Mitochondrial apoptotic priming is a key determinant of cell fate upon p53 restoration

por Sánchez-Rivera, Francisco J., Ryan, Jeremy, Soto-Feliciano, Yadira M., Clare Beytagh, Mary, Xuan, Lucius, Feldser, David M., Hemann, Michael T., Zamudio, Jesse, Dimitrova, Nadya, Letai, Anthony, Jacks, Tyler
Publicado 2021

A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth

por Meacham, Corbin E., Lawton, Lee N., Soto-Feliciano, Yadira M., Pritchard, Justin R., Joughin, Brian A., Ehrenberger, Tobias, Fenouille, Nina, Zuber, Johannes, Williams, Richard T., Young, Richard A., Hemann, Michael T.
Publicado 2015

PHF6 regulates phenotypic plasticity through chromatin organization within lineage-specific genes

por Soto-Feliciano, Yadira M., Bartlebaugh, Jordan M.E., Liu, Yunpeng, Sánchez-Rivera, Francisco J., Bhutkar, Arjun, Weintraub, Abraham S., Buenrostro, Jason D., Cheng, Christine S., Regev, Aviv, Jacks, Tyler E., Young, Richard A., Hemann, Michael T.
Publicado 2017

Context-defined cancer co-dependency mapping identifies a functional interplay between PRC2 and MLL-MEN1 complex in lymphoma

por Chen, Xiao, Li, Yinglu, Zhu, Fang, Xu, Xinjing, Estrella, Brian, Pazos, Manuel A., McGuire, John T., Karagiannis, Dimitris, Sahu, Varun, Mustafokulov, Mustafo, Scuoppo, Claudio, Sánchez-Rivera, Francisco J., Soto-Feliciano, Yadira M., Pasqualucci, Laura, Ciccia, Alberto, Amengual, Jennifer E., Lu, Chao
Publicado 2023

MLL3 regulates the CDKN2A tumor suppressor locus in liver cancer

por Zhu, Changyu, Soto-Feliciano, Yadira M, Morris, John P, Huang, Chun-Hao, Koche, Richard P, Ho, Yu-jui, Banito, Ana, Chen, Chun-Wei, Shroff, Aditya, Tian, Sha, Livshits, Geulah, Chen, Chi-Chao, Fennell, Myles, Armstrong, Scott A, Allis, C David, Tschaharganeh, Darjus F, Lowe, Scott W
Publicado 2023

Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors

por Hoffmann, H.-Heinrich, Sánchez-Rivera, Francisco J., Schneider, William M., Luna, Joseph M., Soto-Feliciano, Yadira M., Ashbrook, Alison W., Le Pen, Jérémie, Leal, Andrew A., Ricardo-Lax, Inna, Michailidis, Eleftherios, Hao, Yuan, Stenzel, Ansgar F., Peace, Avery, Zuber, Johannes, Allis, C. David, Lowe, Scott W., MacDonald, Margaret R., Poirier, John T., Rice, Charles M.
Publicado 2021

High-resolution characterization of gene function using single-cell CRISPR tiling screen

por Yang, Lu, Chan, Anthony K. N., Miyashita, Kazuya, Delaney, Christopher D., Wang, Xi, Li, Hongzhi, Pokharel, Sheela Pangeni, Li, Sandra, Li, Mingli, Xu, Xiaobao, Lu, Wei, Liu, Qiao, Mattson, Nicole, Chen, Kevin Yining, Wang, Jinhui, Yuan, Yate-Ching, Horne, David, Rosen, Steven T., Soto-Feliciano, Yadira, Feng, Zhaohui, Hoshii, Takayuki, Xiao, Gang, Müschen, Markus, Chen, Jianjun, Armstrong, Scott A., Chen, Chun-Wei
Publicado 2021

A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin–MLL Inhibition

por Soto-Feliciano, Yadira M., Sánchez-Rivera, Francisco J., Perner, Florian, Barrows, Douglas W., Kastenhuber, Edward R., Ho, Yu-Jui, Carroll, Thomas, Xiong, Yijun, Anand, Disha, Soshnev, Alexey A., Gates, Leah, Beytagh, Mary Clare, Cheon, David, Gu, Shengqing, Liu, X. Shirley, Krivtsov, Andrei V., Meneses, Maximiliano, de Stanchina, Elisa, Stone, Richard M., Armstrong, Scott A., Lowe, Scott W., Allis, C. David
Publicado 2023