Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer's Disease Mutations

por Soto-Ospina, Alejandro, Araque Marín, Pedronel, Bedoya, Gabriel de Jesús, Villegas Lanau, Andrés
Publicado 2021

Protein Predictive Modeling and Simulation of Mutations of Presenilin-1 Familial Alzheimer’s Disease on the Orthosteric Site

por Soto-Ospina, Alejandro, Araque Marín, Pedronel, Bedoya, Gabriel, Sepulveda-Falla, Diego, Villegas Lanau, Andrés
Publicado 2021

Diffusion Mechanism Modeling of Metformin in Human Organic Cationic Amino Acid Transporter one and Functional Impact of S189L, R206C, and G401S Mutation

por Cano, Leydy, Soto-Ospina, Alejandro, Araque, Pedronel, Caro-Gomez, Maria Antonieta, Parra-Marin, Maria Victoria, Bedoya, Gabriel, Duque, Constanza
Publicado 2021

Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1(I249/M280) Variant

por Cardona, Sandra M., Kim, Sangwon V., Church, Kaira A., Torres, Vanessa O., Cleary, Ian A., Mendiola, Andrew S., Saville, Stephen P., Watowich, Stephanie S., Parker-Thornburg, Jan, Soto-Ospina, Alejandro, Araque, Pedronel, Ransohoff, Richard M., Cardona, Astrid E.
Publicado 2018

Mutations in SORL1 and MTHFDL1 possibly contribute to the development of Alzheimer’s disease in a multigenerational Colombian Family

por Tejada Moreno, Johanna Alexandra, Villegas Lanau, Andrés, Madrigal Zapata, Lucia, Baena Pineda, Ana Yulied, Velez Hernandez, Juan, Campo Nieto, Omer, Soto Ospina, Alejandro, Araque Marín, Pedronel, Rishishwar, Lavanya, Norris, Emily T., Chande, Aroon T., Jordan, I. King, Bedoya Berrio, Gabriel
Publicado 2022

Structural Protein Effects Underpinning Cognitive Developmental Delay of the PURA p.Phe233del Mutation Modelled by Artificial Intelligence and the Hybrid Quantum Mechanics–Molecula...

por López-Rivera, Juan Javier, Rodríguez-Salazar, Luna, Soto-Ospina, Alejandro, Estrada-Serrato, Carlos, Serrano, David, Chaparro-Solano, Henry Mauricio, Londoño, Olga, Rueda, Paula A., Ardila, Geraldine, Villegas-Lanau, Andrés, Godoy-Corredor, Marcela, Cuartas, Mauricio, Vélez, Jorge I., Vidal, Oscar M., Isaza-Ruget, Mario A., Arcos-Burgos, Mauricio
Publicado 2022