Monitoring cancer prognosis, diagnosis and treatment efficacy using metabolomics and lipidomics

por Armitage, Emily G., Southam, Andrew D.
Publicado 2016

Characterisation of the dynamic nature of lipids throughout the lifespan of genetically identical female and male Daphnia magna

por Constantinou, Julia K., Southam, Andrew D., Kvist, Jouni, Jones, Martin R., Viant, Mark R., Mirbahai, Leda
Publicado 2020

Distinguishing between the metabolome and xenobiotic exposome in environmental field samples analysed by direct-infusion mass spectrometry based metabolomics and lipidomics

por Southam, Andrew D., Lange, Anke, Al-Salhi, Raghad, Hill, Elizabeth M., Tyler, Charles R., Viant, Mark R.
Publicado 2014

Cytoglobin protects cancer cells from apoptosis by regulation of mitochondrial cardiolipin

por Thorne, Lorna S., Rochford, Garret, Williams, Timothy D., Southam, Andrew D., Rodriguez-Blanco, Giovanny, Dunn, Warwick B., Hodges, Nikolas J.
Publicado 2021

Metabolomics Reveals Target and Off-Target Toxicities of a Model Organophosphate Pesticide to Roach (Rutilus rutilus): Implications for Biomonitoring

por Southam, Andrew D., Lange, Anke, Hines, Adam, Hill, Elizabeth M., Katsu, Yoshinao, Iguchi, Taisen, Tyler, Charles R., Viant, Mark R.
Publicado 2011

Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium

por Wang-Kan, Xuan, Rodríguez-Blanco, Giovanny, Southam, Andrew D., Winder, Catherine L., Dunn, Warwick B., Ivens, Alasdair, Piddock, Laura J. V.
Publicado 2021

Simultaneously discovering the fate and biochemical effects of pharmaceuticals through untargeted metabolomics

por Bowen, Tara J., Southam, Andrew D., Hall, Andrew R., Weber, Ralf J. M., Lloyd, Gavin R., Macdonald, Ruth, Wilson, Amanda, Pointon, Amy, Viant, Mark R.
Publicado 2023

Combined bezafibrate, medroxyprogesterone acetate and valproic acid treatment inhibits osteosarcoma cell growth without adversely affecting normal mesenchymal stem cells

por Sheard, Jonathan J., Southam, Andrew D., MacKay, Hannah L., Ellington, Max A., Snow, Martyn D., Khanim, Farhat L., Bunce, Christopher M., Johnson, William E.
Publicado 2021

Disruption of DNA methylation via S-adenosylhomocysteine is a key process in high incidence liver carcinogenesis

por Mirbahai, Leda, Williams, Tim D, Yin, Guangliang, Southam, Andrew D, Sommer, Ulf, Li, Ning, Bignell, John P, Lyons, Brett P, Viant, Mark R, Chipman, James K
Publicado 2013

Valproic acid disables the Nrf2 anti-oxidant response in acute myeloid leukaemia cells enhancing reactive oxygen species-mediated killing

por Jiang, Yao, Southam, Andrew D., Trova, Sandro, Beke, Flavio, Alhazmi, Bader, Francis, Thomas, Radotra, Anshul, di Maio, Alessandro, Drayson, Mark T., Bunce, Chris M., Khanim, Farhat L.
Publicado 2021

Suitability of Dried Blood Spots for Accelerating Veterinary Biobank Collections and Identifying Metabolomics Biomarkers With Minimal Resources

por Allaway, David, Alexander, Janet E., Carvell-Miller, Laura J., Reynolds, Rhiannon M., Winder, Catherine L., Weber, Ralf J. M., Lloyd, Gavin R., Southam, Andrew D., Dunn, Warwick B.
Publicado 2022

Metabolic characterisation of disturbances in the APOC3/triglyceride-rich lipoprotein pathway through sample-based recall by genotype

por Corbin, Laura J., Hughes, David A., Chetwynd, Andrew J., Taylor, Amy E., Southam, Andrew D., Jankevics, Andris, Weber, Ralf J. M., Groom, Alix, Dunn, Warwick B., Timpson, Nicholas J.
Publicado 2020

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma

por Bryant, Jennifer, Batis, Nikolaos, Franke, Anna Clara, Clancey, Gabriella, Hartley, Margaret, Ryan, Gordon, Brooks, Jill, Southam, Andrew D., Barnes, Nicholas, Parish, Joanna, Roberts, Sally, Khanim, Farhat, Spruce, Rachel, Mehanna, Hisham
Publicado 2019

Intermittent Surface Oxygenation Results in Similar Mitochondrial Protection and Maintenance of Aerobic Metabolism as Compared to Continuous Oxygenation during Hypothermic Machine...

por Darius, Tom, Vergauwen, Martial, Maistriaux, Louis, Evrard, Robin, Schlegel, Andrea, Mueller, Matteo, O’Neil, Donna, Southam, Andrew, Aydin, Selda, Devresse, Arnaud, De Meyer, Martine, Gianello, Pierre, Ludwig, Christian, Dutkowski, Philipp, Mourad, Michel
Publicado 2023

Cryptococcal 3-Hydroxy Fatty Acids Protect Cells Against Amoebal Phagocytosis

por Madu, Uju L., Ogundeji, Adepemi O., Mochochoko, Bonang M., Pohl, Carolina H., Albertyn, Jacobus, Swart, Chantel W., Allwood, J. William, Southam, Andrew D., Dunn, Warwick B., May, Robin C., Sebolai, Olihile M.
Publicado 2015

Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques

por Denbigh, Joanna L., Perez-Guaita, David, Vernooij, Robbin R., Tobin, Mark J., Bambery, Keith R., Xu, Yun, Southam, Andrew D., Khanim, Farhat L., Drayson, Mark T., Lockyer, Nicholas P., Goodacre, Royston, Wood, Bayden R.
Publicado 2017

Determining the role of novel metabolic pathways in driving intracranial pressure reduction after weight loss

por Alimajstorovic, Zerin, Mitchell, James L, Yiangou, Andreas, Hancox, Thomas, Southam, Andrew D, Grech, Olivia, Ottridge, Ryan, Winder, Catherine L, Tahrani, Abd A, Tan, Tricia M, Mollan, Susan P, Dunn, Warwick B, Sinclair, Alexandra J
Publicado 2023

Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment

por Stavrou, Victoria, Fultang, Livingstone, Booth, Sarah, De Simone, Daniele, Bartnik, Arekdiusz, Scarpa, Ugo, Gneo, Luciana, Panetti, Silvia, Potluri, Sandeep, Almowaled, Meaad, Barlow, Jonathan, Jankevics, Andris, Lloyd, Gavin, Southam, Andrew, Priestman, David A., Cheng, Paul, Dunn, Warwick, Platt, Frances, Endou, Hitoshi, Craddock, Charles, Keeshan, Karen, Mussai, Francis, De Santo, Carmela
Publicado 2022

Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached

por Wilcock, Daniel J., Badrock, Andrew P., Wong, Chun W., Owen, Rhys, Guerin, Melissa, Southam, Andrew D., Johnston, Hannah, Telfer, Brian A., Fullwood, Paul, Watson, Joanne, Ferguson, Harriet, Ferguson, Jennifer, Lloyd, Gavin R., Jankevics, Andris, Dunn, Warwick B., Wellbrock, Claudia, Lorigan, Paul, Ceol, Craig, Francavilla, Chiara, Smith, Michael P., Hurlstone, Adam F.L.
Publicado 2022