Deficiency of Complement Component C1Q Prevents Cerebrovascular Damage and White Matter Loss in a Mouse Model of Chronic Obesity

por Graham, Leah C., Kocalis, Heidi E., Soto, Ileana, Howell, Gareth R.
Publicado 2020

Clustering of transcriptional profiles identifies changes to insulin signaling as an early event in a mouse model of Alzheimer’s disease

por Jackson, Harriet M, Soto, Ileana, Graham, Leah C, Carter, Gregory W, Howell, Gareth R
Publicado 2013

Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice

por Howell, Gareth R, Soto, Ileana, Ryan, Margaret, Graham, Leah C, Smith, Richard S, John, Simon WM
Publicado 2013

DBA/2J Mice Are Susceptible to Diabetic Nephropathy and Diabetic Exacerbation of IOP Elevation

por Soto, Ileana, Howell, Gareth R., John, Cai W., Kief, Joseph L., Libby, Richard T., John, Simon W. M.
Publicado 2014

Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease

por Graham, Leah C., Harder, Jeffrey M., Soto, Ileana, de Vries, Wilhelmine N., John, Simon W. M., Howell, Gareth R.
Publicado 2016

Selective pattern of motor system damage in gamma-synuclein transgenic mice mirrors the respective pathology in amyotrophic lateral sclerosis

por Peters, Owen M., Millership, Steven, Shelkovnikova, Tatyana A., Soto, Ileana, Keeling, Lora, Hann, Anthony, Marsh-Armstrong, Nicholas, Buchman, Vladimir L., Ninkina, Natalia
Publicado 2012

Jnk2 deficiency increases the rate of glaucomatous neurodegeneration in ocular hypertensive DBA/2J mice

por Harder, Jeffrey M., Williams, Pete A., Soto, Ileana, Foxworth, Nicole E., Fernandes, Kimberly A., Freeburg, Nelson F., Libby, Richard T., John, Simon. W. M.
Publicado 2018

APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction

por Soto, Ileana, Graham, Leah C., Richter, Hannah J., Simeone, Stephen N., Radell, Jake E., Grabowska, Weronika, Funkhouser, W. Keith, Howell, Megan C., Howell, Gareth R.
Publicado 2015

Trehalose enhances mitochondria deficits in human NPC1 mutant fibroblasts but disrupts mouse Purkinje cell dendritic growth ex vivo

por MacLeod, Collin M., Yousufzai, Fawad A. K., Spencer, Liam T., Kim, Sarah, Rivera-Rosario, Lucianne A., Barrera, Zerian D., Walsh, Lindsay, Krummenacher, Claude, Carone, Benjamin, Soto, Ileana
Publicado 2023

NPC1 deficiency impairs cerebellar postnatal development of microglia and climbing fiber refinement in a mouse model of Niemann–Pick disease type C

por Boyle, Bridget R., Melli, Sierra E., Altreche, Ruth S., Padron, Zachary M., Yousufzai, Fawad A. K., Kim, Sarah, Vasquez, Mariella D., Carone, Dawn M., Carone, Benjamin R., Soto, Ileana
Publicado 2020

Meox2 Haploinsufficiency Accelerates Axonal Degeneration in DBA/2J Glaucoma

por Buchanan, Rebecca A., Foley, Kate E., Pepper, Keating W., Reagan, Alaina M., Keezer, Kelly J., Hewes, Amanda A., Diemler, Cory A., Preuss, Christoph, Soto, Ileana, John, Simon W. M., Howell, Gareth R.
Publicado 2019

Increased interactions and engulfment of dendrites by microglia precede Purkinje cell degeneration in a mouse model of Niemann Pick Type-C

por Kavetsky, Larisa, Green, Kayla K., Boyle, Bridget R., Yousufzai, Fawad A. K., Padron, Zachary M., Melli, Sierra E., Kuhnel, Victoria L., Jackson, Harriet M., Blanco, Rosa E., Howell, Gareth R., Soto, Ileana
Publicado 2019

Enhancing face validity of mouse models of Alzheimer’s disease with natural genetic variation

por Onos, Kristen D., Uyar, Asli, Keezer, Kelly J., Jackson, Harriet M., Preuss, Christoph, Acklin, Casey J., O’Rourke, Rita, Buchanan, Rebecca, Cossette, Travis L., Sukoff Rizzo, Stacey J., Soto, Ileana, Carter, Gregory W., Howell, Gareth R.
Publicado 2019

Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease

por Kim, Sarah, Ochoa, Kathleen, Melli, Sierra E., Yousufzai, Fawad A. K., Barrera, Zerian D., Williams, Aela A., McIntyre, Gianna, Delgado, Esteban, Bolish, James N., Macleod, Collin M., Boghos, Mary, Lens, Hayden P., Ramos, Alex G., Wilson, Vincent B., Maloney, Kelly, Padron, Zachary M., Khan, Amaal H., Blanco, Rosa E., Soto, Ileana
Publicado 2023

ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma

por Nongpiur, Monisha E., Khor, Chiea Chuen, Jia, Hongyan, Cornes, Belinda K., Chen, Li-Jia, Qiao, Chunyan, Nair, K. Saidas, Cheng, Ching-Yu, Xu, Liang, George, Ronnie, Tan, Do, Abu-Amero, Khaled, Perera, Shamira A., Ozaki, Mineo, Mizoguchi, Takanori, Kurimoto, Yasuo, Low, Sancy, Tajudin, Liza-Sharmini A., Ho, Ching-Lin, Tham, Clement C. Y., Soto, Ileana, Chew, Paul T. K., Wong, Hon-Tym, Shantha, Balekudaru, Kuroda, Masako, Osman, Essam A., Tang, Guangxian, Fan, Sujie, Meng, Hailin, Wang, Hua, Feng, Bo, Yong, Victor H. K., Ting, Serena M. L., Li, Yang, Wang, Ya-Xing, Li, Zheng, Lavanya, Raghavan, Wu, Ren-Yi, Zheng, Ying-Feng, Su, Daniel H., Loon, Seng-Chee, Allingham, R. Rand, Hauser, Michael A., Soumittra, Nagaswamy, Ramprasad, Vedam L., Waseem, Naushin, Yaakub, Azhany, Chia, Kee-Seng, Kumaramanickavel, Govindasamy, Wong, Tina T., How, Alicia C., Chau, Tran Nguyen Bich, Simmons, Cameron P., Bei, Jin-Xin, Zeng, Yi-Xin, Bhattacharya, Shomi S., Zhang, Mingzhi, Tan, Donald T., Teo, Yik-Ying, Al-Obeidan, Saleh A., Hon, Do Nhu, Tai, E-Shyong, Saw, Seang-Mei, Foster, Paul J., Vijaya, Lingam, Jonas, Jost B., Wong, Tien-Yin, John, Simon W. M., Pang, Chi-Pui, Vithana, Eranga N., Wang, Ningli, Aung, Tin
Publicado 2014