Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo Lipogenesis

por Uehara, Kahealani, Sostre-Colón, Jaimarie, Gavin, Matthew, Santoleri, Dominic, Leonard, Kelly-Ann, Jacobs, René L., Titchenell, Paul M.
Publicado 2022

Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms

por Sostre-Colón, Jaimarie, Uehara, Kahealani, Garcia Whitlock, Anna E., Gavin, Matthew J., Ishibashi, Jeff, Potthoff, Matthew J., Seale, Patrick, Titchenell, Paul M.
Publicado 2021

Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes

por Angueira, Anthony R., Shapira, Suzanne N., Ishibashi, Jeff, Sampat, Samay, Sostre-Colón, Jaimarie, Emmett, Matthew J., Titchenell, Paul M., Lazar, Mitchell A., Lim, Hee-Woong, Seale, Patrick
Publicado 2020

AKT controls protein synthesis and oxidative metabolism via combined mTORC1 and FOXO1 signalling to govern muscle physiology

por Jaiswal, Natasha, Gavin, Matthew, Loro, Emanuele, Sostre‐Colón, Jaimarie, Roberson, Paul A., Uehara, Kahealani, Rivera‐Fuentes, Nicole, Neinast, Michael, Arany, Zoltan, Kimball, Scot R., Khurana, Tejvir S., Titchenell, Paul M.
Publicado 2021

Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity

por Santoleri, Dominic, Lim, Hee-Woong, Emmett, Matthew J., Stoute, Julian, Gavin, Matthew J., Sostre-Colón, Jaimarie, Uehara, Kahealani, Welles, Jaclyn E., Liu, Kathy Fange, Lazar, Mitchell A., Titchenell, Paul M.
Publicado 2022

Concomitant western diet and chronic-binge alcohol dysregulate hepatic metabolism

por Buyco, Delfin Gerard, Dempsey, Joseph L., Scorletti, Eleonora, Jeon, Sookyoung, Lin, Chelsea, Harkin, Julia, Bayen, Susovon, Furth, Emma E., Martin, Jasmin, Delima, Monique, Hooks, Royce, Sostre-Colón, Jaimarie, Gharib, Sina A., Titchenell, Paul M., Carr, Rotonya M.
Publicado 2023

YAP1 enhances NF-κB-dependent and independent effects on clock-mediated unfolded protein responses and autophagy in sarcoma

por Rivera-Reyes, Adrian, Ye, Shuai, E. Marino, Gloria, Egolf, Shaun, E. Ciotti, Gabrielle, Chor, Susan, Liu, Ying, Posimo, Jessica M., Park, Paul M. C., Pak, Koreana, Babichev, Yael, Sostre-Colón, Jaimarie, Tameire, Feven, Leli, Nektaria Maria, Koumenis, Constantinos, C. Brady, Donita, Mancuso, Anthony, Weber, Kristy, Gladdy, Rebecca, Qi, Jun, Eisinger-Mathason, T. S. Karin
Publicado 2018