Vesna, Patterson, Joseph R., McCormick, Siobhan, Kemp, Christopher J., Miller, Kathryn M., Stoll, Anna C., Kuhn, Nathan, Kubik, Michael, Kochmanski, Joseph, Luk, Kelvin C., Sortwell, Caryl E.
Publicado 2022

Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synuclein in the Rat Nigrostriatal System

por Gombash, Sara E., Manfredsson, Fredric P., Kemp, Christopher J., Kuhn, Nathan C., Fleming, Sheila M., Egan, Ann E., Grant, Laura M., Ciucci, Michelle R., MacKeigan, Jeffrey P., Sortwell, Caryl E.
Publicado 2013

Developmental exposure to the Parkinson’s disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mic...

por Boyd, Sierra L, Kuhn, Nathan C, Patterson, Joseph R, Stoll, Anna C, Zimmerman, Sydney A, Kolanowski, Mason R, Neubecker, Joseph J, Luk, Kelvin C, Ramsson, Eric S, Sortwell, Caryl E, Bernstein, Alison I
Publicado 2023

Striatal Afferent BDNF Is Disrupted by Synucleinopathy and Partially Restored by STN DBS

por Miller, Kathryn M., Patterson, Joseph R., Kochmanski, Joseph, Kemp, Christopher J., Stoll, Anna C., Onyekpe, Christopher U., Cole-Strauss, Allyson, Steece-Collier, Kathy, Howe, Jacob W., Luk, Kelvin C., Sortwell, Caryl E.
Publicado 2021

Best Practices for Generating and Using Alpha-Synuclein Pre-Formed Fibrils to Model Parkinson’s Disease in Rodents

por Polinski, Nicole K., Volpicelli-Daley, Laura A., Sortwell, Caryl E., Luk, Kelvin C., Cremades, Nunilo, Gottler, Lindsey M., Froula, Jessica, Duffy, Megan F., Lee, Virginia M.Y., Martinez, Terina N., Dave, Kuldip D.
Publicado 2018