Oleate induces K(ATP) channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge

por Dadak, Selma, Beall, Craig, Vlachaki Walker, Julia M., Soutar, Marc P.M., McCrimmon, Rory J., Ashford, Michael L.J.
Publicado 2017

Inhibition of LRRK2 kinase activity stimulates macroautophagy()

por Manzoni, Claudia, Mamais, Adamantios, Dihanich, Sybille, Abeti, Rosella, Soutar, Marc P.M., Plun-Favreau, Helene, Giunti, Paola, Tooze, Sharon A., Bandopadhyay, Rina, Lewis, Patrick A.
Publicado 2013

mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1

por Manzoni, Claudia, Mamais, Adamantios, Roosen, Dorien A., Dihanich, Sybille, Soutar, Marc P. M., Plun-Favreau, Helene, Bandopadhyay, Rina, Hardy, John, Tooze, Sharon A., Cookson, Mark R., Lewis, Patrick A.
Publicado 2016

mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition

por Manzoni, Claudia, Mamais, Adamantios, Dihanich, Sybille, Soutar, Marc P.M., Plun-Favreau, Helene, Bandopadhyay, Rina, Abeti, Rosella, Giunti, Paola, Hardy, John, R. Cookson, Mark, Tooze, Sharon A., Lewis, Patrick A.
Publicado 2018

AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons

por Soutar, Marc P. M., Kempthorne, Liam, Miyakawa, Shuichi, Annuario, Emily, Melandri, Daniela, Harley, Jasmine, O’Sullivan, Gregory A., Wray, Selina, Hancock, David C., Cookson, Mark R., Downward, Julian, Carlton, Mark, Plun-Favreau, Hélène
Publicado 2018

Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci

por Soutar, Marc P M, Melandri, Daniela, O’Callaghan, Benjamin, Annuario, Emily, Monaghan, Amy E, Welsh, Natalie J, D’Sa, Karishma, Guelfi, Sebastian, Zhang, David, Pittman, Alan, Trabzuni, Daniah, Verboven, Anouk H A, Pan, Kylie S, Kia, Demis A, Bictash, Magda, Gandhi, Sonia, Houlden, Henry, Cookson, Mark R, Kasri, Nael Nadif, Wood, Nicholas W, Singleton, Andrew B, Hardy, John, Whiting, Paul J, Blauwendraat, Cornelis, Whitworth, Alexander J, Manzoni, Claudia, Ryten, Mina, Lewis, Patrick A, Plun-Favreau, Hélène
Publicado 2022

Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification

por Schottlaender, Lucia V., Abeti, Rosella, Jaunmuktane, Zane, Macmillan, Carol, Chelban, Viorica, O’Callaghan, Benjamin, McKinley, John, Maroofian, Reza, Efthymiou, Stephanie, Athanasiou-Fragkouli, Alkyoni, Forbes, Raeburn, Soutar, Marc P.M., Livingston, John H., Kalmar, Bernardett, Swayne, Orlando, Hotton, Gary, Pittman, Alan, Mendes de Oliveira, João Ricardo, de Grandis, Maria, Richard-Loendt, Angela, Launchbury, Francesca, Althonayan, Juri, McDonnell, Gavin, Carr, Aisling, Khan, Suliman, Beetz, Christian, Bisgin, Atil, Tug Bozdogan, Sevcan, Begtrup, Amber, Torti, Erin, Greensmith, Linda, Giunti, Paola, Morrison, Patrick J., Brandner, Sebastian, Aurrand-Lions, Michel, Houlden, Henry
Publicado 2020